The Korean Journal of Medicine

  • 제83권5호
  • /
  • Pages.624-628
  • /
  • 2012
  • /
  • 1738-9364(pISSN)
  • /
  • 2289-0769(eISSN)
대한내과학회 (The Korean Association of Internal Medicine)
권호 표지
DOI QR코드

DOI QR Code

담낭에서 유례한 과립막 세포종 1예

Granular Cell Tumor Originating from Gallbladder

  • 김동규 (가천의과학대학교 길병원 소화기내과) ;
  • 정영걸 (가천의과학대학교 길병원 소화기내과) ;
  • 정동해 (가천의과학대학교 길병원 병리과) ;
  • 김형식 (가천의과학대학교 길병원 영상의학과) ;
  • 권오상 (가천의과학대학교 길병원 소화기내과) ;
  • 김연수 (가천의과학대학교 길병원 소화기내과) ;
  • 김주현 (가천의과학대학교 길병원 소화기내과)
  • Kim, Dong Kyu (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Jung, Young Kul (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Chung, Dong Hae (Department of Pathology, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kim, Hyung Sik (Department of Radiology, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kwon, Oh Sang (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kim, Yun Soo (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science) ;
  • Kim, Ju Hyun (Department of Internal Medicine, Gil Hospital, Gachon University of Medicine and Science)
  • 발행 : 2012.11.01
⟨ 이전 논문 다음 논문 ⟩

초록

Granular cell tumors are rare benign tumors that arise from Schwann cells. They are especially rare in the gallbladder; indeed, only four cases have been reported in the English-language literature. This paper reports a granular cell tumor in the gallbladder and is the first such report in a Korean woman. She was admitted to the hospital with jaundice and fever and was diagnosed with acute hepatitis A. While hospitalized, a well-demarcated round mass was incidentally found in her gallbladder. The acute hepatitis A improved with conservative care, but the mass did not change in size after 4 months. The tumor was resected with the gallbladder during laparoscopic surgery, and was found to be a granular cell tumor. The tumor was composed of sheets or irregular fascicles of large polygonal or spindle cells with plump eosinophilic granular cytoplasm that was immunohistochemically positive for S-100 and neuron-specific enolase and negative for neurofilament.

키워드

참고문헌

  1. Armin A, Connelly EM, Rowden G. An immunoperoxidase investigation of S-100 protein in granular cell myoblastomas: evidence for Schwann cell derivation. Am J Clin Pathol 1983;79:37-44.
  2. Enzinger FM, Weiss SW. Granular cell tumor. In: Enzinger FM, Weiss SW, eds. Soft Tissue Tumors. 3rd ed. St. Louis: Mosby, 1995:864-875.
  3. Butler JD Jr, Brown KM. Granular cell tumor of the extrahepatic biliary tract. Am Surg 1998;64:1033-1036.
  4. Te Boekhorst DS, Gerhards MF, van Gulik TM, Gouma DJ. Granular cell tumor at the hepatic duct confluence mimicking Klatskin tumor: a report of two cases and a review of the literature. Dig Surg 2000;17:299-303. https://doi.org/10.1159/000018858
  5. Patel AJ, Jakate SM. Granular cell tumor of the biliary tract. Gastroenterol Hepatol (N Y) 2010;6:331-336.
  6. Ishii T, Iri H, Yamamoto S, Shinozawa Y, Sudoh M. Granular cell myoblastoma of the gallbladder. Am J Gastroenterol 1977;68:38-44.
  7. Aisner SC, KhanejaS, Ramirez O. Multiple granular cel tumors of the gallbladder and biliary tree: report of a case. Arch Pathol Lab Med 1982;106:470-471.
  8. Yamaguchi K, Kuroki S, Daimaru Y, Hashimoto H, Enjoji M. Granular cell tumor of the gallbladder: report of a case. Acta Pathol Jpn 1985;35:687-691.
  9. Murakata LA, Ishak KG. Expression of inhibin-alpha by granular cell tumors of the gallbladder and extrahepatic bile ducts. Am J Surg Pathol 2001;25:1200-1203. https://doi.org/10.1097/00000478-200109000-00012
  10. Abrikosoff A. Uber myome ausgehend von der guergestreiften willkuerlichen muskulatur. Virchows Arch Pathol Anat 1926;260:215-223. https://doi.org/10.1007/BF02078314
  11. Park JH, Do NY, Cho SI, Choi JY. Granular cell tumor on larynx. Clin Exp Otorhinolaryngol 2010;3:52-55. https://doi.org/10.3342/ceo.2010.3.1.52
  12. Mazur MT, Shultz JJ, Myers JL. Granular cell tumor: immunohistochemical analysis of 21 benign tumors and one malignant tumor. Arch Pathol Lab Med 1990;114:692-696.
  13. Coggins RP. Granular-cell myoblastoma of common bile duct; report of a case with autopsy findings. AMA Arch Pathol 1952;54:398-402.
  14. Tonsi A, Standish R, Desai C, Davidson BR. Granular cell tumour of the bile duct mimicking distal cholangiocarcinoma: one case report and review of the literature. Minerva Chir 2006;61:247-255.
  15. Ordonez NG, Mackay B. Granular cell tumor: a review of the pathology and histogenesis. Ultrastruct Pathol 1999;23:207-222. https://doi.org/10.1080/019131299281545

피인용 문헌

  1. Biliary Granular Cell Tumor vol.49, pp.1, 2015, https://doi.org/10.4132/jptm.2014.10.07