DOI QR코드

DOI QR Code

복통의 진단적 접근

Diagnostic Approach to Abdominal Pain

  • 류한승 (원광대학교 의과대학 내과학교실, 소화기질환연구소) ;
  • 최석채 (원광대학교 의과대학 내과학교실, 소화기질환연구소)
  • Ryu, Han Seung (Department of Internal Medicine and Digestive Disease Research Institute, Wonkwang University College of Medicine) ;
  • Choi, Suck Chei (Department of Internal Medicine and Digestive Disease Research Institute, Wonkwang University College of Medicine)
  • 발행 : 2012.11.01

초록

Abdominal pain is a common chief complaint that brings patients to emergency departments and outpatient offices. The causes of abdominal pain are numerous, ranging from life-threatening to self-limiting disorders. Diagnostic approaches are often difficult because of the nonspecific and overlapping nature of pain, regardless of the underlying cause. A careful medical history taking is the initial diagnostic step. All patients should undergo systematic examinations, regardless of the differential diagnosis suggested by the history. On the basis of the clinical suspicion and laboratory investigations, the physician will consider imaging examinations to help establish the correct diagnosis. Various endoscopic and imaging modalities have important roles in diagnosing many causes of abdominal pain. Diagnostic approaches rely on the likelihood of disease obtaining from histories of patients, physical examinations, laboratory tests, and imaging studies. Furthermore, the evaluation of abdominal pain must be efficient and lead to an accurate diagnosis early in the presentation. It is also important to consider special populations such as women especially during pregnancy and the elderly, because of presentations may differ and are often complicated by coexistent disease.

