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Irreversible Hemorrhagic Complication of Recurrent Posterior Reversible Encephalopathy Syndrome in a Patient with Systemic Lupus Erythematosus

전신성 홍반성 낭창 환자에서 재발한 가역적 후두부 뇌병증 증후군의 비가역적 출혈성 합병증

  • Kim, Ho Kyun (Department of Radiology, Catholic University of Daegu School of Medicine) ;
  • Lee, Hui Joong (Department of Radiology, Kyungpook National University Hospital) ;
  • Shin, Kyung Min (Department of Radiology, Kyungpook National University, School of Medicine)
  • 김호균 (대구가톨릭대학교 의과대학 영상의학과) ;
  • 이희중 (경북대학교병원 영상의학과) ;
  • 신경민 (경북대학교 의학전문대학원 영상의학과)
  • Received : 2012.11.01
  • Accepted : 2013.01.17
  • Published : 2013.06.30

Abstract

Although most cases of posterior reversible encephalopathy syndrome (PRES) are reversible, irreversible lesions as a form of hemorrhage or infarction have been described. PRES as a complication of systemic lupus erythematosus (PRES-SLE) is associated with hypertension or use of immunosuppressive agents. We present a case of recurrent atypical PRES-SLE, which showed restricted diffusion in the first manifestation of SLE, resulted in parenchymal hemorrhagic transformations in the recurrent episode.

대부분의 가역적 후두부 뇌병증 증후군 (PRES)는 가역적인 경과를 보이나 출혈 또는 경색을 동반한 비가역적 경과들도 보고되고 있다. 전신성 홍반성 낭창 (SLE)과 관련된 PRES는 고혈압이나 면역억제제와 관련이 있다. 저자들은 최초 PRES발병 시 확산강조영상에서 확산제한을 보인 부위에서, PRESS의 반복 발생 시 출혈성 변환을 보인 증례를 보고한다.

Keywords

References

  1. Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med 1996;334:494- 500 https://doi.org/10.1056/NEJM199602223340803
  2. Kinoshita T, Moritani T, Shrier DA, et al. Diffusion-weighted MR imaging of posterior reversible leukoencephalopathy syndrome: a pictorial essay. Clin Imaging 2003;27:307-315 https://doi.org/10.1016/S0899-7071(02)00592-2
  3. McKinney AM, Short J, Truwit CL, et al. Posterior reversible encephalopathy syndrome: incidence of atypical regions of involvement and imaging findings. AJR Am J Roentgenol 2007;189:904-912 https://doi.org/10.2214/AJR.07.2024
  4. Magnano MD, Bush TM, Herrera I, Altman RD. Reversible posterior leukoencephalopathy in patients with systemic lupus erythematosus. Semin Arthritis Rheum 2006;35:396-402 https://doi.org/10.1016/j.semarthrit.2006.01.002
  5. Provenzale JM, Petrella JR, Cruz LC, Wong JC, Engelter S, Barboriak DP. Quantitative assessment of diffusion abnormalities in posterior reversible encephalopathy syndrome. AJNR Am J Neuroradiol 2001;22:1455-1461
  6. Covarrubias DJ, Luetmer PH, Campeau NG. Posterior reversible encephalopathy syndrome: prognostic utility of quantitative diffusion-weighted MR images. AJNR Am J Neuroradiol 2002;23:1038-1048
  7. Bartynski WS. Posterior reversible encephalopathy syndrome, part 2: controversies surrounding pathophysiology of vasogenic edema. AJNR Am J Neuroradiol 2008;29:1043-1049 https://doi.org/10.3174/ajnr.A0929
  8. Sweany JM, Bartynski WS, Boardman JF. "Recurrent" posterior reversible encephalopathy syndrome: report of 3 cases--pres can strike twice! J Comput Assist Tomogr 2007;31: 148-156 https://doi.org/10.1097/01.rct.0000233127.21303.b9
  9. Thaipisuttikul I, Phanthumchinda K. Recurrent reversible posterior leukoencephalopathy in a patient with systemic lupus erythematosus. J Neurol 2005;252:230-231 https://doi.org/10.1007/s00415-005-0613-6
  10. Lee VH, Wijdicks EF, Manno EM, Rabinstein AA. Clinical spectrum of reversible posterior leukoencephalopathy syndrome. Arch Neurol 2008;65:205-210