Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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Prevalence and Risk Factors for Mycobacterium tuberculosis Infection among Contacts of Pulmonary Tuberculosis Patients

폐결핵환자 접촉자에서 결핵감염의 빈도와 결핵감염의 위험인자

  • Park, Jae-Seuk (Department of Internal Medicine, Dankook University College of Medicine)
  • 박재석 (단국대학교 의과대학 내과학교실)
  • Received : 2011.10.15
  • Accepted : 2011.12.20
  • Published : 2012.02.29
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Abstract

Background: Detection and treatment of tuberculosis (TB) infection with contact investigation is a key component of TB control program. I evaluated the prevalence and risk factors for TB infection among contacts of recently diagnosed pulmonary TB patients in a tertiary hospital in Korea. Methods: 206 contacts of 90 adult pulmonary TB patients underwent tuberculin skin tests (TST) and chest radiography. The TST results were considered positive with an induration of 10 mm or more, suggesting TB infection. A standardized questionnaire was used to assess risk factors associated with TB infection. Results: TST was positive in 97 of 206 contacts of TB patients (47.1%) and positive rate of TST increased with age. The risk of TB infection was significantly associated with close contact with TB patients (sleeping in the same room) (odd ratio [OR], 4.94; 95% confidence interval [CI], 1.43~17.00). Conclusion: TB infection rate was higher in the elderly, and the risk of TB infection was significantly increased with close contact of TB patients.

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