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조영증강검사 시 생체 요인을 이용한 조영제 peak time에 관한 연구

A study of contrast agent peak time using biomechanics factors experimental contrast medium infusion test using at contrast enhanced magnetic resonance angiography

  • 손순룡 (한양대학교 대학원 보건학과) ;
  • 김윤신 (한양대학교 대학원 보건학과) ;
  • 최관우 (서울아산병원 영상의학과) ;
  • 서성미 (서울아산병원 영상의학과) ;
  • 민정환 (신구대학교 방사선과) ;
  • 유병규 (원광보건대학교 방사선과) ;
  • 이종석 (원광보건대학교 방사선과)
  • Son, Soon-Yong (Department of Health Science, Graduate School Hanyang University) ;
  • Kim, Yoon-Shin (Department of Health Science, Graduate School Hanyang University) ;
  • Choi, Kwan-Woo (Department of Radiology, Asan Medical Center) ;
  • Seo, Sung-Mi (Department of Radiology, Asan Medical Center) ;
  • Min, Jung-Whan (Department of Radiology, Shin-Gu University) ;
  • Yoo, Beong-Gyu (Department of Radiotechnology, Wonkwang Health Science University) ;
  • Lee, Jong-Seok (Department of Radiotechnology, Wonkwang Health Science University)
  • 투고 : 2012.11.16
  • 심사 : 2013.02.06
  • 발행 : 2013.02.28

초록

본 연구는 조영제 peak time에 영향을 주는 주된 생체 요인를 분석하여 검사에 적용함으로써 추가적인 조영제 주입에 따른 부작용을 최소화 하고 고해상도의 혈관영상을 유지하는 방안을 모색하고자 하였다. 시험적조영제주입법을 이용한 48명의 환자를 대상으로, 검사 전과 검사 중 환자의 생체 요인을 측정한 후, 조영제 peak time과 상관관계를 알아보고, 회귀식을 이용해 산출한 조영제 peak time이 측정된 조영제 peak time과 일치하는지 Bland-Altman plot를 통해 평가하였다. 연구결과, 검사 시 최저혈압과 심박동수가 조영제 peak time과 유의한 음의 상관관계를 보였고, 1단계 증가할 때마다 평균적으로 조영제 peak time은 -0.018과 -0.159로 유의하게 감소하였으며, 일치도가 상당히 높아 두 방법의 차이가 없음을 알 수 있다. 결론적으로 본 연구의 회귀식을 이용하면 우수한 화질을 유지하면서 환자에게 투여되는 조영제 사용량을 줄일 수 있어 기존의 방법을 대체할 수 있으리라 사료된다.

In this study was explored minimize side effects due to the additional injection of contrast medium and maintaining a high resolution imaging applied to the inspection and analysis of the contrast medium that affect the peak time biomechanics factors. Included 48 patients using the test bolus method, after measuring a patient's biomechanics factors of inspection before and during the test, correlation between contrast medium peak time and learn, matches the regression equation calculated and measured contrast medium peak time was assessed by the Bland Altman plot. Research result, inspections of SBP, HR contrast medium peak time and a significant negative correlation was, step 1, every increase, the contrast medium peak time significantly to -0.018 and -0.159 decreased, a fairly high concordance no difference between the two method. In conclusion, the regression equation using the existing methods, while maintaining excellent image quality that contrast medium is reduced to a patient, it can conclude that the alternative to the existing methods.

키워드

참고문헌

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피인용 문헌

  1. Evaluation of the signal intensity of magnetic resonance angiography in accordance with the dilution rate of the contrast agent vol.15, pp.8, 2014, https://doi.org/10.5762/KAIS.2014.15.8.5124