Journal of Environmental Science International (한국환경과학회지)

The Korean Environmental Sciences Society (한국환경과학회)
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Associations between Airborne Manganese and Blood Manganese in the Korean General Population according to KNHANES 2008-2009

한국인의 혈중 망간농도와 공기중 망간농도의 관련성

  • Jung, Kyung Sick (Institute of Environmental and Occupational Medicine, Soonchunhyang University) ;
  • Lee, Jong Dae (Environmental Health Research Center, Soonchunhyang University) ;
  • Kim, Yong Bae (Institute of Environmental and Occupational Medicine, Soonchunhyang University)
  • 정경식 (순천향대학교 환경산업의학연구소) ;
  • 이종대 (순천향대학교 환경보건센터) ;
  • 김용배 (순천향대학교 환경산업의학연구소)
  • Received : 2013.03.08
  • Accepted : 2013.07.10
  • Published : 2013.12.31
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Abstract

The objective of this study was to evaluate associations between airborne manganese and blood manganese in a general population of South Korean adults. The concentrations of airborne manganese in total suspended particulate (TSP) were calculated from data obtained from ambient air-monitoring stations (AAMSs) located in South Korea. Blood manganese data obtained Korean National Health and Nutrition Examination Survey (KNHANES) using a rolling sampling design involving a complex, stratified, multistage, probability cluster survey of a representative sample of the non-institutionalized civilian population of South Korea. Airborne manganese geometric means was 46.10 $ng/m^3$, blood manganese geometric means were 1.19 ${\mu}g/d{\ell}$ for male and 1.40 ${\mu}g/d{\ell}$ for female. In multiple linear regression analysis of log transformed blood manganeseas a continuous variable on airborne manganese, after adjusting for covariates including gender, age, job, smoking and drinking status, education level, BMI (body mass index). Airborne manganese was positively associated with blood manganese with statistical significance. The present study confirms that airborne manganese is a possible contributor to the increase of blood manganese in the adult general population.

