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다발성 골수종 환자에서 발생한 혈소판 기능 장애

Platelet Dysfunction in a Patient with Multiple Myeloma: A Case Report with a Literature Review

  • 나수영 (울산대학교 의과대학 서울아산병원 내과) ;
  • 박진욱 (울산대학교 의과대학 서울아산병원 내과) ;
  • 최준석 (울산대학교 의과대학 서울아산병원 내과) ;
  • 이대호 (울산대학교 의과대학 서울아산병원 내과) ;
  • 지현숙 (울산대학교 의과대학 서울아산병원 진단검사의학과) ;
  • 이정신 (울산대학교 의과대학 서울아산병원 내과) ;
  • 서철원 (울산대학교 의과대학 서울아산병원 내과)
  • Na, Soo-Young (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Park, Jin Wook (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Choi, Jun Seok (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Lee, Dae Ho (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Chi, Hyun-Sook (Department of Laboratory Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Lee, Jung-Shin (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine) ;
  • Suh, Cheolwon (Department of Internal Medicine, Asan Medical Center, University of Ulsan Collage of Medicine)
  • 발행 : 2012.12.01

초록

Multiple myeloma is a monoclonal plasma cell proliferation disorder with various symptoms and signs caused by paraproteinemias. Among these signs, a bleeding tendency is one of the major fatal causes. However, significant severe bleeding is rare in most cases. In this study, we report a case of multiple myeloma in a patient who had a severe recurrent bleeding tendency due to platelet dysfunction caused by paraproteins. After being treated with therapeutic plasma exchange and chemotherapy, the patient's monoclonal protein level decreased and the bleeding stopped.

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참고문헌

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