The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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Pathophysiology of Colon Diverticulum

대장게실의 병태 생리

  • Kim, Seong-Eun (Department of Internal Medicine, Ewha Womans University School of Medicine)
  • 김성은 (이화여자대학교 의학전문대학원 내과학교실)
  • Published : 2013.12.01
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Abstract

Although the pathogenesis of diverticulum remains unclear, traditionally it has been thought to result from structural abnormalities of the colonic wall, deficiencies of dietary fiber, or disordered intestinal motility. More recently, new pathophysiologic factors including inflammation, gut flora, neurotransmitters, visceral hypersensitivity, and chemical mediators are proposed, and their mechanism of interactions in developing diverticulum is quite complex and currently poorly understood. Future studies are needed to find out the multifaceted pathogenesis of diverticulum, ultimately for the treatment and prevention of disease.

Keywords

References

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