Asian Pacific Journal of Cancer Prevention

Asian Pacific Journal of Cancer Prevention (아시아태평양암예방학회)
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A Multi-center Survey of HPV Knowledge and Attitudes Toward HPV Vaccination among Women, Government Officials, and Medical Personnel in China

  • Zhao, Fang-Hui (Department of Epidemiology, Cancer Institute of Chinese Academy of Medical Sciences, Peking Union Medical College) ;
  • Tiggelaar, Sarah M. (Department of Epidemiology, Cancer Institute of Chinese Academy of Medical Sciences, Peking Union Medical College) ;
  • Hu, Shang-Ying (Department of Epidemiology, Cancer Institute of Chinese Academy of Medical Sciences, Peking Union Medical College) ;
  • Zhao, Na (Department of Disciplines and Science Research Management, First Affiliated Hospital of Dalian Medical University) ;
  • Hong, Ying (Department of Gynaecology and Obstetrics, the Affiliated Drum Tower Hospital of Nanjing University Medical School) ;
  • Niyazi, Mayinuer (Department of Gynaecology and Obstetrics, People's Hospital of Xinjiang Uygur Autonomous Region) ;
  • Gao, Xiao-Hong (Department of Epidemiology, DaLian Medical University) ;
  • Ju, Li-Rong (Department of Women and Children's health, Public Health and Family Medicine Institute, Capital Medical University) ;
  • Zhang, Li-Qin (Department of gynaecology and obstetrics, TianJin Medical University General Hospital) ;
  • Feng, Xiang-Xian (Department of Epidemiology, Shanxi Province Chang Zhi Medical University) ;
  • Duan, Xian-Zhi (Department of Gynaecology and Obstetrics, Beijing Tongren Hospital) ;
  • Song, Xiu-Ling (Feicheng People's Hospital in Shandong Province) ;
  • Wang, Jing (Department of gynaecology, Cancer Hospital of Hunan Province) ;
  • Yang, Yun (Medical College of Yichun University) ;
  • Li, Chang-Qin (Xinmi Maternal and Child Care Hospital) ;
  • Liu, Jia-Hua (Department of Gynaecology and Obstetrics, People's Hospital of Fujian Province) ;
  • Liu, Ji-Hong (Department of Gynaecology, Affiliated Cancer Hospital of Sun Yat-sen University) ;
  • Lu, Yu-Bo (Department of Gynaecology, Cancer Hospital of Yunnan Province) ;
  • Li, Li (Department of Gynaecology and Obstetrics, Daping Hospital of the Third Military Medical University) ;
  • Zhou, Qi (Department of Gynaecology, Cancer Hospital of Chongqing) ;
  • Liu, Jin-Feng (Department of gynaecology and obstetrics, Gansu Provincial Maternal and Child Care Hospital) ;
  • Xu, Li-Na (Department of Health Education, Haidian District Center for Disease Control and Prevention) ;
  • Qiao, You-Lin (Department of Epidemiology, Cancer Institute of Chinese Academy of Medical Sciences, Peking Union Medical College)
  • Published : 2012.05.30
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Abstract

Objectives: To assess knowledge of HPV and attitudes towards HPV vaccination among the general female population, government officials, and healthcare providers in China to assist the development of an effective national HPV vaccination program. Methods: A cross-sectional epidemiologic survey was conducted across 21 urban and rural sites in China using a short questionnaire. 763 government officials, 760 healthcare providers, and 11,681 women aged 15-59 years were included in the final analysis. Data were analyzed using standard descriptive statistics and logistic regression. Results: Knowledge of HPV among the general female population was low; only 24% had heard of HPV. Less than 20% of healthcare providers recognized sexually na$\ddot{i}$ve women as the most appropriate population for HPV vaccination. There was high acceptance of the HPV vaccine for all categories of respondents. Only 6% of women were willing to pay more than US $300 for the vaccine. Conclusions: Aggressive education is necessary to increase knowledge of HPV and its vaccine. Further proof of vaccine safety and efficacy and government subsidies combined with increased awareness could facilitate development and implementation of HPV vaccination in China.

