Journal of Digital Convergence (디지털융복합연구)

The Society of Digital Policy and Management (한국디지털정책학회)
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Relationship Between Oral Contraceptive Use and Periodontal Disease in Korean Women

제4기 국민건강영양조사 자료에 근거한 한국 여성의 경구피임약 복용과 치주질환의 관련성

  • Kim, Ki-Rim (Oral Cancer Research Institute, Yonsei University College of Dentistry) ;
  • Noh, Hie-Jin (Department of Dental Hygiene, Kangwon National University College of Health Science)
  • 김기림 (연세대학교 치과대학 구강종양연구소) ;
  • 노희진 (강원대학교 보건과학대학 치위생학과)
  • Received : 2013.10.24
  • Accepted : 2013.12.20
  • Published : 2013.12.28
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Abstract

This study aims to evaluate the influence of oral contraceptive(OC) on periodontal disease. Research data was used the results derived from the Fourth Korean National Health and Nutrition Examination Survey(KNHANES), and 1,101 Korean women, aged 19 to 50 years with non-pregnant and premenopausal, were selected. The chi-square test and logistic regression analysis were performed to identify the relationship between OC use and periodontal disease, according to factors of demographic and socioeconomic, oral health behavior, OC use period, and periodontal status. In the results, OC use was statistically related with age, marital status and smoking. No significant differences were found in between the gingival condition and current OC use. The prevalence of periodontal disease increased with age, but did not have significant correlations with period of OC usage, smoking and oral health behavior. Final analysis was indicated that OC use is not associated with periodontal disease, regardless of adjustment for confounding variables.

본 연구는 우리나라 여성을 대상으로 경구피임약 복용과 치주질환의 관련성을 분석하여 피임약이 치주질환에 미치는 영향을 파악하고자 하였다. 연구자료는 제4기 국민건강영양조사 자료 중 2008년과 2009년 결과를 이용하였고, 19-50세 폐경 전 가임여성 1,101명을 대상자로 선정하였다. 인구사회경제적 요인과 구강보건행태, 피임약 복용기간 및 치주질환 상태를 파악하여 chi-square 검정과 logistic regression 분석을 통해 경구피임약 복용과 치주질환과의 관련성을 조사하였다. 그 결과, 인구사회경제적 요인 중 연령과 결혼여부, 흡연상태가 경구피임약 복용과 통계적인 유의성을 나타내었다. 현재 경구피임약 복용여부와 치은조직 상태는 연관성이 없는 것으로 확인되었다. 치주질환 유병율은 연령에 따라 증가하였지만, 피임약 복용기간과 흡연, 칫솔질과 치간관리를 포함한 구강보건형태와는 통계적으로 유의한 차이를 보이지 않았다. 마지막으로 logistic regression 분석 결과, 혼란변수 보정여부에 따라 큰 차이 없이 치주질환은 경구피임약 복용여부 및 복용기간과 관련성이 없는 것으로 확인되었다.

