Korean Journal of Food Science and Technology (한국식품과학회지)

Korean Society of Food Science and Technology (한국식품과학회)
권호 표지
DOI QR코드

DOI QR Code

The Skin Protecting Effects of Ethanolic Extracts of Eggplant Peels

가지 외피 에탄올 추출물의 피부보호효과

  • Jo, Yu-Na (Department of Food Science and Technology, Institute of Agriculture and Life Science, Gyeonsang National University) ;
  • Jeong, Hee-Rok (Department of Food Science and Technology, Institute of Agriculture and Life Science, Gyeonsang National University) ;
  • Jeong, Ji-Hee (Department of Food Science and Technology, Institute of Agriculture and Life Science, Gyeonsang National University) ;
  • Heo, Ho-Jin (Department of Food Science and Technology, Institute of Agriculture and Life Science, Gyeonsang National University)
  • 조유나 (경상대학교 농업생명과학대학 식품공학과.농업생명과학연구원) ;
  • 정희록 (경상대학교 농업생명과학대학 식품공학과.농업생명과학연구원) ;
  • 정지희 (경상대학교 농업생명과학대학 식품공학과.농업생명과학연구원) ;
  • 허호진 (경상대학교 농업생명과학대학 식품공학과.농업생명과학연구원)
  • Received : 2011.09.06
  • Accepted : 2011.11.12
  • Published : 2012.02.29
Download PDF
⟨ Previous Next ⟩

Abstract

We investigated the in vitro antioxidant and antimelanogenesis effects of ethanol extracts from eggplant (Solanum melongena L.) peels. The total phenolics and chlorogenic acid in ethanol extracts were 2,465 mg/100 g and 2.08 mg/100 g, respectively. ABTS radical scavenging activity, ferric reducing/antioxidant power assay, and malondialdehyde (MDA) inhibitory effect of the extracts increased in a dose-dependent manner. In addition, the extracts generally showed strong UV absorption in the range of UV-B (290-320 nm). The $IC_{50}$ of mushroom tyrosinase inhibitory activity of ethanol extracts from eggplant peels was 870 ${\mu}g/mL$. Importantly, the melanin syntheses of B16/F10 melanoma cells were decreased by extracts in a concentration-dependent manner. Overall, these results suggest that eggplant peels can be potentially applied as a anti-melanogenic agent as well as an antioxidant resource.

본 연구에서는 총 페놀성 화합물 함량(2,465 mg/100 g)을 나타낸 가지 외피 에탄올 추출물의 in vitro 항산화 및 미백 효과를 알아보기 위해 다양한 연구를 진행하였다. 가지 외피 에탄올 추출물의 ABTS radical 소거활성과 FRAP assay결과 농도 의존적인 항산화 활성이 나타났으며 더불어 높은 세포 지질 과산화 억제활성을 보여주었다. 또한 가지 외피 에탄올 추출물의 자외선 흡수도를 측정한 결과 UV-A(320-400 nm)와 UV-B(290-320 nm)영역을 일정 수준 이상의 흡수 경향을 나타냈으며, 특히 UV-B(290-320 nm)영역에서 높은 흡수도를 보여주었다. 최종적으로, 미백효능을 알아보기 위해 mushroom tyrosinase 및 세포 내 멜라닌 함량 저해효과를 측정한 결과 모두 농도 의존적인 저해 효과를 보여주었다. 결국 본 연구결과를 종합해 볼 때 chlorogenic acid를 포함하여 다양한 페놀성 화합물을 함유한 가지 외피 에탄올 추출물은 in vitro 항산화 및 미백 효과를 가지는 기능성화장품 소재로서의 활용 가능성이 있을 것으로 판단된다.

