The Korean Journal of Medicine

  • 제84권5호
  • /
  • Pages.704-707
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  • 2013
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  • 1738-9364(pISSN)
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  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
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대장 용종에 국한되어 발생한 랑게르한스 세포 조직구증 1예

Colonic Langerhans Cell Histiocytosis Presenting as an Isolated Polyp

  • 서현웅 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 한군희 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 김성훈 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 홍만용 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 윤정호 (울산대학교 의과대학 강릉아산병원 내과) ;
  • 엄대운 (울산대학교 의과대학 강릉아산병원 병리과) ;
  • 천갑진 (울산대학교 의과대학 강릉아산병원 내과)
  • Seo, Hyun Woong (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Han, Koon Hee (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Kim, Sunghun (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Hong, Man Yong (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Yun, Jung Ho (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Eom, Dae Woon (Department of Pathology, Gangneung Asan Hospital, University of Ulsan College of Medicine) ;
  • Cheon, Gab Jin (Department of Internal Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine)
  • 투고 : 2012.07.31
  • 심사 : 2012.10.02
  • 발행 : 2013.05.01
⟨ 이전 논문 다음 논문 ⟩

초록

저자들은 무증상의 환자에서 시행한 검진 대장내시경에서 무경성 용종을 용종 절제술을 통해 제거하고 이에 대한 조직 검사에서 랑게르한스 세포 조직구의 침윤이 관찰되고 면역 화학 염색에서 S-100 protein과 CD1a 항원 양성 소견을 보여 랑게르한스 세포 조직구증을 진단하였으며 타장기 침범 소견이 없어 경과관찰 중인 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

A 56-year-old male underwent a screening colonoscopy. An 8-mm sessile polyp was removed from the descending colon using snare polypectomy. Histology showed Langerhans cells and eosinophil infiltration of the submucosa. Immunohistochemical staining was positive for S-100 protein and CD1a antigen, which confirmed the diagnosis of Langerhans-cell histiocytosis. On further workup, there was no evidence of involvement of any other organs. Here, we report a very rare case of colonic Langerhans-cell histiocytosis presenting as an isolated polyp.

키워드

참고문헌

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