Journal of Korean Biological Nursing Science

Korean society of Biological Nursing Science (한국기초간호학회)
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Perceptions of Anticoagulation Therapy and Medication Adherence among Patients taking Warfarin

와파린 복용 환자의 항응고요법에 대한 인식과 약물복용 이행

  • Chu, Sang-Hui (College of Nursing, Division of Clinical Nursing Science.Nursing Policy and Research Institute, Yonsei University) ;
  • Kang, Seok-Min (College of Medicine, Division of Cardiology, Yonsei University) ;
  • Kim, Do-Ree (Bobath Memorial Hospital) ;
  • Lee, Yoon-Ju (College of Nursing, Division of Clinical Nursing Science, Yonsei University)
  • 추상희 (연세대학교 간호대학 임상간호과학과.간호정책연구소) ;
  • 강석민 (연세대학교 의과대학 심장내과) ;
  • 김두리 (보봐스병원) ;
  • 이윤주 (연세대학교 간호대학 임상간호과학과)
  • Received : 2012.03.30
  • Accepted : 2012.04.13
  • Published : 2012.04.30
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Abstract

Purpose: This study was conducted to measure medication adherence and perceptions of anticoagulation therapy and its relationship to patients taking warfarin. Methods: in a cross-sectional survey, 150 patients taking warfarin who had visited an outpatient clinic of a cardiovascular center in Seoul were included as research subjects. Medication adherence was measured using a visual analogue rating scale (VAS). Barriers and attitudes toward adherence, and oral anticoagulation knowledge, were measured using a structured questionnaire. Participants' medical records also were reviewed to identify clinical characteristics. Results: About one third of the participants (30.7%) reported medication adherence as 100%. The major barriers to adherence were identified as "Forgetting the time of medication" and "Not carrying their medication". Overall attitudes toward medication adherence were high, but oral anticoagulation therapy knowledge was low. To determine the relationship of medication adherence and perceptions of anticoagulation therapy, participants were stratified into three groups, based on their medication adherence levels (high adherence, moderate adherence, low adherence). Participants in the high adherent group more likely to be older (OR: 1.04, 95% CI: 1.005-1.071) and to have positive attitudes toward medication adherence (OR: 1.12, 95% CI:1.013-1.229) compared to the other two groups. Conclusion: The results show that age and attitude exerts significant influence on medication adherence in patients taking warfarin.

Keywords

References

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