A Case of Central Pontine Myelinolysis after Alcohol drinking

음주 후 발생한 중심성뇌교수초용해증의 치료 1례

  • Lee, Sung-Jong (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Baek, In-Kyoung (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Cho, Chang-Hwan (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Ahn, Jung-Jo (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Cho, Hyun-Kyoung (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Yoo, Ho-Ryong (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Seol, In-Chan (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University) ;
  • Kim, Yoon-Sik (Dept. of Internal Medicine, College of Oriental Medicine, Daejeon University)
  • 이성종 (대전대 둔산한방병원 뇌신경센터) ;
  • 백인경 (대전대 둔산한방병원 뇌신경센터) ;
  • 조창환 (대전대 둔산한방병원 뇌신경센터) ;
  • 안정조 (대전대 둔산한방병원 뇌신경센터) ;
  • 조현경 (대전대 둔산한방병원 뇌신경센터) ;
  • 유호룡 (대전대 둔산한방병원 뇌신경센터) ;
  • 설인찬 (대전대 둔산한방병원 뇌신경센터) ;
  • 김윤식 (대전대 둔산한방병원 뇌신경센터)
  • Received : 2011.11.08
  • Accepted : 2012.02.16
  • Published : 2012.02.20

Abstract

Objective: The purpose of this study was to show the effects Oriental medicine and treatment for aftereffects of Central pontine myelinolysis (CPM). Methods: The 52-year-old woman suffering from CPM showed symptoms of weakness of both extremities, dysarthria, dysphagia and gait disturbance. We treated the patient with oriental medical therapy. Results: After the treatments, overall symptoms of CPM were improved. Conclusions: This study suggests that oriental medical therapy is probably effective in the treatment of CPM.

Keywords

References

  1. Adams RD, Victor M, Mancall EL. Central pontine myelinolysis : a hitherto undescribed disease occurring in alcoholics and malnourished patients. Arch Neurol Psychiatry 81:154-172, 1959 https://doi.org/10.1001/archneurpsyc.1959.02340140020004
  2. Schroth G. Clinical and CT confirmed recovery from central pontine myelinolysis. Neuroradiology 26:149-151, 1984 https://doi.org/10.1007/BF00339865
  3. Monseu Gm, Flament-Durand J: Pathogenesis of central pontine myelinolysis: a clinical and pathological description of three cases. Pathol Eur 6: 75-94, 1971
  4. Shintani S, Tsuruoka S, Shiigai T. Hypoglycaemic hemiplegia : a repeat SPECT Study. J Neurol Neurosurg Psychiatry 56:700-701, 1993 https://doi.org/10.1136/jnnp.56.6.700
  5. 대한신경과학회. 신경학. 군자출판사; 17:610, 2007
  6. 김훈, 이석우. 금주 후 저나트륨혈증 없이 발생한 교뇌중심부 및 교뇌외수초용해증 1례. 대한응급의학회지. 2006;17(6):652-5.
  7. Mast H, Gordon PH, Mohr JP, Tatemichi TK. Central pontine myelinolysis: clinical syndrome with normal serum sodium. Eur J Med Res 1995;1:168-70.
  8. 김수연, 최가연, 선승호. 만성 알콜중독증 환자에서 발생한 중심성 뇌교 수초용해증 치험 1례. 대한한방내과학회지 30(3) 639-647, 2009
  9. 전국한의과대학 심계내과학교실. 한방 순환․ 신경내과학. 군자출판사; 331, 2010
  10. 신재용. 방약합편해설. 성보사; 30, 60, 67, 99, 100, 149, 1988
  11. 대한침구학회교재편찬위원회, 침구학(상), 집문당, 2008, 경기도, 105, 202, 249-250, 346p
  12. Milionis HJ, Liamis GL, Elisaf MS. Hyperosmolar syndrome in a patient with uncontrolled diabetes mellitus. Am J Kidney Dis 37:E41. 2001 https://doi.org/10.1016/S0272-6386(01)90001-0
  13. Brown WD. Osmotic demyelination disorder : central pontine and extrapontine myelinolysis. Curr Opin Neurol 13:691-7, 2000 https://doi.org/10.1097/00019052-200012000-00014
  14. Hiehle JF Jr, Lenkinski RE, Grossman RI, Dousset V, Ramer KN, Schall MD, Cohen, Gonzalez-Scarano F. Correlation of spectroscopy and magnetization transfer imaging in the evaluation of demyelinating lesions and normal appearing white matter in multiple sclerosis. Magn Reson Med 32:285-93, 1994 https://doi.org/10.1002/mrm.1910320303
  15. Strub MU, Steck AJ, Fuhr P. Asymptomatic central pontine myelinolysis. Neurology 53:914, 1999 https://doi.org/10.1212/WNL.53.5.914
  16. 허준. 동의보감. 여강; 1360-1369, 2005