Biomaterials Research (생체재료학회지)

Korean Society for Biomaterials (한국생체재료학회)
권호 표지

Application of Growth Factors in Tissue Regeneration

조직재생을 위한 효과적인 성장인자의 활용

  • Yun, Ye-Rang (Institute of Tissue Regeneration Engineering (ITREN), Dankook University) ;
  • Kim, Hae-Won (Institute of Tissue Regeneration Engineering (ITREN), Dankook University) ;
  • Jang, Jun-Hyeog (Department of Biochemistry, Inha University School of Medicine)
  • 윤예랑 (단국대학교 조직공학연구소) ;
  • 김해원 (단국대학교 조직공학연구소) ;
  • 장준혁 (인하대학교 의과대학 생화학교실)
  • Received : 2013.07.19
  • Accepted : 2013.08.08
  • Published : 2013.12.01
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Abstract

Growth factors (GFs) are soluble-secreted signaling proteins capable of instructing specific cellular responses including cellular growth, proliferation, migration and differentiation. GFs are expected to be effective in tissue regeneration. However, due to the short biological half-life, lack of long-term stability and possible toxicity, GFs show the limitation on practical application. Currently, sophisticated biomaterials systems that control the biological release of growth factors represent a new strategy for tissue regeneration. Here, we introduce the functions of GFs and the combinational applications of GFs and biomaterials.

Keywords

Acknowledgement

Supported by : 한국연구재단

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