Journal of Haehwa Medicine (혜화의학회지)

Research Institute of Korean Medicine (대전대학교 한의학연구소)
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Effects of Vanadium Water on Cancer-related Fatigue of Non Advanced Thyroid Cancer Patients: Randomized, Three armed, Triple Blinded Controlled Trial

비진행성 갑상선암 환자에 대한 제주워터의 항피로 효능에 대한 유효성과 안전성 평가 예비 임상연구 - 무작위배정, 이중맹검, 삼군위약대조군 연구

  • Zheng, Hong-Mei (East-West Cancer Center, Dunsan Oriental Hospital, Daejeon University) ;
  • Kim, Dong-Hee (Dept. of Oriental Pathology, College of Oriental Medicine, Daejeon University) ;
  • Lee, Suk-Hoon (Dept. of Statistics, Graduate School Chungnam National University) ;
  • Kim, Kyung-Soon (East-West Cancer Center, Dunsan Oriental Hospital, Daejeon University) ;
  • Yoo, Hwa-Seung (East-West Cancer Center, Dunsan Oriental Hospital, Daejeon University)
  • Received : 2011.09.27
  • Accepted : 2012.01.03
  • Published : 2012.02.20
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Abstract

Objective : This study was conducted to evaluate of efficacy and safety of Vanadium Water (VW) on Cancer related Fatigue of Non-advanced Cancer Patients. Methods : Experimental Group Administration. Participants in treatment group consumed three 500 ml/bottle bottles of Jeju Island's VW, which contains 40.2 ${\mu}g/L$ of vanadium, three times a day (morning, afternoon, evening) for 4 weeks (28 days) without any additional treatments for fatigue improvement. The control group participants consumed three 500 ml/bottle bottles of ordinary water (0 ${\mu}g/L$ of vanadium) three times a day for the same period of time without any additional treatments for fatigue improvement. Results : After 4 weeks of VW consumption, total score of Revised Piper Fatigue Scale (RPFS) was reduced 30% and basal score after Fisher's Exact Test resulted statistical borderline significance (p=0.0799) and result of t-test of comparison between two groups' RPFS total score and fatigue cognitive/mood changes resulted statistical significance (p=0.0112). In detail, only 36.4% of control group (N=11) showed improvement while 77.8% of treatment group (N=9) showed fatigue improvement and thyroid hormone level changes. No other lab measures indicated any significant differences between two groups. Conclusion : Daily consumption of 1.5 L of Vanadium water for 4 weeks showed improvement of non-advanced cancer patients' fatigue.

Keywords

References

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