Keywords

References

  1. Gilchrest BA. Skin aging and photoaging. Dermatol. Nurs. 2: 79- 82 (1990)
  2. Ha TY. Development of functional food materials for healthy life. Korean J. Crop Sci. 51: 26-39 (2006)
  3. Shin JY. Screening natural products that have activities against skin-aging. J. Korean Soc. Food Sci. Nutr. 14: 568-572 (2001)
  4. Kim BY, Kim TG, Kang WY, Baek H, Cheon HY, Kim DU. Functional cosmetic effect of porcine placeta. Korean Chem. Eng. Res. 48: 327-331 (2010)
  5. Yang HJ, Ahn YJ, Kim JH, Park SN. Antioxidative activity and component analysis of Quercus glauca leaf extract. J. Soc. Cosmet. Sci. 34: 189-200 (2008)
  6. Hong ES, Ahn GW, Jo BK. The study on the potential anti-aging properties of Prunella vulgaris extract in vitro and in vivo. J. Soc. Cosmet. Sci. Korea 34: 129-135 (2008)
  7. Giuseppe M, Giuseppe LR, Marta F, Antonietta DA, Gianluca F, Laura T, Federica C, Nazzareno A, Roverto L. Characterization of health-related compounds in eggplant (Solanum melongena L.) lines derived from introgression of allied species. J. Agr. Food Chem. 58: 7597-7603 (2010) https://doi.org/10.1021/jf101004z
  8. Nisha P, Abdul Nazar P, Jayamurthy P. A comparative study on antioxidant activities of different varieties of solanum melongena. Food Chem. Toxicol. 47: 2640-2644 (2009) https://doi.org/10.1016/j.fct.2009.07.026
  9. Jung HA, Park JC, Chung HY, Kim J, Choi JS. Antioxidant flavonoids and chlorogenic acid from the leaves of Eriobotrya japonica. Arch. Pharm. Res. 22: 213-218 (1999) https://doi.org/10.1007/BF02976549
  10. Close DC, Beadle CL. The ecophysiology of foliar anthocyanin. Bot. Rev. 69: 149-161 (2003) https://doi.org/10.1663/0006-8101(2003)069[0149:TEOFA]2.0.CO;2
  11. Matsubara K, Kaneyuki T, Mori M. Antiangiogenic activity of nasunin, an antioxidant anthocyanin, in eggplant peels. J. Agr. Food Chem. 53: 6272-6275 (2005) https://doi.org/10.1021/jf050796r
  12. Guimaraes PR, Galvao AMP, Batista1 CM, Azevedo GS, Oliveira RD, Lamounier RP, Freire N, Barros AMD, Sakurai E, Oliveira JP, Vieira EC, Alvarez-Leite JI. Eggplant (Solanum melongena) infusion has a modest and transitory effect on hypercholesterolemic subjects. Braz. J. Med. Biol. Res. 33: 1027-1036 (2000) https://doi.org/10.1590/S0100-879X2000000900006
  13. Jeon ER, Karki R, Kim DW. Inhibitory effect of chlorogenic acid on low-density lipoprotein oxidation induced by Cu ion. Korean J. Plant Res. 23: 487-553 (2010)
  14. Kim DO, Jeong SW, Lee CY. Antioxidant capacity of phenolic phytochemical from various cultivars of plums. Food Chem. 81: 321-326 (2003) https://doi.org/10.1016/S0308-8146(02)00423-5
  15. Jeong CH, Choi GN, Kim JH, Kwak JH, Kim DO, Kim YJ, Heo HJ. Antioxidant activities from the aerial parts of Platycodon grandiflorum. Food Chem. 118: 278-282 (2010) https://doi.org/10.1016/j.foodchem.2009.04.134
  16. Kim JS, Choi SY. Physicochemical properties and antioxidative activities of omija (Schizandra chiensis Baillon). Korean J. Food Nutr. 21: 35-42 (2008)
  17. Matsuda H, Higashio M, Nakai Y, Iinuma M, Kubo M, Frank L. Studies of cuticle drugs from natural sources. IV. Inhibitory effects of some Arctostaphylos plants on melanin biosynthesis. Biol. Pharm. Bull. 19: 153-156 (1996) https://doi.org/10.1248/bpb.19.153
  18. Kim NR, Lim YH, Park SW, Nam ES. Antimicrobial activities of the anti-acne compounds from natural sources. Korean Soc. Microbiol. Biotechnol. 37: 80-84 (2009)
  19. Park MK, Kim CH. Extraction of polyphenols from apple peels using cellulase and pectinase and estimation of antioxidant activity. J. Korean Soc. Food Sci. Nutr. 38: 535-540 (2009) https://doi.org/10.3746/jkfn.2009.38.5.535
  20. Hwang EY, Kong YH, Lee YC, Kim YC, Yoo KM, Jo YO, Choi SY. Comparison of phenolic compound contents between white and red ginseng and their inhibitory effect on melanin biosynthesis. J. Ginseng Res. 30: 82-87 (2006) https://doi.org/10.5142/JGR.2006.30.2.082
  21. Han YS, Jung ES. A study of correlation between antioxidant activity and whitening effect of plant extract. Korean Aesthetic. Soc. 1: 11-22 (2003)
  22. Jeong HR, Choi GN, Kim JH, Kwahk JH, Kim YS, Jeong CH, Kim DO, Heo HJ. Nutritional components and their antioxidative protection of neuronal cells of litchi (Litchi chinensis Sonn.) fruit pericarp. Korean J. Food Sci. Technol. 42: 481-487 (2010)
  23. Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of 'antioxidant power': The FRAP assay. Anal. Biochem. 239: 70-76 (1996) https://doi.org/10.1006/abio.1996.0292
  24. Osawa T. Novel natural antioxidant for utilization in food and viological system. pp. 241-251. In: Postharvest Biochemistry of Plank Food Material in the Tropics. Uritani I, Garcia VV, Mendoza EM (eds). Japan Scientific Societies Press, Tokyo, Japan. (1994)
  25. Uchida K, stadtman ER. Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra and intermolecular cross-linking reaction. J. Biol. Chem. 268: 6388-6393 (1993)
  26. Rhie SJ. The effect of lavender oil on the activity of antioxidant enzymes to ultraviolet-damaged skin. J. Kor. Soc. Cosm. 13: 467- 474 (2007)
  27. Sim GS, Kim JH, Lee BC, Lee DH, Lee GS, Pyo HB. Inhibitory effects on melanin production in B16 melamona cells of Sedum sarmentosum. Yakhak Hoeji 52: 165-171 (2008)
  28. Ha EH, Kim DK, Park JK, Chung YO, Kim HJ, Park NB. Melanogenesis inhibition effect of Rosa multiflora extracts in B16 melanoma cells. Korean J. Plant Res. 22: 317-322 (2009)
  29. Kazuya I, Noriaki K, Yukari K, Kyo M, Andtokio F. In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans. J. Agr. Food Chem. 52: 4893-4898 (2004) https://doi.org/10.1021/jf040048m
  30. Bennett DC, Cooper PJ, Hart IR. A line of non-tum-origenic mouse melanocytes, syngeneic with the B16 melanoma and requiring a tumour promoter for growth. Int. J. Cancer 39: 414- 418 (1987) https://doi.org/10.1002/ijc.2910390324
  31. Sung JK, Park SH, Seo DH, Lee JH, Hong SW, Hong SS. Antioxidative and skin-whitening effect of an aqueous extract of Salicornia hebacea. Biosci. Biotechnol. Biochem. 73: 552-556 (2009) https://doi.org/10.1271/bbb.80601