키워드

참고문헌

  1. Gebhart GF. Visceral pain-peripheral sensitisation. Gut 2000;47(Suppl 4):iv54-iv55.
  2. Bueno L, Fioramonti J, Garcia-Villar R. Pathobiology of visceral pain: molecular mechanisms and therapeutic implications: III. visceral afferent pathways: a source of new therapeutic targets for abdominal pain. Am J Physiol Gastrointest Liver Physiol 2000;278:G670-G676.
  3. Bradley WG, Daroff RB, Fenichel GM, Jankovic J. Neurology in Clinical Practice. 5th ed. Philadelphia: Butterworth- Heinemann, 2008.
  4. Feldman M, Friedman LS, Brandt LJ. Feldman: Sleisinger & Fordtran's Gastrointestinal and Liver Disease. 9th ed. Philadelphia: Saunders Elsevier, 2010.
  5. Akbar A, Walters JR, Ghosh S. Review article: visceral hypersensitivity in irritable bowel syndrome: molecular mechanisms and therapeutic agents. Aliment Pharmacol Ther 2009;30:423-435. https://doi.org/10.1111/j.1365-2036.2009.04056.x
  6. Anand P, Aziz Q, Willert R, van Oudenhove L. Peripheral and central mechanisms of visceral sensitization in man. Neurogastroenterol Motil 2007;19(1 Suppl):S29-S46.
  7. Delgado-Aros S, Camilleri M. Visceral hypersensitivity. J Clin Gastroenterol 2005;39(5 Suppl 3):S194-S203.
  8. Delvaux M. Role of visceral sensitivity in the pathophysiology of irritable bowel syndrome. Gut 2002;51(Suppl 1):i67-i71.
  9. Knowles CH, Aziz Q. Visceral hypersensitivity in non-erosive reflux disease. Gut 2008;57:674-683. https://doi.org/10.1136/gut.2007.127886
  10. Cartwright SL, Knudson MP. Evaluation of acute abdominal pain in adults. Am Fam Physician 2008;77:971-978.
  11. Irvin TT. Abdominal pain: a surgical audit of 1190 emergency admissions. Br J Surg 1989;76:1121-1125. https://doi.org/10.1002/bjs.1800761105
  12. Wagner JM, McKinney WP, Carpenter JL. Does this patient have appendicitis? JAMA 1996;276:1589-1594. https://doi.org/10.1001/jama.1996.03540190061030
  13. Kessler N, Cyteval C, Gallix B, et al. Appendicitis: evaluation of sensitivity, specificity, and predictive values of US, Doppler US, and laboratory findings. Radiology 2004;230:472-478. https://doi.org/10.1148/radiol.2302021520
  14. Andersson RE. Meta-analysis of the clinical and laboratory diagnosis of appendicitis. Br J Surg 2004;91:28-37. https://doi.org/10.1002/bjs.4464
  15. Johansson EP, Rydh A, Riklund KA. Ultrasound, computed tomography, and laboratory findings in the diagnosis of appendicitis. Acta Radiol 2007;48:267-273. https://doi.org/10.1080/02841850601182162
  16. Andersson RE. The natural history and traditional management of appendicitis revisited: spontaneous resolution and predominance of prehospital perforations imply that a correct diagnosis is more important than an early diagnosis. World J Surg 2007;31:86-92. https://doi.org/10.1007/s00268-006-0056-y
  17. Trowbridge RL, Rutkowski NK, Shojania KG. Does this patient have acute cholecystitis? JAMA 2003;289:80-86. https://doi.org/10.1001/jama.289.1.80
  18. Hirota M, Takada T, Kawarada Y, et al. Diagnostic criteria and severity assessment of acute cholecystitis: Tokyo Guidelines. J Hepatobiliary Pancreat Surg 2007;14:78-82. https://doi.org/10.1007/s00534-006-1159-4
  19. Shea JA, Berlin JA, Escarce JJ, et al. Revised estimates of diagnostic test sensitivity and specificity in suspected biliary tract disease. Arch Intern Med 1994;154:2573-2581. https://doi.org/10.1001/archinte.1994.00420220069008
  20. Bree RL, Ralls PW, Balfe DM, et al. Evaluation of patients with acute right upper quadrant pain: American College of Radiology: ACR Appropriateness Criteria. Radiology 2000; 215(Suppl):S153-S157.
  21. Choi CS, Cho EY, Kweon JH, et al. The prevalence and clinical features of colonic diverticulosis diagnosed with colonscopy. Korean J Gastrointest Endosc 2007;35:146-151.
  22. Jacobs DO. Clinical practice: diverticulitis. N Engl J Med 2007;357:2057-2066. https://doi.org/10.1056/NEJMcp073228
  23. Whitcomb DC. Clinical practice: acute pancreatitis. N Engl J Med 2006;354:2142-2150. https://doi.org/10.1056/NEJMcp054958
  24. Arvanitakis M, Delhaye M, De Maertelaere V, et al. Computed tomography and magnetic resonance imaging in the assessment of acute pancreatitis. Gastroenterology 2004;126:715-723. https://doi.org/10.1053/j.gastro.2003.12.006
