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Necessity for a National Carcinogen List in Korea, Based on International Harmonization

  • Leem, Jong Han (Department of Occupational and Environmental Medicine, Inha University School of Medicine) ;
  • Kim, Hwan Cheol (Department of Occupational and Environmental Medicine, Inha University School of Medicine) ;
  • Park, Myungsook (Department of Social and Preventive Medicine, Inha University School of Medicine) ;
  • Kim, Jung Ae (Department of Social and Preventive Medicine, Inha University School of Medicine) ;
  • Kim, Shin-Bum (Wonjin Institute of Occupational and Environmental Health) ;
  • Ha, Mina (Department of Preventive Medicine, Dankook University College of Medicine) ;
  • Lim, Min-Kyeong (Cancer Risk Appraisal and Prevention Branch, National Cancer Information Center, National Cancer Center) ;
  • Kim, Jeongseon (Molecular Epidemiology Branch, National Cancer Center) ;
  • Park, Eun Young (Cancer Information and Education Branch, National Cancer Information Center, National Cancer Center) ;
  • Paek, Domyung (School of Public Health and Institute of Health and Environment, Seoul National University)
  • Received : 2012.06.30
  • Accepted : 2013.05.01
  • Published : 2013.01.02

Abstract

Cancer has been the leading cause of death in Korea for the last 30 years. Cancer patients' 5-year survival rate between 2005 and 2009 was 62.0%, representing a highly advanced standard of care, as much as developed countries in the EU and the US. The Korean government formulated its first 10-year plan for cancer control in 1996 and has been carrying out a second 10-year plan for cancer control since 2006. But despite the Korean government's efforts, the cancer burden in Korea continues to increase. Many separate laws have gone into effect concerning the management of carcinogen exposure. However, there are no integrated regulatory laws or management systems against carcinogen exposure in Korea. Dead zones remain where carcinogen exposure cannot be controlled properly in Korea. In this paper, we suggest the need to establish a national carcinogen list based on international harmonization as a prerequisite for a paradigm shift in cancer control policy from treatment to primary prevention.

