Journal of Korean Neurosurgical Society

The Korean Neurosurgical Society (대한신경외과학회)
권호 표지
DOI QR코드

DOI QR Code

Astrocytoma in the Third Ventricle and Hypothalamus Presenting with Parkinsonism

  • Choi, Kang-Ho (Department of Neurology, Chonnam National University Hospital) ;
  • Choi, Seong-Min (Department of Neurology, Chonnam National University Hospital) ;
  • Nam, Tai-Seung (Department of Neurology, Chonnam National University Hwasun Hospital) ;
  • Lee, Min-Cheol (Department of Pathology, Chonnam National University Medical School)
  • Received : 2011.05.12
  • Accepted : 2012.03.12
  • Published : 2012.03.28
Download PDF
⟨ Previous Next ⟩

Abstract

Parkinsonism secondary to intracranial mass lesions usually results from compression or distortion of the basal ganglia. Secondary parkinsonism due to midbrain infiltration or compression is rare and generally associated with other neurologic signs caused by pyramidal tract and/or cranial nerve involvement. We report a case of 30-year-old woman in whom mild parkinsonism was the major clinical manifestation of an astrocytoma in the anterior third ventricle and hypothalamus. She underwent surgical resection, ventriculoperitoneal shunt and radiation therapy. All symptoms of parkinsonism were completely recovered 3 months after the treatment. Brain tumors can be manifested only by the symptoms of parkinsonism. This case emphasizes the significance of neuroimaging in the evaluation of parkinsonism.

Keywords

References

  1. Blocq P, Marinesco G : [Sur un cas tremblement Parkinsonien hemiplegique symptomatique d, une tumeur de pedoncule cerebral]. CR Cos Biol (Paris) 45 : 105-111, 1893
  2. Cicarelli G, Pellecchia MT, Maiuri F, Barone P : Brain stem cystic astrocytoma presenting with "pure" parkinsonism. Mov Disord 14 : 364-366, 1999 https://doi.org/10.1002/1531-8257(199903)14:2<364::AID-MDS1028>3.0.CO;2-I
  3. Gherardi R, Roualdes B, Fleury J, Prost C, Poirier J, Degos JD : Parkinsonian syndrome and central nervous system lymphoma involving the substantia nigra. A case report. Acta Neuropathol 65 : 338-343, 1985 https://doi.org/10.1007/BF00687019
  4. Gouider-Khouja N, Gabsi S, Khouja N, Hentati F : Hemiparkinsonian syndrome due to a cerebral tumor infiltrating the substantia nigra. Parkinsonism Relat Disord 6 : 115-117, 2000 https://doi.org/10.1016/S1353-8020(99)00054-1
  5. Husag L, Wieser HG, Probst C : [Extrapyramidal symptoms in meningiomas.] Schweiz Arch Neurol Neurochir Psychiatr 116 : 257-279, 1975
  6. Krauss JK, Paduch T, Mundinger F, Seeger W : Parkinsonism and rest tremor secondary to supratentorial tumours sparing the basal ganglia. Acta Neurochir (Wien) 133 : 22-29, 1995 https://doi.org/10.1007/BF01404943
  7. Leenders KL, Findley LJ, Cleeves L : PET before and after surgery for tumor-induced parkinsonism. Neurology 36 : 1074-1078, 1986 https://doi.org/10.1212/WNL.36.8.1074
  8. Polyzoidis KS, McQueen JD, Rajput AH, MacFadyen DJ : Parkinsonism as a manifestation of brain tumor. Surg Neurol 23 : 59-63, 1985 https://doi.org/10.1016/0090-3019(85)90161-2
  9. Sypert GW, Leffman H, Ojemann GA : Occult normal pressure hydrocephalus manifested by parkinsonism-dementia complex. Neurology 23 : 234-238, 1973 https://doi.org/10.1212/WNL.23.3.234
  10. Wakai S, Nakamura K, Niizaki K, Nagai M, Nishizawa T, Yokoyama S, et al. : Meningioma of the anterior third ventricle presenting with parkinsonism. Surg Neurol 21 : 88-92, 1984 https://doi.org/10.1016/0090-3019(84)90408-7

Cited by

  1. Intracranial Meningioma-induced Parkinsonism vol.4, pp.2, 2012, https://doi.org/10.15280/jlm.2014.4.2.101
  2. Parkinsonism: a rare manifestation of craniopharyngioma vol.7, pp.2, 2012, https://doi.org/10.14661/2015.1027-1031
  3. A 77‐year‐old man with parkinsonism and rapidly progressive dementia vol.28, pp.5, 2018, https://doi.org/10.1111/bpa.12653
  4. Bidirectional Relation Between Parkinson's Disease and Glioblastoma Multiforme vol.11, pp.None, 2012, https://doi.org/10.3389/fneur.2020.00898
  5. Levodopa-responsive Parkinsonism Caused by Recurrence of Large Basilar-tip Aneurysm after Stent-assisted Coil Embolization: A Case Report vol.8, pp.1, 2012, https://doi.org/10.2176/nmccrj.cr.2020-0023