Journal of Environmental Science International (한국환경과학회지)

The Korean Environmental Sciences Society (한국환경과학회)
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Effects of Cordyceps Militaris on the Improvement Actions of Blood Glucose and Atherosclerosis in Diabetes

동충하초(Cordyceps militaris)가 당뇨의 혈당 및 동맥경화 개선에 미치는 영향

  • Kim, Han-Soo (Department of Food Science & Technology, Pusan National University) ;
  • Kim, Min-A (Department of Food Science & Technology, Pusan National University) ;
  • Jang, Seong-Ho (Department of Bioenviromental Energy, Pusan National University) ;
  • Kang, Dong-Soo (Division of Food Technology & Nutrition, Chonnam National University) ;
  • Lee, Won-Ki (Department of Polymer Engineering, Pukyung National University) ;
  • Ryu, Jae-Young (Division for Industrial & Environmental Research, Korea Atomic Energy Research Institute (KAERI)) ;
  • Lee, Chun-Sik (Department of Env. Eng., Gyeongnam National University of science and Technology)
  • 김한수 (부산대학교 식품공학과) ;
  • 김민아 (부산대학교 식품공학과) ;
  • 장성호 (부산대학교 바이오환경에너지학과) ;
  • 강동수 (전남대학교 식품공학.영양학부) ;
  • 이원기 (부경대학교 고분자공학과) ;
  • 류재용 (한국원자력연구원 공업환경연구부) ;
  • 이춘식 (경남과학기술대학교 환경공학과)
  • Received : 2012.12.13
  • Accepted : 2013.03.19
  • Published : 2013.03.29
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Abstract

The purpose of this study was to assess the effects of Cordyceps militaris extract supplementation on the improvement of blood glucose, lipid compositions and hepatic functional enzyme activities in the serum of streptozotocin(STZ, 50 mg/kg BW, IP injection)-induced diabetic rats fed the experimental diets for 5 weeks. The concentrations of blood glucose and lipid compositions(total cholesterol, ${\beta}$-lipoprotein, free cholesterol, cholesteryl ester, triglyceride and phospholipid) and atherosclerotic index in serum were significantly lower in the DM+CM group than in the DM group, whereas the ratio of HDL-cholesterol concentration to total cholesterol in the DM+CM group were higher than in the DM group. The activities of hepatic functional enzymes(aminotransferase, LDH and ALP) in serum were lower in the Cordyceps militaris extract administration group(group DM+CM) than in the hyperglycemic DM group. The results shown above suggested that Cordyceps militaris extract supplementation effectively improves blood glucose and atherosclerosis in the serum of diabetic rats.

Keywords

References

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