The Influence of Office Indoor Air Qualitys on the Dry Eye Symptom of Contact Lens Wearers

사무실 실내공기질과 콘택트렌즈 착용여부가 안구 건조증에 미치는 영향

  • Kim, Dea Jong (Dept. of Ophthalmic Optics, Shinheung College University) ;
  • Park, Moon Chan (Dept. of Ophthalmic Optics, Shinheung College University) ;
  • Lee, Se Hoon (Dept. of Prev. Med, College of Medicine, The Catholic University) ;
  • Kim, Hyun Uk (Dept. of Prev. Med, College of Medicine, The Catholic University) ;
  • Lee, Wha Ja (Dept. of Nursing, Kyungbok College University) ;
  • Cha, Jung Won (Dept. of Ophthalmic Optics, Shinheung College University)
  • 김대종 (신흥대학교 안경광학과) ;
  • 박문찬 (신흥대학교 안경광학과) ;
  • 이세훈 (가톨릭대학교 의과대학 예방의학교실) ;
  • 김현욱 (가톨릭대학교 의과대학 예방의학교실) ;
  • 이화자 (경복대학교 간호학과) ;
  • 차정원 (신흥대학교 안경광학과)
  • Received : 2012.02.03
  • Accepted : 2012.06.16
  • Published : 2012.06.30

Abstract

Purpose: This study was performed to investigate the influence of indoor air qualities of an office environment on dry eye syndrome for wearing contact lens and non-wearing contact lens. Methods: To study the effects of indoor air qualities on dry eye syndrome for seventy-one subjects, $CO_2$, temperature, humidity, TSP, PM10, HCHO were measured. Each subject was tested by a McMonnie's dry eye syndrome questionnaire, a Schirmer Tear Test-I (S.T.T-I), a Schirmer Tear Test-II with anesthetics (S.T.T-II), and Tear film break-up time (T.B.U.T) in the their offices. Results: There was significant relation between the indoor air quality and dry eye syndrome for wearing contact lens and non-wearing when TSP was over $200{\mu}g/m^3$, PM10 was higher than $86.7{\mu}g/m^3$ and Formaldehyde was over $0.4{\sim}1.0{\mu}g/m^3$. However, there was no significant effect on dry eye syndrome with $CO_2$ (p=.0146), temperature (p=0.074) and humidity (p=0.053). Conclusions: It was indicated that $CO_2$, temperature and humidity were no effect on dry eye syndrome in the office environment. However TSP, PM10, formaldehyde, and wearing contact lens were effect on dry eye syndrome. Therefore, the entire management of wearing contact lens and the individual evaluation of the indoor air quality are required.

목적: 본 연구는 콘택트렌즈 착용 여부와 사무실 실내공기질이 안구건조에 미치는 영향이 있는지 파악하고자 하였다. 방법: 71명의 연구 대상자들의 각 사무실에서 실내공기질이 안구건조에 미치는 영향을 파악하기 위하여 이산화탄소($CO_2$), 온도(temperature), 습도(relative humidity), 총 부유분진(TSP), 미세먼지($PM_{10}$), 포름알데히드(HCHO)를 측정분석 하였고, 안구 건조증을 확인하기 위하여 연구 대상자들의 사무실에서 McMonnies dry eye symptom questionnaire, Schirmer Tear Test-I(S.T.T-I), Schirmer Tear Test-II with anesthetics(S.T.T-II), Tear film break-up time(T.B.U.T) 등을 검사 하였다. 결과: 콘택트렌즈 착용여부에 따라 사무실 실내공기질이 안구건조증에 영향을 미치는 요인으로는 TSP는 $200{\mu}g/m^3$, $PM_{10}$$86.7{\mu}g/m^3$, 포름알데히드는 $0.4{\sim}1.0{\mu}g/m^3$을 기준으로 농도가 높게 측정되었을 때 유의한 관련성이 있는 것으로 분석되었다. 그러나 $CO_2$(p=0.146), 온도(p=0.074)와 습도(p=0.053)는 통계적으로 안구건조와 유의한 관련성이 없는 것으로 분석되었다. 결론: 사무실 재실자의 안구 건조에 $CO_2$ 및 온도, 습도는 유의한 영향이 없었으나, TSP, $PM_{10}$, 포름알데히드의 실내 농도와 콘택트렌즈의 착용여부는 관련이 있었다. 콘택트렌즈 착용에 대한 종합적인 관리와 사무실 실내공기의 개별적인 평가가 함께 이루어져야 하겠다.

