The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Complete Heart Block in a Patient with Myasthenia Gravis Associated with Thymoma

흉선종이 동반된 중증 근육무력증 환자에서 발생한 완전 방실 전도 차단

  • Kim, Song I (Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Kim, Nam-Ho (Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Jo, Hoon Gil (Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Kim, Eun Kyoung (Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Ko, Jum Suk (Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Rhee, Sang Jae (Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine) ;
  • Yun, Kyeong Ho (Department of Internal Medicine, Wonkwang University Hospital, Wonkwang University School of Medicine)
  • 김송이 (원광대학교 의과대학 원광대학교병원 내과) ;
  • 김남호 (원광대학교 의과대학 원광대학교병원 내과) ;
  • 조훈길 (원광대학교 의과대학 원광대학교병원 내과) ;
  • 김은경 (원광대학교 의과대학 원광대학교병원 내과) ;
  • 고점석 (원광대학교 의과대학 원광대학교병원 내과) ;
  • 이상재 (원광대학교 의과대학 원광대학교병원 내과) ;
  • 윤경호 (원광대학교 의과대학 원광대학교병원 내과)
  • Received : 2012.11.27
  • Accepted : 2013.02.12
  • Published : 2013.12.01
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Abstract

Myasthenia gravis is an autoimmune disorder characterized by antibodies against acetylcholine receptors in skeletal muscle. Myocardial involvement can present as myocarditis, ventricular tachycardia, heart failure and sudden death. However, advanced heart block is a very rare symptom. We report the case of a 69-year-old male who experienced dizziness and ptosis for one-month prior. He was diagnosed with myasthenia gravis and thymoma accompanied by complete atrioventricular block. The dizziness disappeared after implantation of a permanent pacemaker and the advanced heart block was resolved after surgical removal of the thymoma.

중증 근육무력증은 그 기전은 명확하지 않으나 드물게는 심장을 침범하여 심근염, 심부전증, 부정맥 등 다양한 임상양상을 나타낼 수 있다. 이 중 전도장애도 나타날 수 있는데, 완전 방실전도차단은 매우 드문 현상이다. 저자들은 안검하수 및 어지러움을 주소로 내원한 69세 남자 환자에서 흉선종을 동반한 중증 근육무력증과 완전 방실전도차단을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

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  1. Cardiomyopathy in Patients with Myasthenia Gravis Crisis vol.37, pp.4, 2019, https://doi.org/10.17340/jkna.2019.4.13