Keywords

References

  1. Brabin L, Roberts SA, Farzaneh F, Kitchener HC (2006). Future acceptance of adolescent human papillomavirus vaccination: A survey of parental attitudes. Vaccine, 24, 3087-94. https://doi.org/10.1016/j.vaccine.2006.01.048
  2. Brewer NT, Fazekas KI (2007). Predictors of HPV vaccine acceptability: A theory-informed, systematic review. Prev Med, 45, 107-14. https://doi.org/10.1016/j.ypmed.2007.05.013
  3. Chen W, Zhang X, Molijn A, et al (2009). Human papillomavirus type-distribution in cervical cancer in China : the importance of HPV 16 and 18. Cancer Causes Control, 20, 1705-13. https://doi.org/10.1007/s10552-009-9422-z
  4. Dempsey AF, Davis MM (2006). Overcoming barriers to adherence to HPV vaccination recommendations. The Am J Manag Care, 12 (17 Suppl), S484-91.
  5. Ferlay J, Shin HR, Bray F, et al (2010). Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int J Cancer, 127, 2893-917. https://doi.org/10.1002/ijc.25516
  6. Hopkins TG, Wood NJ, West RM, Darling JC (2009). UK health professionalsʼ attitudes and knowledge regarding Human Papillomavirus (HPV) vaccination: a West Yorkshire Study. J Paediatr Child Health, 45, 652-5. https://doi.org/10.1111/j.1440-1754.2009.01589.x
  7. Koutsky LA, Ault KA, Wheeler CM, et al (2002). A controlled trial of a human papillomavirus type 16 vaccine. NEJM, 347, 1645-51. https://doi.org/10.1056/NEJMoa020586
  8. Kwan TTC, Chan KKL, Yip AMW, et al (2008). Barriers and facilitators to human papillomavirus vaccination among Chinese adolescent girls in Hong Kong : a qualitative - quantitative study. Sex Transm Infect, 84, 227-32. https://doi.org/10.1136/sti.2007.029363
  9. Kwan TTC, Chan KKL, Yip AMW, et al (2009). Acceptability of human papillomavirus vaccination among Chinese women : concerns and implications. BJOG, 116, 501-10. https://doi.org/10.1111/j.1471-0528.2008.01988.x
  10. Lee PWH, Kwan TTC, Fai K, et al (2007). Beliefs about cervical cancer and human papillomavirus (HPV) and acceptability of HPV vaccination among Chinese women in Hong Kong. Prev Med, 45, 130-4. https://doi.org/10.1016/j.ypmed.2007.07.013
  11. Li J, Li LK, Ma JF, et al (2009). Knowledge and attitudes about human papillomavirus (HPV) and HPV vaccines among women living in metropolitan and rural regions of China. Vaccine, 27, 1210-5. https://doi.org/10.1016/j.vaccine.2008.12.020
  12. Ministry of Health (2007). Ministry of Health (MOH) Chinese Health Statistics Yearbook (p. 337). Beijing, China: Peking Union Medical Press.
  13. Munoz N, Bosch FX, Sanjose S de, et al (2003). Epidemiologic classification of human papillomavirus types associated with cervical cancer. NEJM, 348, 518-27. https://doi.org/10.1056/NEJMoa021641
  14. Panatto D, Amicizia D, Lugarini J, et al (2009). Sexual behaviour in Ligurian (Northern Italy) adolescents and young people: suggestions for HPV vaccination policies. Vaccine, 27 (Suppl 1), A6-10. https://doi.org/10.1016/j.vaccine.2008.10.057
  15. Rong S, Chen W, Wu L, et al (2002). [Analysis of risk factors for cervical cancer in Xiangyuan County, Shanxi Province]. Zhonghua Yu Fang Yi Xue Za Zhi, 36, 41-3.
  16. Shi JF, Qiao YL, Smith JS, et al (2008). Epidemiology and prevention of human papillomavirus and cervical cancer in China and Mongolia. Vaccine, 26 (Suppl 1), M53-9. https://doi.org/10.1016/j.vaccine.2008.05.009
  17. Villa L, Costa R, Petta C, et al (2005). Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: a randomised double-blind placebo-controlled multicentre phase II efficacy trial. Lancet Oncol, 6, 271-8. https://doi.org/10.1016/S1470-2045(05)70101-7
  18. Walboomers JMM, Jacobs MV, Manos MM, et al (1999). Human papillomavirus is a necessary cause of invasive cervical cancer worldwide. J Pathol, 189, 12-9. https://doi.org/10.1002/(SICI)1096-9896(199909)189:1<12::AID-PATH431>3.0.CO;2-F
  19. Woodhall SC, Lehtinen M, Verho T, et al (2007). Anticipated acceptance of HPV vaccination at the baseline of implementation: a survey of parental and adolescent knowledge and attitudes in Finland. JAH, 40, 466-9.
  20. Yang L, Parkin DM, Li L, Chen Y (2003). Time trends in cancer mortality in China: 1987-1999. Int J Cancer, 106, 771-83. https://doi.org/10.1002/ijc.11300
  21. Zhang YZ, Ma JF, Zhao FH, et al (2010). Three-year follow-up results of visual inspection with acetic acid/Lugol's iodine (VIA/VILI) used as an alternative screening method for cervical cancer in rural areas. Chin J Cancer, 29, 4-8 (in Chinese). https://doi.org/10.5732/cjc.009.10687
  22. Zhao FH, Hu SY, Zhang SW, Chen WQ, Qiao YL (2010). Cervical cancer mortality in 2004 - 2005 and changes during last 30 years in China. Chin J Prev Med, 44, 408-12.
  23. Zhao FH, Tiggelaar S, Hu SY, et al (2012). A multi-center survey of age of sexual debut and sexual behavior in Chinese women: suggestions for optimal age of human papillomavirus vaccination in China. Cancer Epidemiol, 36, 384-90. https://doi.org/10.1016/j.canep.2012.01.009

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