Cited by

  1. Protective Effect of Mulberry and Lithospermum erythrorhizon Extracts on Anti-aging against Photodamage vol.42, pp.11, 2013, https://doi.org/10.3746/jkfn.2013.42.11.1744
  2. Screening of Personalized Immunostimulatory Activities of Saengsik Materials and Products Using Human Primary Immune Cell vol.43, pp.9, 2014, https://doi.org/10.3746/jkfn.2014.43.9.1325
  3. Optimization of ultrasound-assisted extraction of total monomeric anthocyanin (TMA) and total phenolic content (TPC) from eggplant ( Solanum melongena L.) peel vol.31, 2016, https://doi.org/10.1016/j.ultsonch.2015.11.008
  4. Skin whitening activity of supercritical fluid extract from spent coffee in B16F10 melanoma cell vol.24, pp.3, 2015, https://doi.org/10.1007/s10068-015-0139-3
  5. Effects of Tarak, Korean Traditional Fermented Milk, on Proliferation of Immune Cells and Melanin Biosynthesis vol.44, pp.11, 2015, https://doi.org/10.3746/jkfn.2015.44.11.1759
  6. Nutritional Composition and Antioxidant·Antiacetylcholinesterase Activities of Blueberry (Vaccinium virgatum) vol.48, pp.4, 2014, https://doi.org/10.14397/jals.2014.48.4.241