Tuberculosis and Respiratory Diseases

The Korean Academy of Tuberculosis and Respiratory Diseases (대한결핵및호흡기학회)
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A Case of Primary Lung Cancer Producing Alpha-fetoprotein

알파 태아단백을 분비하는 원발성 폐암 1예

  • Yu, Ji-Hyun (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Ahn, Joong-Hyun (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Chung, Han-Hee (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Kim, Young-Wook (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Yu, Jin-Sok (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine) ;
  • Kim, Ju-Sang (Division of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, The Catholic University of Korea College of Medicine)
  • 유지현 (가톨릭대학교 의과대학 내과학교실 인천성모병원 호흡기내과) ;
  • 안중현 (가톨릭대학교 의과대학 내과학교실 인천성모병원 호흡기내과) ;
  • 정한희 (가톨릭대학교 의과대학 내과학교실 인천성모병원 호흡기내과) ;
  • 김영욱 (가톨릭대학교 의과대학 내과학교실 인천성모병원 호흡기내과) ;
  • 유진석 (가톨릭대학교 의과대학 내과학교실 인천성모병원 호흡기내과) ;
  • 김주상 (가톨릭대학교 의과대학 내과학교실 인천성모병원 호흡기내과)
  • Received : 2011.08.30
  • Accepted : 2011.09.02
  • Published : 2012.01.30
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Abstract

We observed a very rare case of primary lung cancer producing alpha-fetoprotein (AFP). A 70-year-old male with a history of smoking 50 packs per year was diagnosed with large cell carcinoma of the lung. The clinical stage was T2bN3M0 (IIIB), and serum AFP was 23,247 ng/mL. There was no evidence of metastasis to the liver, scrotum or other organs. While undergoing chemotherapy for 1 year, as the cancer progressed the AFP value steadily increased. The patient died of respiratory failure due to pneumonia 12 months after being diagnosed with lung cancer.

Keywords

References

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