References
- Yu, B.P. Aging and oxidative stress: modulation by dietary restriction. Free Radic Biol Med. 21: 651-668, 1996. https://doi.org/10.1016/0891-5849(96)00162-1
-
Helmer, K.S., Chang, L., Cui, Y., and Mercer, D.W. Induction of NF-
${\kappa}B$ ,$I{\kappa}B-{\alpha}$ , and iNOS in rat gastric mucosa during endotoxemia. J Surg Res. 104(1):46-52, 2002. https://doi.org/10.1006/jsre.2002.6404 - Carr, A.C. Oxidation of LDL by myeloperoxidase and reactive nitrogen species: reaction pathways and antioxidant protection. Arterioscler Thromb Vasc Biol. 20: 1716-1723, 2000. https://doi.org/10.1161/01.ATV.20.7.1716
- Haenen, G.R., Paquay, J.B., Korthouwer, R.E., and Bast, A. Peroxynitrite scavenging by flavonoids. Biochem Biophy Res Commu. 236(3):591-593, 1997. https://doi.org/10.1006/bbrc.1997.7016
-
Kim, H.J., Kim, K.W., Yu, B.P., and Chung, H.Y. The effct of age on cyclooxygenase-2 gene expression: NF-
${\kappa}B$ activation and$I{\kappa}B{\alpha}$ degradation. Free Radic Biol Med. 28(5):683-692, 2000. https://doi.org/10.1016/S0891-5849(99)00274-9 -
Baeuerle, P.A., and Henkei, T. Function and activation of NF-
${\kappa}B$ in the immune system. Annu Rev Immunol. 12: 141-179, 1994. https://doi.org/10.1146/annurev.iy.12.040194.001041 - Nathan, C.F., and Hibbs, J.B. Roles of nitric oxide synthesis in macrophage antimicrobial activity. Curr Opin Immunol. 1: 65-70, 1991.
- Kawamori, T., Rao, C.V., Seibert, K., and Reddy, B.S. Chemopreventive activity of elecoxib, a pecific cyclooxygenase-2 Inhibitor, against colon carcinogenesis. Cancer Res. 58: 409-412, 1998.
-
Lawrence, T., Gilroy, D.W., Colville-Nash, P.R., and Willoughby, D.A. Possible new role for NF-
${\kappa}B$ in the resolution of inflammation. Nat Med. 7(12):1291-1297, 2001. https://doi.org/10.1038/nm1201-1291 - Korhonen, P., Helenius, M., and Salminen, A. Age-related chages in the reguration of transcription factor NF-kappa B in rat brain. Neurosci Lett. 225: 61-64, 1997. https://doi.org/10.1016/S0304-3940(97)00190-0
- 全國韓醫科大學共同敎材編纂委員會編著. 本草學. 서울, 永林社, pp 462-463, 2005.
- 정운석, 이주일, 서운교. 백일해 유발균 Bordetella pertussis 에 대한 虎杖根의 생육억제 효과. 대한한방내과학회지 26(3):543-550, 2005.
- 이태규, 김종화, 소준노. 虎杖根으로부터 분리된 emodin의 혈관신생 억제 활성. 한국농화학회지 46(1):50-54, 2003.
- 김동조, 김호현, 고흥. 虎杖根물추출물의 내피세포 의존성 혈관이완효과. 동의생리병리학회지 22(1):131-136, 2008.
- 최변탁, 김연희, 이동녕, 김형준. 虎杖根이 子宮頸部癌細胞의 成長抑制및 細胞枯死에 미치는 영향. 대한한방부인과학회지 19(1):1-13, 2006.
- 김지연, 양기숙. 虎杖根의 사염화탄소로 유도된 지질과산화 저해활성. 약학회지 43(5):572-576, 1999.
- 이인선, 임효권, 이승욱. 虎杖根에 의한 Helicobacter pylori의 생육 저해. 한국식품과학회지 35(6):1182-1187, 2003.
- Tada, H., Shiho, O., Kuroshima, K., Koyama, M., and Tsukamoto, K. An improved colorimetric assay for interleukin 2. J Immunol Methods. 93(2):157-165, 1986. https://doi.org/10.1016/0022-1759(86)90183-3
- Cathcart, R., Schwiers, E., and Ames, B.N. Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein fluorescent assay. Anal Biochem. 134: 111-116, 1983. https://doi.org/10.1016/0003-2697(83)90270-1
- Nagata, N., Momose, K., and Ishida, Y. Inhibitory effects of catecholamines and anti-oxidants on the fluorescence reaction of 4,5-diaminofluorescein, DAF-2, a novel indicator of nitric oxide. J Biochem Tokyo. 125: 658-661, 1999. https://doi.org/10.1093/oxfordjournals.jbchem.a022333
- Kooy, N.W., Royall, J.A., Ischiropoulos, H., and Beckman, J.S. Peroxynitrite-mediated oxidated oxidation of dihydrorhodamine 123. Free Radic Res Commun. 16: 149-1456, 1994.
- Lowry, O.H., Rosebrough, N.J., Farr, A.L., and Randall, R.J. Protein measurement with the Folin phenol reagent. J Biol Chem. 193(1):265-275, 1951.
- 陶弘景. 名醫別錄. 북경, 人民衛生出版社, pp 228-229, 1986.
- 許浚. 東醫寶鑑. 서울, 법인문화사, p 1962, 1999.
