The Korean Journal of Pain

  • 제25권1호
  • /
  • Pages.28-32
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  • 2012
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  • 2005-9159(pISSN)
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  • 2093-0569(eISSN)
대한통증학회 (The Korean Pain Society)
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Efficacy of Glycopyrrolate in Primary Hyperhidrosis Patients

  • Lee, Hyun-Ho (Department of Anesthesiology and Pain Medicine, Ajou University College of Medicine) ;
  • Kim, Do-Won (Department of Anesthesiology and Pain Medicine, Ajou University College of Medicine) ;
  • Kim, Do-Wan (Department of Anesthesiology and Pain Medicine, Ajou University College of Medicine) ;
  • Kim, Chan (Kichan Pain clinic)
  • 투고 : 2011.09.30
  • 심사 : 2011.12.16
  • 발행 : 2012.01.01
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초록

Background: Primary hyperhidrosis is a disorder of excessive sweating, which shares several features with anxiety disorders and has a negative impact on a patient's quality of life. Oral glycopyrrolate is one of the treatments available. There are a few published studies on the use of glycopyrrolate given orally in the treatment of hyperhidrosis. Methods: Thies is study was a review of case notes in a series of 36 patients with primary hyperhidrosis. We made a comparison between the Keller's scale score of a pre-glycopyrrolate medication group and the Keller's scale score f a post-glycopyrrolate medication group. The Milanez de Campos score, Short Form_36 (SF-36) score, Beck Depression Inventory (BDI) score, Beck Anxiety Inventory (BAI) score, and autonomic nervous system (ANS) scale score were also compared between the two groups. Results: In the post-glycopyrrolate medication group, there were declines in Keller's scale, and Milanez de Campos scale score and BAI score (P < 0.001). In addition, there were increases in SF_36 score in the post-glycopyrrolate medication group (P = 0.03) However, no changes were seen in, BDI score and ANS score in the post-glycopyrrolate medication group (P < 0.001). Conclusions: Glycopyrrolate is an effective initial method of treating primary hyperhidrosis that, reduces anxiety and improve patients' quality of life.

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참고문헌

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피인용 문헌

  1. Efficacy and safety of topical glycopyrrolate in patients with facial hyperhidrosis: a randomized, multicentre, double-blinded, placebo-controlled, split-face study vol.29, pp.2, 2015, https://doi.org/10.1111/jdv.12518
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