The Journal of the Korean dental association (대한치과의사협회지)

The Korean Dental Association (대한치과의사협회)
권호 표지

Development of Root Perforation Filling Material using Demineralized Dentin Paste

치아들을 탈회동결건조처리하여 제작한 치근천공부 충전재 개발 I: 예비실험연구

  • Choi, Yong-Hun (Department of Conservative Dentistry, Section of Dentistry, Seoul National University Bundang Hospital) ;
  • Bae, Ji-Hyun (Department of Conservative Dentistry, Section of Dentistry, Seoul National University Bundang Hospital) ;
  • Park, Ji-Hoon (Department of Conservative Dentistry, Section of Dentistry, Seoul National University Bundang Hospital) ;
  • Kim, Young-Kyun (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital) ;
  • Yun, Pil-Young (Department of Oral and Maxillofacial Surgery, Section of Dentistry, Seoul National University Bundang Hospital) ;
  • Hwang, Ji-Yeon (Preclinical Research Center, Biomedical Research Institute, Seoul National University Bundang Hospital) ;
  • Um, In-Woong (Korea Tooth Bank, R&D Institute) ;
  • Lee, Chong-Heon (Department of Oral Pathology, College of Dentistry, Dankook University)
  • 최용훈 (분당서울대학교병원 치과 보존과) ;
  • 배지현 (분당서울대학교병원 치과 보존과) ;
  • 박지훈 (분당서울대학교병원 치과 보존과) ;
  • 김영균 (분당서울대학교병원 구강악안면외과) ;
  • 윤필영 (분당서울대학교병원 구강악안면외과) ;
  • 황지연 (분당서울대학교병원 의생명연구원 전임상실험센터) ;
  • 엄인웅 (한국치아은행 연구소) ;
  • 이종헌 (단국대학교 치과대학 구강병리학교실)
  • Received : 2012.07.30
  • Accepted : 2012.08.27
  • Published : 2012.09.01
Download PDF
⟨ Previous Next ⟩

Abstract

Purpose : This study was performed to evaluate the healing response around the root perforation restorative material. Materials and Methods : Four beagle dogs were used for experimental study. Endodontic treatment was performed at four maxillary premolars and artificial perforation was formed at furcation area of pulp chamber. Canal was filled with gutta percha cone and the perforation was sealed with MTA at group 1. At group 2, canal was filled and the perforation was sealed with dentin paste. Tooth paste was fabricated using extracted human teeth. Histologic examination of furcation area was performed 2, 4, 8 and 12 weeks after experiment. Results : New trabecular bone formation was observed around the MTA and tooth paste. Lamellar bone was observed as time is over. There were no inflammatory reaction in both groups. Conclusion : There is a possibility which endodontic filling material can be developed using extracted teeth.

