Bulletin of the Korean Chemical Society

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Asymmetric Synthesis of (+)-trans-Aerangis Lactone

  • Received : 2012.09.10
  • Accepted : 2012.10.04
  • Published : 2013.01.20
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Abstract

Asymmetric synthesis of (+)-trans-aerangis lactone was achieved from commercially available 1-hexanol or 1-hexanal in four steps via iridium-catalyzed diastereoselective and enantioselective carbonyl crotylation from the alcohol or aldehyde oxidation level, and ruthenium-catalyzed olefin metathesis.

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