DOI QR코드

DOI QR Code

Reversibility of Atrioventricular Block According to Coronary Artery Disease: Results of a Retrospective Study

  • Hwang, In-Chang (Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Seo, Won-Woo (Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Oh, Il-Young (Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Choi, Eue-Keun (Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine) ;
  • Oh, Seil (Department of Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine)
  • Published : 2012.12.31

Abstract

Background and Objectives: The causal relationship of clinically-significant atrioventricular block (AVB) and coronary artery disease (CAD) is uncertain. We investigated whether CAD is related to irreversible AVB that requires treatment with a permanent pacemaker. Subjects and Methods: We included 188 consecutive patients with new-onset AVB considering pacemaker, who had undergone invasive or noninvasive coronary evaluation. Patients were divided into one of 2 groups: irreversible AVB who underwent implantation of permanent pacemaker {irreversible block (IB) group, n=173} or reversible AVB {reversible block (RB) group, n=15}. Results: In IB group, significant CAD was observed in 44 patients (25.4%) and there were 2 (1.2%) patients with acute myocardial infarction (AMI). In RB group, 14 patients (93.3%) had CAD (p<0.001) and 13 patients (86.7%) presented with AMI (p<0.001). On the aspect of CAD type and reversibility of AVB, 13/15 (86.7%) patients of AMI, 0/2 (0%) of unstable angina, and 1/41 (2.4%) of stable angina had reversible AVB. Conclusion: AVB in patients with AMI is usually reversible. Therefore, permanent pacemaker implantation should be delayed in cases of AMI. AVB in patients with CAD other than AMI is usually irreversible.

Keywords

References

  1. Mosseri M, Meir G, Lotan C, et al. Coronary pathology predicts conduction disturbances after coronary artery bypass grafting. Ann Thorac Surg 1991;51:248-52. https://doi.org/10.1016/0003-4975(91)90796-S
  2. Mosseri M, Izak T, Rosenheck S, et al. Coronary angiographic characteristics of patients with permanent artificial pacemakers. Circulation 1997;96:809-15. https://doi.org/10.1161/01.CIR.96.3.809
  3. Tandogan I, Yetkin E, Guray Y, et al. Distribution of coronary artery lesions in patients with permanent pacemakers. Anadolu Kardiyol Derg 2002;2:279-83.
  4. Wei S, Zhong L, Chen S, Li X. The status of coronary artery lesions in patients with conduction disturbance. J Cardiovasc Med (Hagerstown) 2011;12:709-13. https://doi.org/10.2459/JCM.0b013e328349187c
  5. Omeroglu SN, Ardal H, Erdogan HB, et al. Can revascularization restore sinus rhythm in patients with acute onset atrioventricular block? J Card Surg 2005;20:136-41. https://doi.org/10.1111/j.0886-0440.2005.200369pl.x
  6. Yesil M, Bayata S, Arikan E, Yilmaz R, Postaci N. Should we revascularize before implanting a pacemaker? Clin Cardiol 2008;31:498-501. https://doi.org/10.1002/clc.20280
  7. Gupta MC, Singh MM, Wahal PK, Mehrotra MP, Gupta SK. Complete heart block complicating acute myocardial infarction. Angiology 1978;29:749-57. https://doi.org/10.1177/000331977802901005
  8. Tans AC, Lie KI, Durrer D. Clinical setting and prognostic significance of high degree atrioventricular block in acute inferior myocardial infarction: a study of 144 patients. Am Heart J 1980;99:4-8. https://doi.org/10.1016/0002-8703(80)90308-7
  9. Nicod P, Gilpin E, Dittrich H, Polikar R, Henning H, Ross J Jr. Long-term outcome in patients with inferior myocardial infarction and complete atrioventricular block. J Am Coll Cardiol 1988;12:589-94. https://doi.org/10.1016/S0735-1097(88)80042-1
  10. Feigl D, Ashkenazy J, Kishon Y. Early and late atrioventricular block in acute inferior myocardial infarction. J Am Coll Cardiol 1984;4:35-8. https://doi.org/10.1016/S0735-1097(84)80315-0
  11. Tjandrawidjaja MC, Fu Y, Kim DH, et al. Compromised atrial coronary anatomy is associated with atrial arrhythmias and atrioventricular block complicating acute myocardial infarction. J Electrocardiol 2005;38:271-8. https://doi.org/10.1016/j.jelectrocard.2005.01.013
  12. Giglioli C, Margheri M, Valente S, et al. Timing, setting and incidence of cardiovascular complications in patients with acute myocardial infarction submitted to primary percutaneous coronary intervention. Can J Cardiol 2006;22:1047-52. https://doi.org/10.1016/S0828-282X(06)70320-8
  13. Van der Hauwaert LG, Stroobandt R, Verhaeghe L. Arterial blood supply of the atrioventricular node and main bundle. Br Heart J 1972;34:1045-51. https://doi.org/10.1136/hrt.34.10.1045
  14. Yesil M, Arikan E, Postaci N, Bayata S, Yilmaz R. Locations of coronary artery lesions in patients with severe conduction disturbance. Int Heart J 2008;49:525-31. https://doi.org/10.1536/ihj.49.525
  15. Iakovou I, Schmidt T, Bonizzoni E, et al. Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. JAMA 2005;293:2126-30. https://doi.org/10.1001/jama.293.17.2126
  16. Tompkins C, Cheng A, Dalal D, et al. Dual antiplatelet therapy and heparin "bridging" significantly increase the risk of bleeding complications after pacemaker or implantable cardioverter-defibrillator device implantation. J Am Coll Cardiol 2010;55:2376-82. https://doi.org/10.1016/j.jacc.2009.12.056
  17. Cano O, Osca J, Sancho-Tello MJ, Olague J, Castro JE, Salvador A. Morbidity associated with three different antiplatelet regimens in patients undergoing implantation of cardiac rhythm management devices. Europace 2011;13:395-401. https://doi.org/10.1093/europace/euq431
  18. Dreger H, Grohmann A, Bondke H, Gast B, Baumann G, Melzer C. Is antiarrhythmia device implantation safe under dual antiplatelet therapy? Pacing Clin Electrophysiol 2010;33:394-9. https://doi.org/10.1111/j.1540-8159.2009.02645.x

Cited by

  1. Reversibility of High-Grade Atrioventricular Block with Revascularization in Coronary Artery Disease without Infarction: A Literature Review vol.2016, pp.None, 2012, https://doi.org/10.1155/2016/1971803
  2. Atrioventricular block after acute myocardial infarction and its association with other clinical parameters in Pakistani patients: an institutional perspective vol.11, pp.None, 2012, https://doi.org/10.1186/s13104-018-3431-5
  3. Reversible Causes of Atrioventricular Block vol.13, pp.4, 2012, https://doi.org/10.1016/j.ccep.2021.07.004