DOI QR코드

DOI QR Code

A Case of Emphysematous Cholecystitis and Pneumobilia after Transarterial Chemoembolization for Hepatocellular Carcinoma

간동맥화학색전술 후 발생한 기종성 담낭염 및 담도 기종 1예

  • Choi, Gwang Hyeon (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Yoon, Da-Lim (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Jae Kwang (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Lee, Seung-Hoon (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Jin, Young-Joo (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Park, Do Hyun (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine) ;
  • Shim, Ju Hyun (Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine)
  • 최광현 (울산대학교 의과대학 서울아산병원 소화기내과) ;
  • 윤다림 (울산대학교 의과대학 서울아산병원 소화기내과) ;
  • 이재광 (울산대학교 의과대학 서울아산병원 소화기내과) ;
  • 이승훈 (울산대학교 의과대학 서울아산병원 소화기내과) ;
  • 진영주 (울산대학교 의과대학 서울아산병원 소화기내과) ;
  • 박도현 (울산대학교 의과대학 서울아산병원 소화기내과) ;
  • 심주현 (울산대학교 의과대학 서울아산병원 소화기내과)
  • Published : 2012.12.01

Abstract

Transarterial chemoembolization (TACE) is reportedly a useful palliative treatment in patients with unresectable or recurred hepatocellular carcinoma. Post-TACE complications are common; however, acute cholecystitis after TACE is rare. We herein report a case of a 73-year-old woman who presented with emphysematous cholecystitis and pneumobilia following TACE. Computed tomography performed for evaluation of her tumor status before TACE incidentally showed gallbladder and common bile duct stones. After TACE, she complained of severe epigastric pain with a positive Murphy's sign. Computed tomography showed emphysematous cholecystitis and pneumobilia. She was successfully treated with emergent biliary stone removal by endoscopic retrograde cholangiopancreatography.

수술이 불가능하거나 수술 후 재발한 간세포암에 주로 시행되는 간동맥화학색전술은 시행 후 다양한 합병증이 발생 가능하고, 드물게 담낭염이 보고되고 있다. 하지만 기종성 담낭염과 더불어 담도 기종 발생이 보고된 적은 없다. 저자들은 간동맥화학색전술 후 기종성 담남염과 동반된 담도 기 종의 발생을 경험하였고, 내시경적 치료만으로 호전된 증례를 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Keywords

References

  1. Camma C, Schepis F, Orlando A,et al. Transarterial chemoembolization for unresectable hepatocellular carcinoma: meta-analysis of randomized controlled trials. Radiology 2002;224:47-54. https://doi.org/10.1148/radiol.2241011262
  2. Sakamoto I, Aso N, Nagaoki K, et al. Complications associated with transcatheter arterial embolization for hepatic tumors. Radiographics 1998;18:605-619. https://doi.org/10.1148/radiographics.18.3.9599386
  3. Leung DA, Goin JE, Sickles C, Raskay BJ, Soulen MC. Determinants of postembolization syndrome after hepatic chemoembolization. J Vasc Interv Radiol 2001;12:321-326. https://doi.org/10.1016/S1051-0443(07)61911-3
  4. Wagnetz U, Jaskolka J, Yang P, Jhaveri KS. Acute ischemic cholecystitis after transarterial chemoembolization of hepatocellular carcinoma: incidence and clinical outcome. J Comput Assist Tomogr 2010;34:348-353. https://doi.org/10.1097/RCT.0b013e3181caaea3
  5. Liang SN, Liu LL, Su HY, Feng B, Zhao GS, Xu K. Analysis of severe complications after transcatheter arterial chemoembolization for primary hepatocellular carcinoma. Zhonghua Zhong Liu Za Zhi 2008;30:790-792.
  6. Kim HK, Chung YH, Song BC, et al. Ischemic bile duct injury as a serious complication after transarterial chemoembolization in patients with hepatocellular carcinoma. J Clin Gastroenterol 2001;32:423-427. https://doi.org/10.1097/00004836-200105000-00013
  7. Coldwell DM, Hottenstein DW, Ricci JA, Wengert PA. Emphysematous cholecystitis as a complication of hepatic arterial embolization. Cardiovasc Intervent Radiol 1985;8:36-38. https://doi.org/10.1007/BF02552638
  8. Lee HM, Jeffrey RB. Emphysematous pyelonephritis with resultant emphysematous cholecystitis secondary to hematogenous dissemination. Abdom Imaging 1995;20:169-172. https://doi.org/10.1007/BF00201531
  9. Ko YB, Park YS, Lee YU. Acute Emphsematous Cholecystitis following Gastric Surgery. J Korean Surg Soc 1969;11:617-621.
  10. Harley WD, Kirkpatrick RH, Ferrucci JT Jr. Gas in the bile ducts (pneumobilia) in emphysematous cholecystitis. AJR Am J Roentgenol 1978;131:661-663. https://doi.org/10.2214/ajr.131.4.661