The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Hightlights and Diagnostic Dilemma of Toxocariasis

개회충증의 핵심과 진단의 딜레마

  • Lee, Sang Pyo (Department of Internal Medicine, Gil Medical Center, Gachon Medical School)
  • 이상표 (가천의과학대학교 길병원 내과)
  • Published : 2013.02.01
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Abstract

Toxocariasis is an endemic parasitic infection and one of the most common causes of peripheral blood eosinophilia in Korea. The clinical manifestation is atypical, which makes it difficult to distinguish toxocariasis from other clinical conditions. Serologic tests for helminthic or protozoal infections frequently show positive results in general population and measurement of serum specific immunoglobulin G (IgG) antibody against Toxocaria canis (T. canis) using Enzyme-linked immunosorbent assay (ELISA) has a problem of cross-reactivity with those helminthes or protozoas in Korea. To avoid problems of cross-reactivity with other helminthes or protozoas and ensure the diagnosis of toxocariasis, western blotting procedure with excretory-secretory antigens from T. canis larvae was recommended.

Keywords

References

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