Keywords

References

  1. Thorneycroft, I.H., et al., Effect of low-dose oral contraceptives on androgenic markers and acne. Contraception, 60(5): p. 255-62. 1999. https://doi.org/10.1016/S0010-7824(99)00093-1
  2. Hannaford, P.C., et al., Cancer risk among users of oral contraceptives: cohort data from the Royal College of General Practitioner's oral contraception study. Bmj, 335(7621): p. 651, 2007. https://doi.org/10.1136/bmj.39289.649410.55
  3. Wong, C.L., et al., Oral contraceptive pill as treatment for primary dysmenorrhoea. Cochrane Database Syst Rev, 2009(2): p. Cd002120, 2009.
  4. Schindler, A.E., Non-contraceptive benefits of oral hormonal contraceptives. Int J Endocrinol Metab, 11(1): p. 41-7, 2013.
  5. Gierisch, J.M., et al., Oral Contraceptive Use and Risk of Breast, Cervical, Colorectal, and Endometrial Cancers: A Systematic Review. Cancer Epidemiol Biomarkers Prev, 2013.
  6. Hee, L., L.O. Kettner, and M. Vejtorp, Continuous use of oral contraceptives: an overview of effects and side-effects. Acta Obstet Gynecol Scand, 92(2): p. 125-36, 2013. https://doi.org/10.1111/aogs.12036
  7. Musajo, F., et al., [Estradiol hormone receptors in human gingiva: preliminary results]. G Stomatol Ortognatodonzia, 3(1): p. 75-9, 1985.
  8. Mariotti, A., Sex steroid hormones and cell dynamics in the periodontium. Crit Rev Oral Biol, Med, 5(1): p. 27-53, 1994. https://doi.org/10.1177/10454411940050010201
  9. Parkar, M.H., H.N. Newman, and I. Olsen, Polymerase chain reaction analysis of oestrogen and androgen receptor expression in human gingival and periodontal tissue. Arch Oral Biol, 41(10): p. 979-83, 1996. https://doi.org/10.1016/S0003-9969(96)00053-2
  10. Preshaw, P.M., M.A. Knutsen, and A. Mariotti, Experimental gingivitis in women using oral contraceptives. J Dent Res, 80(11): p. 2011-5, 2001. https://doi.org/10.1177/00220345010800111201
  11. Taichman, L.S. and S.A. Eklund, Oral contraceptives and periodontal diseases: rethinking the association based upon analysis of National Health and Nutrition Examination Survey data. J Periodontol, 76(8): p. 1374-85, 2005. https://doi.org/10.1902/jop.2005.76.8.1374
  12. Preshaw, P.M., Oral contraceptives and the periodontium. Periodontol 2000, 61(1): p. 125-59, 2013. https://doi.org/10.1111/j.1600-0757.2011.00399.x
  13. Han, S.B., H.S. Moon, and H.J. Lee, [Epidemiological study of periodontal disease in rural Korea]. Taehan Chikkwa Uisa Hyophoe Chi, 24(10): p. 893-900, 1986.
  14. Abdellatif, H.M. and B.A. Burt, An epidemiological investigation into the relative importance of age and oral hygiene status as determinants of periodontitis. J Dent Res, 66(1): p. 13-8, 1987. https://doi.org/10.1177/00220345870660010201
  15. Haber, J., Cigarette smoking: a major risk factor for periodontitis. Compendium, 15(8): p. 1002, 1004-8, 1994.
  16. Moimaz, S.A., et al., Smoking and periodontal disease: clinical evidence for an association. Oral Health Prev Dent, 7(4): p. 369-76, 2009.
  17. Rheu, G.B., et al., Risk assessment for clinical attachment loss of periodontal tissue in Korean adults. J Adv Prosthodont, 3(1): p. 25-32, 2011. https://doi.org/10.4047/jap.2011.3.1.25
  18. Huppert, L.C., Vascular effects of hormonal contraception. Clin Obstet Gynecol, 1981. 24(3): p. 951-63. https://doi.org/10.1097/00003081-198109000-00020
  19. Goldzieher, J.W., Hormonal contraceptives. Past, present, and future. Postgrad Med, 75(5): p. 75-7, 80, 83-6, 1984. https://doi.org/10.1080/00325481.1984.11697991
  20. Goldzieher, J.W., Hormonal contraception: benefits versus risks. Am J Obstet Gynecol, 157(4 Pt 2): p. 1023-8, 1987. https://doi.org/10.1016/S0002-9378(87)80127-8
  21. Williams CL, S.G., Estrogens and progestins, in Goodman & Gilman's The Pharmacological basis of therapeutics. L.L. Hardman JG, Editor, New York: McGraw-Hill, p. 1411-1441, 1996.
  22. Lindhe, J. and A.L. Bjorn, Influence of hormonal contraceptives on the gingiva of women. J Periodontal Res, 2(1): p. 1-6, 1967. https://doi.org/10.1111/j.1600-0765.1967.tb01989.x
  23. Knight, G.M. and A.B. Wade, The effects of hormonal contraceptives on the human periodontium. J Periodontal Res, 9(1): p. 18-22, 1974. https://doi.org/10.1111/j.1600-0765.1974.tb00648.x
  24. Locker, D., G.D. Slade, and H. Murray, Epidemiology of periodontal disease among older adults: a review. Periodontol 2000, 16: p. 16-33, 1998. https://doi.org/10.1111/j.1600-0757.1998.tb00113.x
  25. Albandar, J.M., Epidemiology and risk factors of periodontal diseases. Dent Clin North Am, 49(3): p. 517-32, 2005. https://doi.org/10.1016/j.cden.2005.03.003
  26. Stamm, J.W., Epidemiology of gingivitis. J Clin Periodontol, 13(5): p. 360-70, 1986. https://doi.org/10.1111/j.1600-051X.1986.tb01473.x
  27. Tilakaratne, A., et al., Effects of hormonal contraceptives on the periodontium, in a population of rural Sri-Lankan women. J Clin Periodontol, 27(10): p. 753-7, 2000. https://doi.org/10.1034/j.1600-051x.2000.027010753.x

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