The Korea Journal of Herbology (대한본초학회지)

The Korea Association of Herbology (대한본초학회)
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Cosmeceutical Activities of Doinseunguitang and Its Composition

도인승기탕 및 그 구성약재의 화장품약리활성

  • Lee, Jin-Young (Department of Herbal Cosmetic Science, Hoseo University) ;
  • Lee, Soo-Yeon (Department of Herbal Cosmetic Science, Hoseo University) ;
  • Jun, Hye-Ji (Department of Herbal Cosmetic Science, Hoseo University) ;
  • Yoon, Ji-Young (Department of Herbal Cosmetic Science, Hoseo University) ;
  • Hwang, Hyun-Uk (Department of Herbal Cosmetic Science, Hoseo University) ;
  • Park, Joo-Hoon (Department of Herbal Cosmetic Science, Hoseo University) ;
  • An, Bong-Jeun (Department of Cosmeceutical Science, Daegu Haany University) ;
  • Son, Jun-Ho (Korea Promotion Institute for Traditional Medicine Industry) ;
  • Hwang, Ju-Young (Korea Promotion Institute for Traditional Medicine Industry)
  • 이진영 (호서대학교 한방화장품과학과) ;
  • 이수연 (호서대학교 한방화장품과학과) ;
  • 전혜지 (호서대학교 한방화장품과학과) ;
  • 윤지영 (호서대학교 한방화장품과학과) ;
  • 황현욱 (호서대학교 한방화장품과학과) ;
  • 박주훈 (호서대학교 한방화장품과학과) ;
  • 안봉전 (대구한의대학교 화장품약리학과) ;
  • 손준호 (한국한방산업진흥원) ;
  • 황주영 (한국한방산업진흥원)
  • Received : 2012.07.24
  • Accepted : 2012.09.06
  • Published : 2012.09.30
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Abstract

Objectives : Cosmeceutical activities such as anti-oxidative and anti-aging effects of the Doinseunguitang and its composition, a traditional prescription, were evaluated. Methods : We performed MTT assay, melanin synthesis inhibition assay, DPPH free radical scavenging assay, SOD-like activity, xanthine oxidase inhibition assay, astringent activity assay, tyrosinase inhibition assay, elastase and collagenase inhibition assay. Results : The results were obtained as follows : DPPH free radical scavenging of water extract Doinseunguitang (DISG) and ethanol extract DISG was 60% and 50% at 1,000 ppm. Xanthine oxidase inhibition effect of ethanol extract showed more than 80% at 500 ppm. Tyrosinase inhibition and inhibition melanin synthesis activities were measured in 40% and 50% at 1,000 ppm and 100 ppm. Elastase and collagenase inhibition rate of ethanol extracts DISG 40% and 80% at 1,000 ppm. It was concluded that compositive ingredients (Persicae Seman, Glycyrrhizae Radix, Cinnamomi Ramulus, Rhei Rhizoma) influenced the most results. Conclusions : The results indicated that, ethanol extract which is superior in its anti-oxidative and anti-aging effects is useful to be applied in herbal cosmetic industry.

Keywords

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