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References

  1. Alves, G., Muller, B., Herlofson, K., Hogenesch, I., Telstad, W., Aarsland, D., Tysnes, O. B., Larsen, J. P., 2009, Incidence of Parkinson's disease in Norway: the Norwegian ParkWest study, J. Neurol. Neurosurg. Psychiatry., 80, 851-857. https://doi.org/10.1136/jnnp.2008.168211
  2. ATSDR, Toxicological Profile for Manganese, 2000, U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, Atlanta, America.
  3. ATSDR, Toxicological profile for manganese, 2012, U.S. Department of Health and Human Services, Agency for Toxic Substances and Disease Registry, Atlanta, America.
  4. Brunekreef, B., Holgate, S. T., 2002, Air pollution and health, Lancet., 360, 1233-1242. https://doi.org/10.1016/S0140-6736(02)11274-8
  5. Centers for Disease Control and Prevention(CDC), 2010, The fourth Korea National Health and Nutrition Examination Survey, 2009 Health Examination, Atlanta, America.
  6. Finley, J. W., 1999, Manganese absorption and retention by young women is associated with serum ferritin concentration, Am. J. Clin. Nutr., 70, 37-43.
  7. Choi, H. C., Kim, K. Y., An, S. H., Hyun, D. W., 1998, Manganese Concentration in Blood and Urine of Manganese Exposed Welding Workers, Korea. J. Occup. Environ. Med., 10(4), 534-547.
  8. Choi, M. H., Kim, E. Y., 2007, Evaluation of Dietary Manganese Intake in Korean Men and Women over 20 Years Old, J. Korean. Soc. Food. Sci. Nutr., 36(4), 447-452. https://doi.org/10.3746/jkfn.2007.36.4.447
  9. Finely, J. W., Johnson, P. E., Johnson, L. K., 1994. Sex affects manganese absorption and retention by human from diet adequate in manganese, Am. J. Clin. Nutr., 60, 649-955.
  10. Finkelstein, M. M., Jerrett, M., 2007, A study of the relationship between Parkin- son's disease and markers of traffic-derived and environmental manganese air pollution in two Canadian cities, Environmental. Research., 104, 420-432. https://doi.org/10.1016/j.envres.2007.03.002
  11. Haynes, E. N., Ryan, P., Chen, A., Brown, D., Roda, S., Kuhnell, P., Wittberg, D., Terrell, M., Reponen, T., 2012, Assessment of personal exposure to manganese in children living near a ferromanganese refinery, Sci. Total. Environ., 15, 427-428.
  12. Iregren, A., 1990, Psychological test performance in foundry workers exposed to low levels of manganese, Neurotoxicol. Teratol., 12(6), 673-675. https://doi.org/10.1016/0892-0362(90)90085-Q
  13. Kampa, M., Castanas, E., 2008, Human health effects of air pollution, Environmental. Pollution., 51, 362-367.
  14. Kim, K. S., Kim, Y. H., Jin, Y. W., Kin, E. U., Yang, J. S., Kwon K. R., Kim, J. W., Roh, J. H., Moon, Y. H., 1999, Factors Associated with Psychoneurobehaviral Outcomes in Workers Exposed to Manganese, Korea. J. Occup. Environ. Med., 11(2), 213-228.
  15. Kim, Y. H., 2009, Health Effects of Manganese and Some Recent Issues in Manganese Neurotoxicity Research, Korea. J. Occup. Environ. Med., 21(1), 87-105.
  16. Kim, Y. H., Lee, B. K., 2011, Iron deficiency increases blood manganese level in the Korean general population according to KNHANES 2008, Neurotoxicology., 32, 247-254. https://doi.org/10.1016/j.neuro.2010.12.006
  17. Lee, B. K., Kim, Y. H., 2011, Relationship between blood manganese and blood pressure in the Korean general population according to KNHANES 2008, Environmental. Research., 111, 797-803. https://doi.org/10.1016/j.envres.2011.05.005
  18. Lee, K. S., Paik, N. W., 1994, Airborne Concentrations of Welding Fume and Metal Components by Type of Welding, Korea. Ind. Hyg. Assoc. J., 4(1), 71-80.
  19. Levy, B. S., Nassetta, W. J., 2003, Neurologic effects of manganese in Human: a review, Int. J. Occup. Environ. Health., 9, 153-163. https://doi.org/10.1179/oeh.2003.9.2.153
  20. Meltzer, H. M., Brantsaeter, A. L., Borch-Iohnsen, B., Ellingsen, D. G., Alexander, J., Thomassen, Y., Stigum, H., Ydersbond, T. A., 2010, Low iron stores are related to higher blood concentrations of manganese, cobalt and cadmium in non- smoking, Norwegian women in the HUNT 2 study, Environ. Res., 110, 497-504. https://doi.org/10.1016/j.envres.2010.03.006
  21. Mergler, D., Baldwin, M., Belanger, S., Larribe, F., Beuter, A., Bowler, R., Panisset, M., Edward, R., de Geoffroy, A., Sassine, M. P., Hudnell, K., 1999, Manganese neurotoxicity, a continuum of dysfunction: results from a community-based study, Neurotoxicology., 20, 327-342.
  22. Moon, D. H., Son, B. C., Kang, D. M., 1999, Manganese Exposure and its Health Hazards of Welders, Korea. J. Occup. Environ. Med., 11(4), 476-491.
  23. National Institute of Environmental Research, 2010, The First Stage ('09-'11) 2nd Year Annual Report on Korea National Environmental Health Survey.
  24. National Institute of Environmental Research, 2011, Annual Report of Air Quality in Korea 2010.
  25. Pizzol, M., Thomsen, M., Anderson, M. S., 2010, Long-term human exposure to lead from different media and intake pathways. Science. of the Environment., 407, 5478-5488.
  26. Roels, H. A., Ghyselen, P. G., Buchet, J. P., Ceulemans, E., Lauwerys, R. R., 1992, Assessment of the permissible exposure level to manganese in workers exposed to manganese dioxide dust, Br. J. Ind. Med., 49, 25-34.
  27. Sarmento, S., Wolterbeek, H. T., Verburg, T. G., Freitas, M.C., 2008, Correlating element atmospheric deposition and cancer mortality in Portugal: data handling and preliminary results, Environmental. Pollution., 151, 341-351. https://doi.org/10.1016/j.envpol.2007.06.039
  28. Shah, M. H., Shaheen, N., Jaffar, M., Khalique, A., Tariq, S. R., Manzoor, S., 2006, Spatial variations in selected metal contents and particle size distribution in an urban and rural atmosphere of Islamabad, Pakistan, J. of Environmental. Management., 78, 128-137. https://doi.org/10.1016/j.jenvman.2005.04.011
  29. Shaheen, N., Shah, M. H., Khalique, A., Jaffar, M., 2005, Metal levels in airborne particulate matter in urban Islamabad, Pakistan, Bulletin. of Environmental. Contamination and Toxicology., 75, 739-746. https://doi.org/10.1007/s00128-005-0813-x
  30. Sjögren, B., Gustavsson, P., Hogstedt, C., 1990, Neuropsychiatric symptoms among welders exposed to neurotoxic metals, Br. J. Ind. Med., 47, 704-707.
  31. Tsalev, D. L., Zaproanov, Z. K., 1983, Atomic absorption spectrometry in occupational and environmental health practice. Vol. I. Analytical aspects and health significance, Florida, CRC press, 153-158.
  32. US-EPA, 1984, Health Assessment Document for Manganese, Final report, Cincinnati, America.
  33. Wappelhorst, O., Khn, J., Oehlmann, J., Korhammer, S., Markert, B., 2000, Deposition and disease: a moss monitoring project as an approach to ascertaining potential connections, Science. of the Total. Environment., 249, 243-256. https://doi.org/10.1016/S0048-9697(99)00521-5
  34. WHO, 1981, Environmental Health Criteria 17: Manganese. World Health Organization. Geneva, Switzerland.

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