Keywords

References

  1. Howard S. Sick building syndrome studies and the compilation of normative and comparative values. In: Spengler JD, Samet JM, McCarthy JF. Indoor Air Quality Handbook, 1st Ed. NY: Mcgraw Hill, 2000;3.1-3.32.
  2. Lemp MA. Report of the national eye institute/industry workshop on clinical trials of dry eye. CLAO J. 1995;21(4):221-232.
  3. The Korean External Eye Disease Society. Cornea, 2nd Ed. Seoul: Ilchokak, 2005;211-220.
  4. Narayanan S, Miller WL, Prager TC, Jackson JA, Leach NE, McDermott AM, et al. The diagnosis and characteristics of moderate dry eye in non-contact lens wearers. Eye Contact Lens. 2005;31(3):96-104. https://doi.org/10.1097/01.ICL.0000140907.45705.E2
  5. Wolkoff P, Nojgaard JK, Troiano P, Piccoli B. Eye complaints in the office environment: precorneal tear film integrity influenced by eye blinking effciency. Occup Environ Med. 2005;62(1):4-12. https://doi.org/10.1136/oem.2004.016030
  6. Farris RL. The dry eye: its mechanisms and therapy, with evidence that contact lens is a cause. CLAO J. 1986;12(4):234-246.
  7. Akbar-Khanzadeh F, Vaquerano MU, Akbar-Khanzadeh M, Bisesi MS. Formaldehyde exposure, acute pulmonary response, and exposure control options in a gross anatomy laboratory. Am J Ind Med. 1994;26(1):61-75. https://doi.org/10.1002/ajim.4700260106
  8. Bender JR, Mullin LS, Graepel GJ, Wilson WE. Eye irritation response of humans to formaldehyde. Am Ind Hyg Assoc J. 1983;44(6):463-465. https://doi.org/10.1080/15298668391405139
  9. Takigawa T, Usami M, Yamasaki Y, Wang B, Sakano N, Horike T, et al. Reduction of indoor formaldehyde concentrations and subjective symptoms in a gross anatomy laboratory. Bull Environ Contam Toxicol. 2005;74(6):1027-1033. https://doi.org/10.1007/s00128-005-0683-2
  10. Wolkoff P, Nøjgaard JK, Franck C, Skov P. The modern office environment desiccates the eye?. Indoor Air. 2006;16(4):258-265. https://doi.org/10.1111/j.1600-0668.2006.00429.x
  11. Tsubota K, Kaido M, Yagi Y, Fujihara T, Shimmura S. Diseases associated with ocular surface abnormalities: the importance of reflex tearing. Br J Opthalmol. 1999;83(1):89-91. https://doi.org/10.1136/bjo.83.1.89
  12. Doughty MJ, Blades KA, lbrahim N. Assessment of the number of eye symptoms and impact of some confounding variables for office staff in non-air-conditioned buildings. Ophthal Physiol Opt. 2002;22(2):143-155. https://doi.org/10.1046/j.1475-1313.2002.00013.x
  13. McMonnies CW. Key questions in a dry eye history. J Am Optom Assoc. 1986;57(7):512-517.
  14. Kim SA. A study of Conjunctival Celluar Changes in Dry Eye Patients and Contact Lens Wearers by Impression Cytology. Master Thesis. Chonnam University, Gwangju. 2004;1-38.
  15. Molhave L, Krzyzanowski M. The right to healthy indoor air: status by 2002. Indoor Air. 2003;13(6):50-53.
  16. Smedbold HT, Ahlen C, Norback D, Hilt B. Sign of eye irritation in female hospital workers and the indoor environment. Indoor Air. 2001;11(4):223-231. https://doi.org/10.1034/j.1600-0668.2001.110403.x
  17. Jin KH. Worsen in the winter of the dry eye. J Kyung Hee Univ Cent Vol. 2006;11:6-7.
  18. Koo JW, Lee JY, Lee SH. Subjective eye symtoms due to VDT work in banking operations. Korean J Occup Environ Med. 1991;30(4):89-94.
  19. Grun G, Trimmel M, Holm A. Low Humidity in the aircraft cabin environment and its impact on well-beingresults from a laboratory study. Building and Environment. 2012;47:23-31.
  20. Ong BL. Relation between contact lens wear and meibomian gland dysfunction. Optom Vis Sci. 1996;73(3):208-210. https://doi.org/10.1097/00006324-199603000-00015
  21. Young G, Veys J, Pritchard N, Coleman S. A multi-centre study of lapsed contact lens wearers. Ophthal Physiol Opt. 2002;22(6):516-527. https://doi.org/10.1046/j.1475-1313.2002.00066.x
  22. Uras R, Lipener C, Zamboni FJ, Nagoya FR, Leca R, Lewinski R. Clinical study of disposable contact lens wear: Brazilian experience. CLAO J. 1996;22(2):102-105.
  23. Ministry of Employment and Labor. Office of Indoor Air Quality Management System. 2005;6-15.
  24. Erdmann CA, Steiner KC, Apte MG. Indoor carbon dioxide concentrations and sick building syndrome symtoms in the base study revisited: analyses of the 100 building dataset. Indoor Air. 2002;443-448.
  25. Ministry of Environment. Indoor Air Quality Management. 2006;11-16.
  26. Smedbold HT, Ahlen C, Norbäck D, Hilt B. Sign of eye irritation in female hospital workers and the indoor environment. Indoor Air. 2001;11(4):223-231. https://doi.org/10.1034/j.1600-0668.2001.110403.x
  27. Park SY, Kim CY, Kim JY, Sakong J. The health effects of formaldehyde during an anatomy dissection course. Korean J Occup Environ Med. 2006;18(3):171-178.
  28. Krakowiak A, Grski P, Pazdrak K, Ruta U. Airway response to formaldehyde inhalation in asthmatic subjects with suspected respiratory formaldehyde sensitization. Am J Ind Med. 1998;33(3):274-281. https://doi.org/10.1002/(SICI)1097-0274(199803)33:3<274::AID-AJIM9>3.0.CO;2-W