Journal of Dental Rehabilitation and Applied Science (구강회복응용과학지)

Korean Academy of Stomatognathic Function and Occlusion (대한턱관절교합학회)
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Treatment of Snoring and Sleep Apnea with Botulinum Toxin

보툴리눔 독소를 이용한 코골이 및 수면무호흡 치료

  • Jang, Jae-Young (Department of Orofacial pain and Oral medicine, College of Dentistry, Yonsei University) ;
  • Chung, A-Young (Department of Orofacial pain and Oral medicine, College of Dentistry, Yonsei University) ;
  • Kim, Seong-Taek (Department of Orofacial pain and Oral medicine, College of Dentistry, Yonsei University)
  • 장재영 (연세대학교 구강내과학교실) ;
  • 정아영 (연세대학교 구강내과학교실) ;
  • 김성택 (연세대학교 구강내과학교실)
  • Received : 2013.06.20
  • Accepted : 2013.10.30
  • Published : 2013.12.31
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Abstract

Botulinum toxin has been used for treating strabismus, blepharospasm, cerebral palsy, cervical dystonia, hyperhydrosis, facial wrinkle and chronic migraine under US Food and Drug administration approval. Also it has been tried spasticity-induced pain, post-herpetic neuralgia, myofascial pain and aphthous ulcer as off-label use. In this study, we reviewed recent studies that suggested effects of botulinum toxin on snoring and sleep apnea.

보툴리눔 독소는 사시, 안검경련, 뇌성마비, 경부근 근육긴장이상, 다한증, 얼굴의 주름 같은 미용 치료, 그리고 만성 편두통 치료에 미국 식약청의 승인을 받아 사용되고 있다. 이외에도 강직유발 통증, 포진후 신경통, 근막통증, 아프타성 구내염 등과 같은 통증을 조절하는 데 효과가 있을 것이라 기대되어 다양한 의료영역에서 연구가 진행되고 있는데, 최근 코골이 및 수면무호흡 치료에 있어서 보툴리눔 독소의 효과에 관한 연구들이 보고된 바 있어 그 유용성에 관해 고찰해 보고자 한다.

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References

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