The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology (한방안이비인후피부과학회지)

The Society of Korean Medicine Ophthalmology, Otolaryngology & Dermatology (대한한방안이비인후피부과학회)
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A clinical study for effect of a supplement(Bee Larva) in subjects with tinnitus

벌유충 분말 서플리먼트의 이명에 대한 임상적 연구

  • Kang, Da-Hae (Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology, Semyung University Oriental Medical Hospital) ;
  • O, Min-Ji (Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology, Semyung University Oriental Medical Hospital) ;
  • Kim, Hee-Taek (Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology, Semyung University Oriental Medical Hospital)
  • 강다혜 (세명대학교 한의과대학 안이비인후피부과학교실) ;
  • 오민지 (세명대학교 한의과대학 안이비인후피부과학교실) ;
  • 김희택 (세명대학교 한의과대학 안이비인후피부과학교실)
  • Received : 2012.04.16
  • Accepted : 2012.05.10
  • Published : 2012.05.25
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Abstract

Objectives : The primary purpose of present study is to evaluate the effect of a supplement of Bee Larva on tinnitus. the second is to comparatively evaluate safety of this supplement. Methods : Among those patients who visited Semyung Oriental Medical Center from January 11st, 2010 to February 20th, 2010, we screened 45 patients considered suitable for this study after some examinations and consent of the patients. they were devided into 2 groups. Group A took 5 tablets of this supplement everyday for 4 weeks, group B, placebo, in the same way. for 4 weeks, we checked changes in intensity, duration, extent of tinnitus on daily life and sleep and THI(Tinnitus Handicap Inventory) score. to evaluate safety of this supplement, adverse events, assessment of vital sign, hematologic examination were recorded. Result : Through 4 weeks of the clinical trial, we found that this supplement is effective on tinnitus and it improves intensity, duration and extent (its influence on daily life) of tinnitus, influence of tinnitus on sleep and THI score more effectively than the placebo drug. Also, in the assessment of the safety of the study the supplement of bee Larva and placebo drug, there were no adverse events and side effects over the average which need treatment for it. Moreover, there were not any abnormal findings in change of blood pressure and hematologic examination. Conclusion : According to this experiment, we confirmed that the supplement of bee Larva can be used effectively and safely on tinnitus.

Keywords

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