Keywords

References

  1. Hargreaves KM, Cohen S. Pathways of the pulp 10th ed. 2010.
  2. Torabinejad M, Hong CU, Lee SJ, Monsef M, Pitt Ford TR. Investigation of mineral trioxide aggregate for root-filling in dogs. J Endod 1995;21:603-608. https://doi.org/10.1016/S0099-2399(06)81112-X
  3. Torabinejad M, Pitt Ford TR. Root-end filling materials: a review. Endod Dent Traumatol 1996;12:161-178. https://doi.org/10.1111/j.1600-9657.1996.tb00510.x
  4. Torabinejad M, Pitt Ford TR, McKendry DJ, Abedi HR, Miller A, Kariyawasam SP. Histologic assessment of mineral tri-oxide aggregate as a root-end filling in monkeys. J Endod 1997;23:225-228. https://doi.org/10.1016/S0099-2399(97)80051-9
  5. Wu M, Kontakiotis EG, Wesselink PR. Long-term seal provided by some root-end filling materials. J Endod 1998;24:557-560. https://doi.org/10.1016/S0099-2399(98)80077-0
  6. Shabahang S, Torabinejad M, Boyne PP, Abedi H, McMillan P. A comparative study of root-end induction using os-teogenic protein-1, calcium hydroxide and mineral trioxide aggregate in dogs. J Endod 1999;25:1-5.
  7. Bates CF, Carners DL, Del Rio CE. Longitunal sealing ability of MTA as a root-end filling material. J Endod 1996;22:575-578 https://doi.org/10.1016/S0099-2399(96)80023-9
  8. Keiser K, Johnson C, Tipton DA. Cytotoxicity of MTA using human periodontal ligament fibroblasts. J Endod 2000;26:288-289. https://doi.org/10.1097/00004770-200005000-00010
  9. Economides N, Liolios E, Kolokuris I, Beltes P. Long-term evaluation of the influence of smear layer removal on the sealing ability of different sealers. J Endod. 1999 Feb;25(2):123-5. https://doi.org/10.1016/S0099-2399(99)80010-7
  10. Holland R, de Souza V, Nery MJ, Otoboni Filho JA, Bernab? PF, Dezan J?nior E. Reaction of dogs' teeth to root canal filling with mineral trioxide aggregate or a glass ionomer sealer. J Endod. 1999 Nov;25(11):728-30. https://doi.org/10.1016/S0099-2399(99)80118-6
  11. Nanci A. Ten Cate's Oral Histology, 7thedi. Elsevier Inc. 2008; 202-211.
  12. Min BM. Oral Biochemistry. Daehan Narae Pub Co. Seoul.2007;22-26.
  13. Bhaskar SN. Orban's Oral histology and embryology. 9th edition. Mosby Co. USA. 1980; 47, 107, 180, 252.
  14. Kim YK, Kim SG, Byeon JH, Lee HJ, Um IU, Lim SC, Kim SY. Development of a novel bone grafting material using autogenous teethOral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:496-503. https://doi.org/10.1016/j.tripleo.2009.10.017
  15. Kim YK, Lee JY. The evaluation of postoperative safety of autogenous teeth bone graft. The J Kor Acad Implant Dent 2009;28:29-35.
  16. Weine FS. Endodontic therapy. 6th ed. St. Louis: Mosby; 2004
  17. Sinai IH. Endodontic perforations: their prognosis and treatment. J Am Dent Assoc 1977;95:90-5. https://doi.org/10.14219/jada.archive.1977.0531
  18. Fuss Z, Trope M. Root perforations: classification and treatment choices based on prognostic factors. Endod Dent Traumatol 1996;12:255-64 https://doi.org/10.1111/j.1600-9657.1996.tb00524.x
  19. Moller AJ, Fabricius L, Dahlen G, Ohman A, Heyden G. Influence of periapical tissues of indigenous oral bacterial and necrotic pulp tissues in monkeys. Scand J Dent res. 1981;89:475?84.
  20. Fuss Z, Trope M. Root perforations: Classification and treatment choices based on prognostic factors. Endod Dent Traumatol. 1996;12:255-64. https://doi.org/10.1111/j.1600-9657.1996.tb00524.x
  21. Torabinejad, M. and M. Parirokh (2010). Mineral trioxide aggregate: a comprehensive literature review-part II: leakage and biocompatibility investigations. J Endod 36(2): 190-202. https://doi.org/10.1016/j.joen.2009.09.010
  22. Hardy I, Liewehr FR, Joyce AP, Agee K, Pashley DH. Sealing ability of One-Up Bond and MTA with and without a secondary seal as furcation perforation repairmaterials. J Endod 2004;30:658-61. https://doi.org/10.1097/01.DON.0000121619.33952.9A
  23. Weldon JK Jr, Pashley DH, Loushine RJ, Weller RN, Kimbrough WF. Sealing ability of mineral trioxide aggregate and super-EBA when used as furcation repair materials: a longitudinal study. J Endod 2002;28:467-70. https://doi.org/10.1097/00004770-200206000-00013
