Journal of Environmental Health Sciences (한국환경보건학회지)

Korean Society of Environmental Health (한국환경보건학회)
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House Dust Mites and Associated Environmental Factors in Homes of Atopic Children: a Case-Control Study

아토피 아동 가정내 집먼지 진드기 농도와 환경요인: 환자 대조군 연구

  • Kim, Sung-Ho (Department of Environmental Health, Graduate School of Public Health, Seoul National University) ;
  • Park, Dong-Jin (Department of Environmental Health, Graduate School of Public Health, Seoul National University) ;
  • Byun, Hyae-Jeong (Department of Environmental Health, Graduate School of Public Health, Seoul National University) ;
  • Lee, Hyun-Soo (Environmental Health Center, College of Medicine, University of Ulsan) ;
  • Oh, In-Bo (Environmental Health Center, College of Medicine, University of Ulsan) ;
  • Sim, Chang-Sun (Department of Occupational and Environmental Medicine, College of Medicine, University of Ulsan) ;
  • Kim, Yang-Ho (Department of Occupational and Environmental Medicine, College of Medicine, University of Ulsan) ;
  • Yoon, Chung-Sik (Department of Environmental Health, Graduate School of Public Health, Seoul National University)
  • 김성호 (서울대학교 보건대학원 환경보건학과) ;
  • 박동진 (서울대학교 보건대학원 환경보건학과) ;
  • 변혜정 (서울대학교 보건대학원 환경보건학과) ;
  • 이현수 (울산대학교 의과대학 환경보건센터) ;
  • 오인보 (울산대학교 의과대학 환경보건센터) ;
  • 심창선 (울산대학교 의과대학 산업환경의학교실) ;
  • 김양호 (울산대학교 의과대학 산업환경의학교실) ;
  • 윤충식 (서울대학교 보건대학원 환경보건학과)
  • Received : 2012.03.12
  • Accepted : 2012.06.27
  • Published : 2012.06.29
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Abstract

Objectives: The purpose of this study was to determine house dust mite concentrations in living rooms and bedding materials in atopic case-control groups. Methods: Fifty four homes with children suffering atopic diseases as cases and fifty one homes without atopic diseases as controls were selected after diagnosis at three elementary schools in Ulsan City. Dust samples were collected from the living rooms and bedding materials in each home during summer and winter with a vacuum cleaner and analyzed for house dust mites using enzyme-linked immunosorbent assay (ELISA). Environmental factors and family history were surveyed during sampling. Results: Both species of house dust mite Dermatophagoides farina (Der f 1) and Dermatophagoides pteronyssinus (Der p 1) were found in all homes. Derf1 concentrations were much higher than Der P1 concentrations, both in atopic homes (1518.9 vs. 27.0 ng/g. dust, respectively) and non-atopic homes (810.8 vs. 44.3 ng/g. dust, respectively). Der f 1 concentrations were significantly higher in the atopic group than in the non-atopic group (atopic: 1518.9 ng/g.dust, non-atopic: 810.8 ng/g.dust, p = 0.035). However, total house dust mite Der p 1 concentrations were significantly higher in the non-atopic group than in the atopic group (atopic: 27.0 ng/g.dust, non-atopic: 44.3 ng/g.dust, p = 0.035). Multiple regression implied that mothers with family history of atopic diseases (OR = 4.79, 95% CI = 1.81-12.69), Der f 1 concentrations (OR = 1.74, 95% CI = 1.07-2.81), and air freshener use (OR = 4.60, 95% CI = 1.72-12.34) had significant associations with atopic children. Conclusion: House dust mite Der f 1 concentrations were associated with atopic children. This study suggests that parents should reduce house dust mite Der f 1 concentrations through environmental controls.

Keywords

References

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