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Korean Society of Photoscience (한국광과학회)
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Microflow Photochemistry - Acetone sensitized Addition of Isopropanol to (5R)-5-Menthyloxy-2-(5H)-furanone

  • Aida, Shin (Nara Institute of Science and Technology (NAIST), Graduate School of Materials Science) ;
  • Nishiyama, Yasuhiro (Nara Institute of Science and Technology (NAIST), Graduate School of Materials Science) ;
  • Kakiuchi, Kiyomi (Nara Institute of Science and Technology (NAIST), Graduate School of Materials Science) ;
  • Hoffmann, Norbert (UMR 7312 CNRS et Universite de Reims Champagne-Ardenne, Institut de Chimie Moleculaire de Reims, UFR Sciences) ;
  • Fon, Adeline (James Cook University, School of Pharmacy and Molecular Sciences) ;
  • Oelgemoller, Michael (James Cook University, School of Pharmacy and Molecular Sciences)
  • Received : 2013.10.27
  • Accepted : 2013.11.22
  • Published : 2013.09.01
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Abstract

Acetone sensitized photoadditions of isopropanol to (5R)-5-menthyloxy-2-(5H)-furanone were investigated in two different microflow reactor systems. Setup A employed a commercially available glass reactor under a UVB-panel. Setup B utilized a FEP microcapillary wrapped tightly around a Pyrex cylinder with a single UVB fluorescent tube at its center. The reactions under flow conditions were subsequently compared to analogue reactions conducted in a batch chamber reactor. Overall, the microflow systems gave faster conversions and higher isolated yields. The flexible microcapillary setup, however, showed the best performance and promise in terms of future scale-up and reactor optimization.

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