  24. Daoudi MF, Saunders WP. In vitro evaluation of furcal perforation repair using mineral trioxide aggregate or resin modified glass ionomer cement with and without the use of the operating microscope. J Endod 2002;28:512-5. https://doi.org/10.1097/00004770-200207000-00006
  25. Lee SJ, Monsef M, Torabinejad M. Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations. J Endod 1993;19:541-4. https://doi.org/10.1016/S0099-2399(06)81282-3
  26. Nakata TT, Bae KS, Baumgartner JC. Perforation repair comparing mineral trioxide aggregate and amalgam using an anaerobic bacterial leakage model. J Endod 1998;24:184-6. https://doi.org/10.1016/S0099-2399(98)80180-5
  27. Ferris DM, Baumgartner JC. Perforation repair comparing two types of mineral trioxide aggregate. J Endod 2004;30:422-4. https://doi.org/10.1097/00004770-200406000-00011
  28. Hashem AAR, Hassanien EE. ProRoot MTA, MTA-Angelus and IRM used to repair large furcation perforations: sealability study. J Endod 2008;34:59-61. https://doi.org/10.1016/j.joen.2007.09.007
  29. Torabinejad M, Hong CU, Lee SJ, Monsef M, Pitt Ford TR. Investigation of mineral trioxide aggregate for root-end filling in dogs. J Endod. 1995;21:603-8. https://doi.org/10.1016/S0099-2399(06)81112-X
  30. Torabinejad M, Pitt Ford TR, McKendry DJ, Abedi HR, Miller DA, Kariyawasen SP. Histologic assessment of MTA as root end filling in monkeys. J Endod. 1997;23:225-8. https://doi.org/10.1016/S0099-2399(97)80051-9
  31. Torabinejad M, Chivian N. Cinical applications of mineral trioxide aggregate. J Endod. 1999;25:197-205. https://doi.org/10.1016/S0099-2399(99)80142-3
  32. Pitt Ford TR, TorabinejadM,McKendry DJ, Hong CU, KariyawasamSP. Use of mineral trioxide aggregate for repair of furcal perforations. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995;79:756-62. https://doi.org/10.1016/S1079-2104(05)80313-0
  33. Al-Daafas A, Al-Nazhan S. Histological evaluation of contaminated furcal perforation in dogs' teeth repaired by MTA with or without internal matrix. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103:e92-9. https://doi.org/10.1016/j.tripleo.2006.09.007
  34. RafterM, BakerM, AlvesM, Daniel J, Remeikis N. Evaluation of healing with use of an internal matrix to repair furcation perforations. Int Endod J 2002;35:775-83. https://doi.org/10.1046/j.1365-2591.2002.00566.x
  35. Tziafas D, Kolokuris I. Inductive influences of demineralized dentin and bone matrix on pulp cells: an approach of secondary dentinogenesis. J Dent Res 1990;69:65-81.
  36. Nakashima M. Induction of dentin formation on canine amputated pulp by recombinant human bone morphogenetic proteins (BMP)-2 and -4. J Dent Res 1994;73:1515-22. https://doi.org/10.1177/00220345940730090601
  37. Jiang Y, Sun M, Wu D. Clinical studies on apexification with demineralized dentin matrix. Hua Xi Kou Qiang Yi Xue Za Zhi 2003;21:460-2.
  38. Kim YK, Kim SG, Oh JS, Jin SC, Son JS, Kim SY, Lim SY. Analysis of the inorganic component of autogenous tooth bone graft material. J Nanosci Nanotechnol. 2011;11:7442-5. https://doi.org/10.1166/jnn.2011.4857
  39. Kim YK, Choi YH. Tooth autotransplantation with autogenous tooth-bone graft: A case report. J Korean Dent Sci 2011;4(2):79-84. https://doi.org/10.5856/JKDS.2011.4.2.79
  40. Kim JY, Kim KW, Um IW, Kim YK, Lee JK. Bone healing capacity of demineralized dentin matrix materials in a mini-pig cranium defect. J Korean Dent Sci 2012;5(1):21-8. https://doi.org/10.5856/JKDS.2012.5.1.21
  41. Kim YK, Lee HJ, Kim KW, Kim SGm Um IW. Guided bone regeneration using autogenous teeth: case reports. J Korean Assoc Oral Maxillofac Surg 2011;37:142-147. https://doi.org/10.5125/jkaoms.2011.37.2.142
  42. Kim YK, Kim SG. Kim KW, Um IW. Extraction socket preservation and reconstruction using autogenous tooth bone graft. J Korean Assoc Maxillofac Plast Reconstr Surg 2011;33:264-269.