  25. Romagnuolo J, Currie G; Calgary Advanced Therapeutic Endoscopy Center study group. Noninvasive vs. selective invasive biliary imaging for acute biliary pancreatitis: an economic evaluation by using decision tree analysis. Gastrointest Endosc 2005;61:86-97. https://doi.org/10.1016/S0016-5107(04)02472-1
  26. Batke M, Cappell MS. Adynamic ileus and acute colonic pseudo-obstruction. Med Clin North Am 2008;92:649-670. https://doi.org/10.1016/j.mcna.2008.01.002
  27. Maglinte DD, Balthazar EJ, Kelvin FM, Megibow AJ. The role of radiology in the diagnosis of small-bowel obstruction. AJR Am J Roentgenol 1997;168:1171-1180. https://doi.org/10.2214/ajr.168.5.9129407
  28. Taourel PG, Fabre JM, Pradel JA, Seneterre EJ, Megibow AJ, Bruel JM. Value of CT in the diagnosis and management of patients with suspected acute small-bowel obstruction. AJR Am J Roentgenol 1995;165:1187-1192. https://doi.org/10.2214/ajr.165.5.7572500
  29. Sung JJ, Kuipers EJ, El-Serag HB. Systematic review: the global incidence and prevalence of peptic ulcer disease. Aliment Pharmacol Ther 2009;29:938-946. https://doi.org/10.1111/j.1365-2036.2009.03960.x
  30. Higham J, Kang JY, Majeed A. Recent trends in admissions and mortality due to peptic ulcer in England: increasing frequency of haemorrhage among older subjects. Gut 2002;50:460-464. https://doi.org/10.1136/gut.50.4.460
  31. Stapakis JC, Thickman D. Diagnosis of pneumoperitoneum: abdominal CT vs. upright chest film. J Comput Assist Tomogr 1992;16:713-716. https://doi.org/10.1097/00004728-199209000-00008
  32. Chang RW, Chang JB, Longo WE. Update in management of mesenteric ischemia. World J Gastroenterol 2006;12:3243-3247.
  33. Zalcman M, Sy M, Donckier V, Closset J, Gansbeke DV. Helical CT signs in the diagnosis of intestinal ischemia in small-bowel obstruction. AJR Am J Roentgenol 2000;175:1601-1607. https://doi.org/10.2214/ajr.175.6.1751601
  34. Mayer EA, Naliboff BD, Chang L. Basic pathophysiologic mechanisms in irritable bowel syndrome. Dig Dis 2001;19:212-218. https://doi.org/10.1159/000050682
  35. Han SH, Lee OY, Bae SC, et al. Prevalence of irritable bowel syndrome in Korea: population-based survey using the Rome II criteria. J Gastroenterol Hepatol 2006;21:1687-1692. https://doi.org/10.1111/j.1440-1746.2006.04269.x
  36. Steer ML, Waxman I, Freedman S. Chronic pancreatitis. N Engl J Med 1995;332:1482-1490. https://doi.org/10.1056/NEJM199506013322206
  37. Bicanovsky LK, Lagman RL, Davis MP, Walsh D. Managing nonmalignant chronic abdominal pain and malignant bowel obstruction. Gastroenterol Clin North Am 2006;35:131-142. https://doi.org/10.1016/j.gtc.2006.01.002
  38. Layer P, Yamamoto H, Kalthoff L, Clain JE, Bakken LJ, DiMagno EP. The different courses of early- and late-onset idiopathic and alcoholic chronic pancreatitis. Gastroenterology 1994;107:1481-1487. https://doi.org/10.1016/0016-5085(94)90553-3
  39. Etemad B, Whitcomb DC. Chronic pancreatitis: diagnosis, classification, and new genetic developments. Gastroenterology 2001;120:682-707. https://doi.org/10.1053/gast.2001.22586
  40. Lindsetmo RO, Stulberg J. Chronic abdominal wall pain: a diagnostic challenge for the surgeon. Am J Surg 2009;198:129-134. https://doi.org/10.1016/j.amjsurg.2008.10.027
  41. Fenyo G. Acute abdominal disease in the elderly: experience from two series in Stockholm. Am J Surg 1982;143:751-754. https://doi.org/10.1016/0002-9610(82)90052-6
  42. Kizer KW, Vassar MJ. Emergency department diagnosis of abdominal disorders in the elderly. Am J Emerg Med 1998;16:357-362. https://doi.org/10.1016/S0735-6757(98)90127-9
  43. Augustin G, Majerovic M. Non-obstetrical acute abdomen during pregnancy. Eur J Obstet Gynecol Reprod Biol 2007;131:4-12. https://doi.org/10.1016/j.ejogrb.2006.07.052
  44. Kilpatrick CC, Orejuela FJ. Management of the acute abdomen in pregnancy: a review. Curr Opin Obstet Gynecol 2008;20:534-539. https://doi.org/10.1097/GCO.0b013e328317c735

피인용 문헌

  1. Functional abdominal pain syndrome treated with Korean medication vol.3, pp.2, 2014, https://doi.org/10.1016/j.imr.2013.12.004
  2. Clinical Approach to Abdominal Pain as Functional Origin vol.71, pp.2, 2012, https://doi.org/10.4166/kjg.2018.71.2.89
  3. 응급의료센터에 내원한 복부통증 노인 환자에 대한 간호기록 분석 vol.26, pp.1, 2012, https://doi.org/10.5953/jmjh.2019.26.1.27