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The Korean Society for Biotechnology and Bioengineering (한국생물공학회)
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Enhancement of the Stability and Solubility of Prodigiosin Using β-Cyclodextrin in Seawater

β-Cyclodextrin을 이용한 해수에서의 Prodigiosin의 안정성과 용해도 향상

  • Park, Hee-Yong (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI) ;
  • Kim, Tai-Kyoung (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI) ;
  • Han, Se-Jong (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI) ;
  • Yim, Joung-Han (Division of Polar Life Sciences, Korea Polar Research Institute, KORDI)
  • 박희용 (한국해양연구원 부설 극지연구소 극지생명과학연구부) ;
  • 김태경 (한국해양연구원 부설 극지연구소 극지생명과학연구부) ;
  • 한세종 (한국해양연구원 부설 극지연구소 극지생명과학연구부) ;
  • 임정한 (한국해양연구원 부설 극지연구소 극지생명과학연구부)
  • Received : 2012.02.22
  • Accepted : 2012.04.20
  • Published : 2012.04.30
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Abstract

This research was to examine the effects of various cyclodextrins on the solubility and stability of prodigiosin in seawater. Among them, ${\beta}$-cyclodextrin was found to have the best efficiency and formation of the inclusion complex was saturated when prodigiosin and ${\beta}$-cyclodextrin were mixed in a ratio of 1:8 and shaken at $25^{\circ}C$ and pH 8.0 for 6 h. The maximum algicidal activity against Chattonella antiqua using the inclusion complex stored at $4^{\circ}C$ for 5 weeks of culture was obtained, $52.28{\pm}3.41%$, which was about 5.0 fold higher than that of control. Our results suggest that inclusion complexes of prodigiosin and ${\beta}$-cyclodextrin could serve as effective algicidal agents.

Keywords

References

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