Keywords

References

  1. Yoo KY. Cancer control activities in the Republic of Korea. Jpn J Clin Oncol 2008;38(5):327-333. https://doi.org/10.1093/jjco/hyn026
  2. National Cancer Information Center. Common cancer sites in Korea [cited 2013 Mar 11]. Available from: http://www.cancer.go.kr/ mbs/cancer/subview.jsp?id=cancer_040102000000 (Korean).
  3. Korea Centers for Disease Control and Prevention. Korean National Health and Nutrition Examination Survey: smoking rate in Korea [cited 2012 Jun 23]. Available from: http://knhanes.cdc.go. kr/knhanes/index.do (Korean).
  4. Shin A, Park S, Shin HR, Park EH, Park SK, Oh JK, et al. Population attributable fraction of infection-related cancers in Korea. Ann Oncol 2011;22(6):1435-1442. https://doi.org/10.1093/annonc/mdq592
  5. Leem JH, Kim HC, Ryu JS, Won JU, Moon JD, Kim YC, et al. Occupational lung cancer surveillance in Korea, 2006-2009. Saf Health Work 2010;1(2):134-139. https://doi.org/10.5491/SHAW.2010.1.2.134
  6. Son M. The burden of occupational cancer in Korea. Proceedings of the Great Autumn Academic Conference of Korean Society of Occupational & Environmental Medicine; 2012 Nov 8-10; Byeonsan, Korea. Seoul: Korean Society of Occupational & Environmental Medicine; 2012 (Korean).
  7. Park S. Attributable causes of cancer in Korea. Proceedings of the 63rd Conference of the Korean Society of Preventive Medicine; 2011 Oct 27-28; Cheongju, Korea. Seoul: Korean Society of Preventive Medicine; 2011 (Korean).
  8. International Agency for Research on Cancer. Attributable causes of cancer in France in the year 2000 [cited 2012 Jun 23]. Available from: http://www.iarc.fr/en/publications/pdfs-online/wrk/wrk3/ index.php.
  9. Yoon SJ. Measuring the burden of disease due to environmental risk factor. Gwacheon: Ministry of Environment; 2010, p. 1-138 (Korean).
  10. Korea Centers for Disease Control and Prevention. Korean National Health and Nutrition Examination Survey: passive smoking rate in Korea [cited 2012 Jun 23]. Available from: http://knhanes. cdc.go.kr/knhanes/index.do (Korean).
  11. Jee SH, Ohrr H, Kim IS. Effects of husbands' smoking on the incidence of lung cancer in Korean women. Int J Epidemiol 1999;28 (5):824-828. https://doi.org/10.1093/ije/28.5.824
  12. Kim HR. Overview of asbestos issues in Korea. J Korean Med Sci 2009;24(3):363-367. https://doi.org/10.3346/jkms.2009.24.3.363
  13. Stewart PA, Coble JB, Vermeulen R, Schleiff P, Blair A, Lubin J, et al. The diesel exhaust in miners study: I. Overview of the exposure assessment process. Ann Occup Hyg 2010;54(7):728-746. https://doi.org/10.1093/annhyg/meq022
  14. Coble JB, Stewart PA, Vermeulen R, Yereb D, Stanevich R, Blair A, et al. The Diesel Exhaust in Miners Study: II. Exposure monitoring surveys and development of exposure groups. Ann Occup Hyg 2010;54(7):747-761. https://doi.org/10.1093/annhyg/meq024
  15. Vermeulen R, Coble JB, Yereb D, Lubin JH, Blair A, Portengen L, et al. The Diesel Exhaust in Miners Study: III. Interrelations between respirable elemental carbon and gaseous and particulate components of diesel exhaust derived from area sampling in underground non-metal mining facilities. Ann Occup Hyg 2010;54(7): 762-773. https://doi.org/10.1093/annhyg/meq023
  16. Leem JH, Kim HC, Kim SB, Ha M, Lim MK, Kim JS, et al. Study on current status of carcinogen and effective policy intervention in Korea. Seoul: Ministry of Health and Welfare; 2012, p. 141-150 (Korean).
  17. Lee YK. First compensation case for breast cancer in a shiftwork laborer. Kyunghyang Shinmun; 2012 Dec 14 [cited 2013 Mar 11]. Available from: http://news.khan.co.kr/kh_news/khan_art_view. html?artid=201212142138565&code=940702 (Korean).
  18. International Agency for Research on Cancer. IARC classifies radiofrequency electromagnetic fields as possibly carcinogenic to humans; 2011 [cited 2013 Apr 4]. Available from: http://www.iarc. fr/en/media-centre/pr/2011/pdfs/pr208_E.pdf.
  19. International Agency for Research on Cancer. IARC: diesel engine exhaust carcinogenic; 2012 [cited 2012 Jun 23]. Availabe from: http://www.iarc.fr/en/media-centre/pr/2012/pdfs/pr213_E.pdf.
  20. World Health Organization. 58th World Health Assembly approved resolution on cancer prevention and control [cited 2012 Jun 23]. Available from: http://www.who.int/cancer/eb1143/en/.
  21. International Agency for Research on Cancer. IARC monographs on the evaluation of carcinogenic risks to humans [cited 2013 Mar 4]. Available from: http://monographs.iarc.fr/index.php.
  22. Cogliano VJ. The IARC Monographs: a resource for precaution and prevention. Occup Environ Med 2007;64(9):572. https://doi.org/10.1136/oem.2006.031872
  23. Collingridge D. Increased transparency in IARC Monograph programme. Lancet Oncol 2005;6(10):735. https://doi.org/10.1016/S1470-2045(05)70364-8
  24. Blainey M, Holmqvist J. Classification, labelling and packaging: implementation of the globally harmonised system. J Eur Environ Plan Law 2008;5(1)69-95.
  25. European Parliament. Directive 1999/45/EC of the European Parliament and of the Council of 31 May 1999 concerning the approximation of the laws, regulations and administrative provisions of the Member States relating to the classification, packaging and labelling of dangerous preparations [cited 2012 Jun 23]. Available from: http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri= CELEX:31999L0045:en:NOT.
  26. European Parliament. Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/ EC, and amending Regulation (EC) No 1907/2006 [cited 2012 Jun 23]. Available from: http://eur-lex.europa.eu/LexUriServ/ LexUriServ.do?uri=OJ:L:2008:353:0001:1355:en:PDF.
  27. Rodu B, Cole P, Mandel JS. Evaluation of the national toxicology program report on carcinogens. Regul Toxicol Pharmacol 2012;64 (1):186-188. https://doi.org/10.1016/j.yrtph.2012.07.002
  28. Huff J, Haseman J. Long-term chemical carcinogenesis experiments for identifying potential human cancer hazards: collective database of the National Cancer Institute and National Toxicology Program (1976-1991). Environ Health Perspect 1991;96:23-31. https://doi.org/10.1289/ehp.919623
  29. Huff J. Carcinogenesis bioassay results from the National Toxicology Program. Environ Health Perspect 1982;45:185-198. https://doi.org/10.1289/ehp.8245185
  30. International Agency for Research on Cancer. Agents classified by the IARC monographs, volumes 1-107; 2012 [cited 2012 Dec 17]. Available from: http://monographs.iarc.fr/ENG/Classification/.
  31. American Conference of Governmental Industrial Hygienists. 2010 TLVs and BEIs: based on the documentation of the threshold limit values for chemical substances and physical agents & biological exposure indices. Cincinnati, OH: ACGIH Signature Publications; 2010. p. 73-74.
  32. Institute for Health and Consumer Protection. Table 3.1 and Table 3,2 of Annex VI to the CLP regulation, as updated with the 1st ATP; 2012 [cited 2013 Apr 29]. Available from: http://esis.jrc. ec.europa.eu/index.php?PGM=cla.
  33. National Toxicology Program. 12th report on carcinogens; 2011 [cited 2012 Jun 23]. Available from: http://ntp.niehs.nih.gov/ntp/ roc/twelfth/roc12.pdf.
  34. Kim PJ. Carcinogen assessment: management in Toxic Chemical Control Act and future perspective. Forum for Cancer Control; 2012 Mar 9; Seoul, Korea. Incheon: National Institute of Environment Research; 2012 (Korean).