- Qian, G., Leung, S., Lu, G., and Leung, K. Differentiation of Rhizoma Et Radix Poligoni Cuspidati from Closely Related Herbs by HPLC Fingerprinting. Chem Pharm Bull. 54: 1179-1186, 2006. https://doi.org/10.1248/cpb.54.1179
- Sato, M., Maulik, G., Bagchi, D., and Das, D.K. Myocardial protection by protykin, a novel extract of trans-resveratrol and emodin. Free Radic Res. 32: 135-144, 2000. https://doi.org/10.1080/10715760000300141
- Jayasuriya, H., Koonchanok, N.M., Geahlen, R.L., MacLaughlin, J.L., and Chang, C.J. Emodin, a protein kinase inhibitor from Polygonum cuspidatum. J. Nat. Prod. pp 55, 696-698, 1992. https://doi.org/10.1021/np50083a026
-
Kumar, A., Dhawan, S., and Aggarwal, B.B. Emodin (3-methyl-1,6,8-trihydroxyanthraquinone) inhibits TNF-induced NF-
${\kappa}B$ activation, IkB degradation, and expression of cell surface adhesion proteins in human vascular endothelial cells. Oncogene pp 17, 913-918, 1998. https://doi.org/10.1038/sj.onc.1201998 - 최병진. 한약의 약리. 서울, 고려의학, pp 117-118, 339, 2000.
- Mates, J.M., Perez-Gomez, C., and Nunez de Castro I. Antioxidant enzymes and human disease. Clin. Biochem. 32(8):595-603, 1999. https://doi.org/10.1016/S0009-9120(99)00075-2
- Shingu, M., Oribe, M., Todoroki, T., Tatsukawa, K., Tomo-Oka, K., Yasuda, M., and Nobunaga, M. Serum factors from patients with systemic lupus erythematosus enhancing superoxide generation by normal neutrophils. J. Invest. Dermatol. 81(3):212-215, 1983. https://doi.org/10.1111/1523-1747.ep12517989
- Pannala, A.S., Rice-Evans, C.A., Halliwell, B., and Singh, S. Inhibition of peroxynitrite- mediated tyrosine nitration by catechin polyphenols. Biochem Biophy Res Commu. 232: 164-170, 1997. https://doi.org/10.1006/bbrc.1997.6254
- Shimokawa, H., Zanchetti, A., and Mancia, G. Handbook of Hypertension. Elvsevier Science. Amsterdam. pp 1007-1068, 1997.
- Chung, H.Y., Kim, H.j., and Kim, J.W. The inflammation hypothesis of aging: Molecular modulation by calorie restriction. Ann N Y Acad Sci. 928: 327-335, 2001.
- Crow, J.P., Beckman, J.S., and McCord, J.M. Sensitivity of the essential zinc-thiolate moiety of yeast alcohol dehydrogenase to hypochlorite and peroxynitrite. Biochemistry. 34(11):3533-3552, 1995.
- 정해영, 성도유, 김애라, 최혜리, 김현진, 최재수. ONOO-의 생성, 독성, 제거 및 노화와 관련성. 한국노화학회지 10(1):46-59, 2000.
- Halushka, P.V., Mais, D.E., Mayeux, P.R., and Morinelli, T.A. Thromboxane, prostaglandin and leukotriene receptors. Annu Rev Pharmacol Toxicol. 29: 213-239, 1989. https://doi.org/10.1146/annurev.pa.29.040189.001241
- Masferrer, J., Zweofel, B.S., Manning, P.T., Hauser, S.D., Leahy, K.M., Smith, W.G., Isacson, P.C., and Seibert, K. Selective inhibition of inducible cyclooxygenase 2 in vivo is anti-inflammatory and nouulcerogenic. Proc. Natl. Acad. U.S.A. 91: 3228-3232, 1994. https://doi.org/10.1073/pnas.91.8.3228
- Seibert, K., Zhang, Y., Leahy, K., Hauser, S., Masferrer, J., Perkins, W., Lee, L., and Ksakson, P. Pharmacoogical and biochemical demonstration and pain. Proc. Natl. Acad. Sci. U.S.A. 91: 12013-12017, 1994. https://doi.org/10.1073/pnas.91.25.12013
- Groszmann, R.J. Hyperdynamic state in chronic liver disease. J Hepatol. 224(1):61-64, 1993.
- Chung, H.Y., Kim, H.J., Kim, K.W., Choi, J.S., and Yu, B.P. Molecular inflammation hypothesis of aging based on the anti-aging mechanism of calorie restriction. Microsc Res Tech. 59(4):264-272, 2002. https://doi.org/10.1002/jemt.10203
- 김선영 외 14명 역. 면역생물학 6판. 서울, 라이프사이언스, p 78, 237, 2005.
- Alagappan, V.K., McKay, S., Widyastuti, A., Garrelds, I.M., Bogers, A.J., and Hoogsteden, H.C. Proinflammatory cytokines upregulate mRNA expression and secretion of vascular endothelial growth factor in cultured human airway smooth muscle cells. Cell Biochem Biophys. 43(1):119-129, 2005. https://doi.org/10.1385/CBB:43:1:119
- Pannala, A.S., Rice-Evans, C.A., Halliwell, B., and Sin, S. Inhibition of peroxynitrite-mediated tyrosine nitration by catechin polyphenoles. Biochem Biophy Res Commu. 232: 164-170, 1997. https://doi.org/10.1006/bbrc.1997.6254