Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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Do Different Arterial Stiffness Parameters Provide Similar Information in High-Risk Patients for Coronary Artery Disease?

  • Kim, Kyung Min (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Yoo, Byung-Su (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Ko, Anna (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Kim, Jeong Min (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Kim, Hyun Sik (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Lee, Jun-Won (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Kim, Jang-Young (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Youn, Young Jin (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Ahn, Sung Gyun (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Lee, Seung-Hwan (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine) ;
  • Yoon, Junghan (Division of Cardiology, Department of Internal Medicine, Yonsei University Wonju College of Medicine)
  • Received : 2013.10.01
  • Accepted : 2013.11.05
  • Published : 2013.12.30
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Abstract

Background and Objectives: The aim of our study was to compare the values of brachial-ankle pulse wave velocity (baPWV) measured with two different non-invasive methods as predictors of coronary artery disease (CAD) in patients who had undergone coronary angiography. Subjects and Methods: From 6373 patients who visited our laboratory for non-invasive procedures, we enrolled 965 consecutive patients undergoing coronary angiography. Data for baPWV and peripheral augmentation index (pAI) were recorded. CAD was defined as greater than 50% stenosis of a major epicardial artery in a coronary angiogram. In addition, the severity of CAD was classified as: none/minimal or 1-, 2-, or 3-vessel disease, based on previous or current angiographic findings. Results: Among 965 subjects, the mean age was $63.7{\pm}11.6$ years, and 58.2% were male. Compared with subjects without CAD disease, those with CAD showed higher values of baPWV ($16.6{\pm}3.5$ m/sec vs. $15.9{\pm}3.4$ m/sec, p<0.001), and lower values of pAI ($73.5{\pm}15.9%$ vs. $76.0{\pm}15.7%$, p=0.01). When the severity of CAD was expressed as none/minimal or 1-, 2-, or 3-vessel disease, there was a significant association between the extent of CAD and baPWV (p<0.001). In univariate analysis, high PWV and low pAI were associated with an increased prevalence of CAD (p<0.001). Conclusion: Increased baPWV and decreased pAI were associated with the presence of CAD in the elderly.

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References

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