Korean Journal of Metals and Materials (대한금속재료학회지)

The Korean Institute of Metals and Materials (대한금속재료학회)
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Bio-applicable Ti-based Composites with Reduced Image Distortion Under High Magnetic Field

높은 자장하에서 자기공명 영상 왜곡이 완화된 생체용 Ti 복합재료

  • Kim, Sung-Chul (Department of Materials Science and Engineering, Korea University) ;
  • Kim, Yu-Chan (Biomedical Research Institute, Korea Institute of Science and Technology) ;
  • Seok, Hyun-Kwang (Biomedical Research Institute, Korea Institute of Science and Technology) ;
  • Yang, Seok-Jo (College of Engineering, Chungnam National University) ;
  • Shon, In-Jin (Division of Advanced Materials Engineering, Chonbuk National University) ;
  • Lee, Kang-Sik (Department of Orthopedic Surgery, ASAN Medical Center) ;
  • Lee, Jae-Chul (Department of Materials Science and Engineering, Korea University)
  • 김성철 (고려대학교 신소재공학부) ;
  • 김유찬 (한국과학기술연구원 생체재료연구단) ;
  • 석현광 (한국과학기술연구원 생체재료연구단) ;
  • 양석조 (충남대학교 메카트로닉스공학과) ;
  • 손인진 (전북대학교 신소재공학부) ;
  • 이강식 (현대아산병원 정형외과) ;
  • 이재철 (고려대학교 신소재공학부)
  • Received : 2011.12.01
  • Published : 2012.05.25
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Abstract

When viewed using a magnetic resonance imaging (MRI) system, invasive materials inside the human body, in many cases, severely distort the MR image of human tissues. The degree of the MR image distortion increases in proportion not only to the difference in the susceptibility between the invasive material and the human tissue, but also to the intensity of the magnetic field induced by the MRI system. In this study, by blending paramagnetic Ti particles with diamagnetic graphite, we synthesized $Ti_{100-x}C_x$ composites that can reduce the artifact in the MR image under the high-strength magnetic field. Of the developed composites, $Ti_{70}C_{30}$ showed the magnetic susceptibility of ${\chi}=67.6{\times}10^{-6}$, which corresponds to 30% of those of commercially available Ti alloys, the lowest reported in the literature. The level of the MR image distortion in the vicinity of the $Ti_{70}C_{30}$ composite insert was nearly negligible even under the high magnetic field of 4.7 T. In this paper, we reported on a methodology of designing new structural materials for bio-applications, their synthesis, experimental confirmation and measurement of MR images.

Keywords

Acknowledgement

Supported by : 한국과학기술연구원

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