Pediatric Gastroenterology, Hepatology & Nutrition

  • 제16권4호
  • /
  • Pages.254-260
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  • 2013
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  • 2234-8646(pISSN)
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  • 2234-8840(eISSN)
대한소아소화기영양학회 (The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition)
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Subclinical Vitamin D Insufficiency in Korean School-aged Children

  • Han, Sang Woo (Department of Pediatrics, Eulji General Hospital) ;
  • Kang, Ha Ra (Department of Pediatrics, Eulji General Hospital) ;
  • Kim, Han Gyum (Department of Medicine, Eulji University) ;
  • Kim, Joo Hyun (Department of Medicine, Eulji University) ;
  • Uhm, Ji Hyun (Department of Pediatrics, Eulji General Hospital) ;
  • Seo, Ji Young (Department of Pediatrics, Eulji General Hospital)
  • 투고 : 2013.09.26
  • 심사 : 2013.10.29
  • 발행 : 2013.12.30
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초록

Purpose: Recently, vitamin D insufficiency has increased and has been correlated to growth and puberty in children. This study was conducted to find the prevalence of subclinical vitamin D insufficiency and its influence on school-aged children in Korea. Methods: The subjects of this study were 397 children aged 7 to 15 years who had been tested for 25-OH vitamin D3 among the outpatients of the Department of Pediatrics in Eulji General Hospital from March 2007 to February 2011. Data for age, sex, comorbidities, serum 25-OH vitamin D3, height, weight, body mass index (BMI), and sunlight exposure time were collected before and after 3 months of vitamin D administration, retrospectively. Results: Vitamin D insufficiency was present in 343 (86%) of the subjects. In the vitamin D insufficient group, chronological age was $8.96{\pm}1.72$ years, mean height (z-score [z]) was $0.51{\pm}1.26$, mean BMI (z) was $0.81{\pm}2.20$, and bone age was $10.26{\pm}1.75$ years. In the vitamin D sufficient group, chronological age was $9.61{\pm}1.77$ years, mean height (z) was -$0.66{\pm}0.98$, mean BMI (z) was -$0.01{\pm}1.16$, and bone age was $9.44{\pm}2.12$ years. A paired t-test showed that three months after vitamin D administration, the mean 25-OH vitamin D3 level in the insufficient group increased to $24.38{\pm}10.03$ ng/mL and mean BMI (z) decreased to $0.67{\pm}1.06$. Conclusion: In Korean school-aged children, vitamin D insufficiency were relatively higher and may be closely related with higher BMI. Insufficient rise of the level of vitamin D after supplementation suggest the new supplementation guidelines, especially for Korean children.

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참고문헌

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