Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
권호 표지

A Case of Dermal Apocrine Gland Adenocarcinoma on the Axillary Region in a Maltese Dog

말티즈견에서 발생한 액와부 피부 아포크린 샘암종 1례

  • Kim, Ju-Won (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University) ;
  • Choi, Young-Chul (Africa Animal Medical Center) ;
  • Sur, Jung-Hyang (Department of Veterinary Pathology,College of Veterinary Medicine, Konkuk University)
  • 김주원 (건국대학교 수의과대학 수의내과학교실) ;
  • 최영철 (아프리카 동물메디컬센터) ;
  • 서정향 (건국대학교 수의과대학 수의병리학교실)
  • Accepted : 2012.01.25
  • Published : 2012.02.29
Download PDF
⟨ Previous Next ⟩

Abstract

A 15-year-old, spayed-female Maltese dog was presented with history of erythema and pruritus in left axillary region. In physical examination, firm elevated erythematous lesions were distributed throughout the axillary lesion. Fine needle aspiration cytology showed neoplastic epithelial cells with anisocytosis, high N:C ratio, and prominent nucleoli. Histologically, this lesion was consisted of a proliferation of undifferentiated neoplastic cells with eosinophilic cytoplasm. Mitotic figures of the neoplastic cells were observed and the neoplastic cells were intensely positive for cytokeratin. The presenting tumor was diagnosed as dermal apocrine gland adenocarcinoma.

Keywords

References

  1. 이준상, 유민영, 김홍용, 김한욱, 임철완. 액와부에서 발생한 아포크린 선암 1예. 대한피부과학회지 2000; 38: 514-517.
  2. Gulbahar MY, Alkan I, Aslan L, Golen I. Mixed apocrine sweat gland tumor of the tail in a cow. Vet Pathol 2002; 39: 281-285.
  3. Hirai T, Mubarak M, Kimura T, Ochiai K, Itakura C. Apocrine gland tumor of the eyelid in a dog. Vet Pathol 1997; 34: 232- 234. https://doi.org/10.1177/030098589703400310
  4. Kalaher KM, Anderson WI, Scott DW. Neoplasms of the apocrine sweat glands in 44 dogs and 10 cats. Vet Rec 1990; 127: 400-403.
  5. Kato K, Uchida K, Nibe K, Tateyama S. Immunohistochemical studies on cytokeratin 8 and 18 expressions in canine cutaneous adnexus and their tumors. J Vet Med Sci 2007; 69: 233-239. https://doi.org/10.1292/jvms.69.233
  6. Meuton DJ. Apocrine and modified apocrine gland tumors. In: Tumors in domestic animals. 4th ed. Iowa: Iowa State Press. 2002: 70-76.
  7. Morrison WB. Tumors of the skin and subcutis. In: Cancer in dogs and cats. 2nd ed. Wyoming: Tenton NewMedia. 2002: 461-488.
  8. Nibe K, Uchida K, Itoh T, Tateyama S. A case of canine apocrine sweat gland adenoma, clear cell variant. Vet Pathol 2005; 42: 215-218. https://doi.org/10.1354/vp.42-2-215
  9. Pakhrin B, Kang MS, Bae IH, Park MS, Jee H, You MH, Kim JH, Yoon BI, Choi YK, Kim DY. Retrospective study of canine cutaneous tumors in Korea. J Vet Sci 2007; 8: 229-236. https://doi.org/10.4142/jvs.2007.8.3.229
  10. Saraiva AL, Gärtner F, Pires MA. Expression of p63 normal canine skin and primary cutaneous glandular carcinomas. Vet J 2008; 177: 136-140. https://doi.org/10.1016/j.tvjl.2007.03.027
  11. Simeonov RS, Simeonova GP. Use of quantitative analysis as a method for differentiation between canine cutaneous apocrine adenomas and apocrine carcinomas on cytological smears. J Vet Med A Physiol Pathol Clin Med 2007; 54: 542-544. https://doi.org/10.1111/j.1439-0442.2007.00973.x
  12. Simko E, Wilcock BP, Yager JA. A retrospective study of 44 canine apocrine sweat gland adenocarcinomas. Can Vet J 2003; 44: 38-42.
  13. Vos JH, van den Ingh TS, Ramaekers FC, Molenbeek RF, de Neijs M, van Mil FN, Ivanyi D. The expression of keratins, vimentin, neurofilament proteins, smooth muscle actin, neuron-specific enolase, and synaptophysin in tumors of the specific glands in the canine anal region. Vet Pathol 1993; 30: 352-361. https://doi.org/10.1177/030098589303000404