The Korean Journal of Medicine

The Korean Association of Internal Medicine (대한내과학회)
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A Case of Dermatomyositis with Focal Segmental Glomerulosclerosis

피부근염에서 발생한 국소분절사구체경화증 환자 1예

  • Yu, Sung In (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Kim, Min Hee (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Chang, Hyojeong (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Kim, Sang Hyun (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Park, Won Do (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Han, Seong Hoon (Department of Internal Medicine, Sanggye Paik Hospital, Inje University College of Medicine) ;
  • Kim, Hyun Jung (Department of Pathology, Sanggye Paik Hospital, Inje University College of Medicine)
  • 유성인 (인제대학교 의과대학 상계백병원 내과) ;
  • 김민희 (인제대학교 의과대학 상계백병원 내과) ;
  • 장효정 (인제대학교 의과대학 상계백병원 내과) ;
  • 김상현 (인제대학교 의과대학 상계백병원 내과) ;
  • 박원도 (인제대학교 의과대학 상계백병원 내과) ;
  • 한성훈 (인제대학교 의과대학 상계백병원 내과) ;
  • 김현정 (인제대학교 의과대학 상계백병원 병리과)
  • Published : 2012.12.01
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Abstract

A 59-year-old man visited our hospital for facial edema and muscle weakness in both lower extremities. He was diagnosed with dermatomyositis (DM) about 1 year previously, and sudden development of proteinuria was noted. Renal biopsy revealed focal global and segmental glomerulosclerosis with slight mesangial expansion. Glomerulonephritis is rare in DM. According to our review of related literature, membranous nephropathy is the main type of DM, while mesangial proliferative glomerulonephritis is the most common type in polymyositis. The mechanism underlying the association between DM and glomerulonephritis remains to be elucidated. We herein report a case of DM associated with focal segmental glomerulosclerosis, which has not been reported previously.

피부근염에서 신장병변이 나타나는 경우는 주로 횡문근융해로 인한 세뇨관 문제이며 드물게 사구체신염이 나타날 수 있다. 저자들은 국내에 보고된 바 없는 피부근염에 동반된 국소분절사구체경화증을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

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