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비장의 단독전이로 재발한 두경부암

Solitary Splenic Metastasis from Head and Neck Cancer: A Case Report

  • 서경진 (서울대학교병원 내과) ;
  • 김범석 (서울대학교병원 내과) ;
  • 임진 (서울대학교병원 내과) ;
  • 김미소 (서울대학교병원 내과) ;
  • 이대원 (서울대학교병원 내과) ;
  • 김동영 (서울대학교병원 이비인후과) ;
  • 우홍균 (서울대학교병원 방사선종양학과)
  • Suh, Koung Jin (Department of Internal Medicine, Seoul National University Hospital, Seoul National University Collge of Medicine) ;
  • Keam, Bhumsuk (Department of Internal Medicine, Seoul National University Hospital, Seoul National University Collge of Medicine) ;
  • Im, Jin (Department of Internal Medicine, Seoul National University Hospital, Seoul National University Collge of Medicine) ;
  • Kim, Mi So (Department of Internal Medicine, Seoul National University Hospital, Seoul National University Collge of Medicine) ;
  • Lee, Dae-Won (Department of Internal Medicine, Seoul National University Hospital, Seoul National University Collge of Medicine) ;
  • Kim, Dong-Young (Department of Otorhinolaryngology, Seoul National University Hospital, Seoul National University Collge of Medicine) ;
  • Wu, Hong-Gyun (Department of Radiation Oncology, Seoul National University Hospital, Seoul National University Collge of Medicine)
  • 투고 : 2013.02.16
  • 심사 : 2013.04.04
  • 발행 : 2013.09.01

초록

Solitary splenic metastases from head and neck cancer are rare. We report a 35-year-old male with nasal cavity cancer with metastasis to the cervical lymph nodes. The patient underwent three cycles of induction chemotherapy, followed by left medial maxillectomy with modified radical neck dissection and concurrent chemoradiotherapy with weekly cisplatin. After 7 months of a disease-free interval, positron-emission tomography showed a high uptake in the spleen, and a biopsy confirmed metastatic carcinoma. After four cycles of systemic chemotherapy with docetaxel and cisplatin, laparoscopic splenectomy was performed. This case highlights that solitary splenic metastasis, although rare, may occur with a locoregionally controlled head and neck cancer and could be treated with local and systemic treatment.

키워드

참고문헌

  1. Lam KY, Tang V. Metastatic tumors to the spleen: a 25-year clinicopathologic study. Arch Pathol Lab Med 2000;124: 526-530.
  2. Comperat E, Bardier-Dupas A, Camparo P, Capron F, Charlotte F. Splenic metastases: clinicopathologic presentation, differential diagnosis, and pathogenesis. Arch Pathol Lab Med 2007;131:965-969.
  3. Vyas SJ, Chitale AR, Deshpande RK. Late splenic metastasis after curative resection for oesophageal carcinoma. Eur J Cardiothorac Surg 2002;22:1011-1013. https://doi.org/10.1016/S1010-7940(02)00580-8
  4. Ferlito A, Shaha AR, Silver CE, Rinaldo A, Mondin V. Incidence and sites of distant metastases from head and neck cancer. ORL J Otorhinolaryngol Relat Spec 2001;63:202-207. https://doi.org/10.1159/000055740
  5. Kotwall C, Sako K, Razack MS, Rao U, Bakamjian V, Shedd DP. Metastatic patterns in squamous cell cancer of the head and neck. Am J Surg 1987;154:439-442. https://doi.org/10.1016/0002-9610(89)90020-2
  6. Raval MV, Zemon H, Kumar SS, Brody FJ. Laparoscopic splenectomy for metastatic squamous cell cancer of the neck. J Laparoendosc Adv Surg Tech A 2005;15:383-386. https://doi.org/10.1089/lap.2005.15.383
  7. Cohen EE, Lingen MW, Vokes EE. The expanding role of systemic therapy in head and neck cancer. J Clin Oncol 2004;22:1743-1752. https://doi.org/10.1200/JCO.2004.06.147
  8. Wong LY, Wei WI, Lam LK, Yuen AP. Salvage of recurrent head and neck squamous cell carcinoma after primary curative surgery. Head Neck 2003;25:953-959. https://doi.org/10.1002/hed.10310
  9. Yamanouchi K, Ikematsu Y, Waki S, et al. Solitary splenic metastasis from gastric cancer: report of a case. Surg Today 2002;32:1081-1084. https://doi.org/10.1007/s005950200218
  10. Okuyama T, Oya M, Ishikawa H. Isolated splenic metastasis of sigmoid colon cancer: a case report. Jpn J Clin Oncol 2001;31:341-345. https://doi.org/10.1093/jjco/hye065

피인용 문헌

  1. Solitary splenic metastasis from nasopharyngeal carcinoma: a case report and systematic review of the literature vol.14, pp.None, 2013, https://doi.org/10.1186/s12957-016-0941-2