Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Mammary Comedocarcinoma in a Dog

개에서 발생한 유선 면포암종

  • Kim, Jae-Hoon (Gyeonggi-do Livestock and Veterinary Service) ;
  • Kim, Jae-Hoon (College of Veterinary Medicine and Veterinary Medical Research Institute, Jeju National University)
  • 김재훈 (경기도 축산위생연구소) ;
  • 김재훈 (제주대학교 수의과대학, 수의과학연구소)
  • Accepted : 2013.12.09
  • Published : 2013.12.31
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Abstract

An 18-year-old, neutered female, Yorkshire terrier was presented with abdominal mass. Large abdominal mass was located in right 4th and 5th mammary glands. Surgically excised mammary mass was submitted for histological evaluation. Microscopically, multifocal to confluent neoplastic foci were existed from superficial dermis to subcutis. Several different growth patterns such as comedo, solid, cribriform, and micropapillary were present in the neoplastic foci. Large neoplastic mammary ducts showed great invasive tendency to adjacent tissues. Many superficial lymphatic plexuses and dermal lymphatics contained numerous neoplastic cell emboli. Because comedo pattern was demonstrated by more than 50% of the neoplastic cell population, we confirmed this case as mammary comedocarcinoma according to recent classification of canine mammary tumors.

18세령 중성화 암컷 요크셔테리어종 개가 우측 4번 및 5번 유선 부위에 위치한 대형 복부 종괴로 내원하였다. 외과적으로 적출한 유선 종괴가 병리학적 진단을 위하여 의뢰되었다. 병리조직학적 소견으로 종괴는 표피에서 피하조직에 걸쳐 다발성 및 융합된 종양성 집락들로 구성되어 있었다. 종양성 집락들은 면포상, 고형상, 사상 및 미세유두상 등의 매우 다양한 형태를 나타내었으며, 큰 종양성 유선 도관은 주변조직으로의 강한 침습성을 나타내고 있었다. 진피표층에 위치한 다수의 림프관 얼기들과 진피의 림프관에는 무수히 많은 종양세포의 색전을 가지고 있었다. 종양을 구성하고 있는 세포들의 약 50%이상이 면포상의 형태를 띠고 있기 때문에, 본 증례는 최근의 개 유선 종양의 분류에 근거하여 개의 유선에서 발생한 유선 면포 암종으로 진단하였다.

Keywords

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