Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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Mycoplasma pneumoniae associated stroke in a 3-year-old girl

  • Kim, Gun-Ha (Department of Pediatrics, Korea University College of Medicine) ;
  • Seo, Won Hee (Department of Pediatrics, Korea University College of Medicine) ;
  • Je, Bo-Kyung (Department of Radiology, Korea University College of Medicine) ;
  • Eun, So-Hee (Department of Pediatrics, Korea University College of Medicine)
  • 투고 : 2012.09.14
  • 심사 : 2013.01.15
  • 발행 : 2013.09.15
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초록

Infectious diseases precede a significant proportion of acute ischemic strokes in children. Here, we report a case of acute ischemic stroke in a 3-year-old girl with a Mycoplasma pneumonia-associated respiratory tract infection. She developed an acquired prothrombotic state of protein S deficiency and had increased fibrinogen and fibrinogen degradation product levels and increased titer of antinuclear antibodies. However, these conditions were completely alleviated at the 1-month follow-up examination. Infection with M. pneumoniae may cause a transient prothrombotic state that can potentially cause a thrombus.

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참고문헌

  1. Kirkham FJ. Stroke in childhood. Arch Dis Child 1999;81:85-9. https://doi.org/10.1136/adc.81.1.85
  2. Mackay MT, Wiznitzer M, Benedict SL, Lee KJ, Deveber GA, Ganesan V, et al. Arterial ischemic stroke risk factors: the International Pediatric Stroke Study. Ann Neurol 2011;69:130-40. https://doi.org/10.1002/ana.22224
  3. Ovetchkine P, Brugieres P, Seradj A, Reinert P, Cohen R. An 8-yold boy with acute stroke and radiological signs of cerebral vasculitis after recent Mycoplasma pneumoniae infection. Scand J Infect Dis 2002;34:307-9. https://doi.org/10.1080/00365540110077452
  4. Ryu JS, Kim HJ, Sung IY, Ko TS. Posterior cerebral artery occlusion after Mycoplasma pneumoniae infection associated with genetic defect of MTHFR C677T. J Child Neurol 2009;24:891-4. https://doi.org/10.1177/0883073808331081
  5. Nakahata C, Kittka E, Fujii H, Sakano T, Usui T. A case of cerebral infarction associated with Mycoplasma pneumoniae infection. Hiroshima J Med Sci 1983;32:277-9.
  6. Leonardi S, Pavone P, Rotolo N, La Rosa M. Stroke in two children with Mycoplasma pneumoniae infection: a causal or casual relationship? Pediatr Infect Dis J 2005;24:843-5. https://doi.org/10.1097/01.inf.0000177284.88356.56
  7. Lee CY, Huang YY, Huang FL, Liu FC, Chen PY. Mycoplasma pneumoniae-associated cerebral infarction in a child. J Trop Pediatr 2009;55:272-5. https://doi.org/10.1093/tropej/fmn115
  8. Fu M, Wong KS, Lam WW, Wong GW. Middle cerebral artery occlusion after recent Mycoplasma pneumoniae infection. J Neurol Sci 1998;157:113-5. https://doi.org/10.1016/S0022-510X(98)00074-4
  9. Tanir G, Aydemir C, Yilmaz D, Tuygun N. Internal carotid artery occlusion associated with Mycoplasma pneumoniae infection in a child. Turk J Pediatr 2006;48:166-71.
  10. Dowd AB, Grace R, Rees WD. Cerebral infarction associated with Mycoplasma pneumoniae infection. Lancet 1987;2:567.
  11. Parker P, Puck J, Fernandez F. Cerebral infarction associated with Mycoplasma pneumoniae. Pediatrics 1981;67:373-5.
  12. Visudhiphan P, Chiemchanya S, Sirinavin S. Internal carotid artery occlusion associated with Mycoplasma pneumoniae infection. Pediatr Neurol 1992;8:237-9. https://doi.org/10.1016/0887-8994(92)90078-D
  13. Antachopoulos C, Liakopoulou T, Palamidou F, Papathanassiou D, Youroukos S. Posterior cerebral artery occlusion associated with Mycoplasma pneumoniae infection. J Child Neurol 2002;17:55-7. https://doi.org/10.1177/088307380201700115
  14. Joo CU, Kim JS, Han YM. Mycoplasma pneumoniae induced popliteal artery thrombosis treated with urokinase. Postgrad Med J 2001;77:723-4. https://doi.org/10.1136/pmj.77.913.723
  15. Padovan CS, Pfister HW, Bense S, Fingerle V, Abele-Horn M. Detection of Mycoplasma pneumoniae DNA in cerebrospinal fluid of a patient with M. pneumoniae infection-"associated" stroke. Clin Infect Dis 2001;33:E119-21. https://doi.org/10.1086/323461

피인용 문헌

  1. Mycoplasma pneumoniae Infection : Risk Factor for Childhood Stroke vol.2, pp.None, 2013, https://doi.org/10.1177/2333794x15592764
  2. Individuality, phenotypic differentiation, dormancy and ‘persistence’ in culturable bacterial systems: commonalities shared by environmental, laboratory, and clinical microbiology vol.4, pp.None, 2013, https://doi.org/10.12688/f1000research.6709.2
  3. Central retinal artery occlusion and cerebral infarction associated with Mycoplasma pneumonia infection in children vol.16, pp.1, 2013, https://doi.org/10.1186/s12887-016-0750-3
  4. Evaluation of variation in coagulation among children with Mycoplasma pneumoniae pneumonia: a case–control study vol.45, pp.6, 2017, https://doi.org/10.1177/0300060517709613
  5. Extensive and Progressive Cerebral Infarction after Mycoplasma pneumoniae Infection vol.32, pp.2, 2017, https://doi.org/10.4266/kjccm.2016.00283
  6. Immunotherapy for arterial ischaemic stroke in childhood: a systematic review vol.102, pp.5, 2013, https://doi.org/10.1136/archdischild-2016-311034
  7. A role of infection in the development of hemorrhagic stroke in children vol.118, pp.5, 2013, https://doi.org/10.17116/jnevro20181185231
  8. Low Diagnostic Yield of Routine Cerebrospinal Fluid Analysis in Juvenile Stroke vol.9, pp.None, 2013, https://doi.org/10.3389/fneur.2018.00694
  9. Stroke Associated With Recent Mycoplasma Pneumoniae Infection: A Systematic Review of Clinical Features and Presumed Pathophysiological Mechanisms vol.9, pp.None, 2013, https://doi.org/10.3389/fneur.2018.01109
  10. Mycoplasma pneumoniae infection presenting as stroke and meningoencephalitis with aortic and subclavian aneurysms without pulmonary involvement vol.2018, pp.jan_111, 2018, https://doi.org/10.1136/bcr-2017-221831
  11. Thrombotic Complications of Nose and Toe Associated With Mycoplasma pneumoniae Infection vol.10, pp.10, 2019, https://doi.org/10.14740/jmc3349
  12. Mechanical thrombectomy for a 12-year-old boy with acute ischemic stroke : A case report vol.99, pp.30, 2013, https://doi.org/10.1097/md.0000000000021436
  13. Thrombosis associated with mycoplasma pneumoniae infection (Review) vol.22, pp.3, 2013, https://doi.org/10.3892/etm.2021.10399