참고문헌
- Ornoy, A. (2006) Neuroteratogens in man: an overview with special emphasis on the teratogenicity of antiepileptic drugs in pregnancy. Reprod. Toxicol., 22, 214-226. https://doi.org/10.1016/j.reprotox.2006.03.014
- Rosenberg, G. (2007) The mechanisms of action of valproate in neuropsychiatric disorders: can we see the forest for the trees? Cell. Mol. Life Sci., 64, 2090-2103. https://doi.org/10.1007/s00018-007-7079-x
- Wide, K., Winbladh, B. and Källén, B. (2004) Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. Acta Paediatr., 93, 174-176. https://doi.org/10.1111/j.1651-2227.2004.tb00701.x
- Alsdorf, R. and Wyszynski, D.F. (2005) Teratogenicity of sodium valproate. Expert Opin. Drug Saf., 4, 345-353. https://doi.org/10.1517/14740338.4.2.345
- Binkerd, P.E., Rowland, J.M., Nau, H. and Hendrickx, A.G. (1988) Evaluation of valproic acid (VPA) developmental toxicity and pharmacokinetics in Sprague-Dawley rats. Fundam. Appl. Toxicol., 11, 485-493. https://doi.org/10.1016/0272-0590(88)90112-1
- Hawkes, W.C., Willhite, C.C., Omaye, S.T., Cox, D.N., Choy, W.N. and Tarantal, A.F. (1994) Selenium kinetics, placental transfer, and neonatal exposure in cynomolgus macaques (Macaca fascicularis). Teratology, 50, 148-159. https://doi.org/10.1002/tera.1420500209
- Takahashi, M., Shibutani, M., Nakahigashi, J., Sakaguchi, N., Inoue, K., Morikawa, T., Yoshida, M. and Nishikawa, A. (2009) Limited lactational transfer of acrylamide to rat offspring on maternal oral administration during the gestation and lactation periods. Arch. Toxicol., 83, 785-793. https://doi.org/10.1007/s00204-009-0418-y
- Doerge, D.R., Vanlandingham, M., Twaddle, N.C. and Delclos, K.B. (2010) Lactational transfer of bisphenol A in Sprague- Dawley rats. Toxicol. Lett., 199, 372-376. https://doi.org/10.1016/j.toxlet.2010.09.022
- Hendrickx, A.G., Nau, H., Binkerd, P., Rowland, J.M., Rowland, J.R., Cukierski, M.J. and Cukierski, M.A. (1988) Valproic acid developmental toxicity and pharmacokinetics in the rhesus monkey: an interspecies comparison. Teratology, 38, 329-345. https://doi.org/10.1002/tera.1420380405
- Nau, H. (1986) Species differences in pharmacokinetics and drug teratogenesis. Environ. Health Perspect., 70, 113-129. https://doi.org/10.1289/ehp.8670113
- Brown, N.A. and Fabro, S. (1983) The value of animal teratogenicity testing for predicting human risk. Chin. Obstet. Gynecol., 26, 467-477.
- Mast, T.J., Hendrickx, A.G. and Nau, H. (1985) Teratology and pharmacokinetics of valproic acid in the rhesus monkey. Teratology, 31, 25A.
- Neubert, D. and Chahoud, I. (1985) Significance of species and strain differences in pre- and perinatal toxicology. Arch. Histochem. Suppl., 31, 23-35.
- Schardein, J.L., Schwetz, B.A. and Kenel, M.F. (1985) Species sensitivities and prediction of teratogenic potential. Environ. Health Perspect., 61, 55-67
- Ornoy, A. (2009) Valproic acid in pregnancy: how much are we endangering the embryo and fetus? Reprod.Toxicol., 28, 1-10. https://doi.org/10.1016/j.reprotox.2009.02.014
- Jeong, E.J., Yu, W.J., Kim, C.Y. and Chung, M.K. (2010) Placenta transfer and toxicokinetics of valproic acid in pregnant cynomolgus monkeys. Toxicol. Res., 26, 275-283. https://doi.org/10.5487/TR.2010.26.4.275
- Dickinson, R.G., Lawyer, C.H., Kaufman, S.N., Lynn, R.K., Gerber, N., Novy, M.J. and Cook, M.J. (1980a) Maternofetal pharmacokinetics and fetal distribution of valproic acid in the pregnant rhesus monkey. Pediatr. Pharmacol., 1, 71-83
- Dickinson, R.G., Taylor, S.M., Kaufman, S.N., Rodgers, R.M., Lynn, R.K., Gerber, N. and Baughman, W.L. (1980b) Nonlinear elimination and choleretic effect of VPA in the monkey. J. Pharmacol. Exp. Ther., 213, 38-48.
- Ludden, T.M. (1991) Nonlinear pharmacokinetics: clinical implicantions. Clin. Pharmacokinet., 20, 429-446. https://doi.org/10.2165/00003088-199120060-00001
- Rettenmeier, A.W., Gordon, W.P., Prickett, K.S., Levy, R.H. and Baillie, T.A. (1986a) Biotransformation and pharmacokinetics in the rhesus monkey of 2-n-propyl-4-pentenoic acid, a toxic metabolite of valproic acid. Drug Metab. Dispos., 14, 454-464.
- Rettenmeier, A.W., Gordon, W.P., Prickett, K.S., Levy, R.H., Lockard, J.S., Thummel, K.E. and Baillie, T.A. (1986b) Metabolic fate of valproic acid in the rhesus monkey. Formation of a toxic metabolite, 2-n-propyl-4-pentenoic acid. Drug Metab. Dispos., 14, 443-453.
- Bennett, P.N. (1988) Drugs and human lactation. Elsevier, New York, pp. 341-342.
- von Unruh, G.E., Froescher, W., Hoffmann, F. and Niesen, M. (1984) Valproic acid in breast milk: how much is really there? Ther. Drug Monit., 6, 272-276 https://doi.org/10.1097/00007691-198409000-00003
- Albani, F., Riva, R., Contin, M., Baruzzi, A., Altomare, M., Merlini, G.P. and Perucca, E. (1984) Differential transplantal binding of valproic acid: influence of free fatty acids. Br. J. Clin. Pharmacol., 17, 759-762. https://doi.org/10.1111/j.1365-2125.1984.tb02414.x
- Tsuru, N., Maeda, T. and Tsuruoka, M. (1988) Three cases of delivery under sodium valproate-placental transfer, milk transfer and probable teratogenecity of sodium valproate. Jpn. J. Psychiatry Neurol., 42, 89-96.