Clinical and Experimental Pediatrics

대한소아청소년과학회 (The Korean Pediatric Society)
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Lower fat and better quality diet therapy for children with pharmacoresistant epilepsy

  • Yoon, Jung-Rim (Division of Pediatric Neurology, Department of Pediatrics, Pediatric Epilepsy Clinic, Epilepsy Research Institute, Severance Children's Hospital, Yonsei University College of Medicine) ;
  • Kim, Heung Dong (Division of Pediatric Neurology, Department of Pediatrics, Pediatric Epilepsy Clinic, Epilepsy Research Institute, Severance Children's Hospital, Yonsei University College of Medicine) ;
  • Kang, Hoon-Chul (Division of Pediatric Neurology, Department of Pediatrics, Pediatric Epilepsy Clinic, Epilepsy Research Institute, Severance Children's Hospital, Yonsei University College of Medicine)
  • 투고 : 2013.02.18
  • 심사 : 2013.06.04
  • 발행 : 2013.08.15
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초록

The ketogenic diet (KD) is an established, effective, nonpharmacologic treatment for children with pharmacoresistant epilepsy. Although the KD is the most well-established dietary therapy for epilepsy, it is too restrictive and is associated with serious complications; therefore, alternative lower-fat diets, including a modified Atkins diet and low-glycemic index diet, have been developed. Recent ongoing clinical evidence suggests that other dietary therapies have an efficacy almost comparable to that of the KD. In addition, a diet rich in polyunsaturated fatty acids appears to increase the efficacy of diet therapy and reduce the complications of a high-fat diet. Here, we review the systematic information about lower-fat diets and better-quality dietary therapies and the current clinical status of each of these dietary approaches.

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참고문헌

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피인용 문헌

  1. Ketogenic diet in epilepsy: an updated review vol.26, pp.1, 2013, https://doi.org/10.21307/jepil-2018-004