Journal of Periodontal and Implant Science

Korean Academy of Periodontology (대한치주과학회)
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Relationship between maternal periodontal disease and Apgar score of newborns

  • Shirmohammadi, Adileh (Dental and Periodontal Research Center, Tabriz University of Medical Sciences Faculty of Dentistry) ;
  • Abdollahifard, Sedigeh (Department of Transplantation, Tabriz University of Medical Sciences) ;
  • Chitsazi, Mohammad-Taghi (Dental and Periodontal Research Center, Tabriz University of Medical Sciences Faculty of Dentistry) ;
  • Behlooli, Sepideh (Department of Oral Medicine, Tabriz University of Medical Sciences Faculty of Dentistry)
  • Received : 2012.10.15
  • Accepted : 2012.11.28
  • Published : 2012.12.31
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Abstract

Purpose: The aim of this study was to evaluate the relationship between maternal periodontal disease and the health status of newborns using Apgar scores. Methods: One hundred pregnant women with periodontal disease were included in the case series and 100 pregnant women without periodontal disease were placed in the control group, respectively. The periodontal parameters of bleeding on probing (BOP), clinical attachment loss (CAL), probing depth (PD), birth weight, and Apgar scores were recorded in both groups. T-tests and Pearson's correlation coefficient were used to determine the birth weight odds ratio to analyze the relationship between the periodontal parameters of BOP, CAL, and PD on the one hand and an Apgar score of less than 7. An unpaired Student's t-test was used to analyze differences in means between the case and control groups using SPSS ver. 13. Results: The means of the ages, periodontal pocket depths, attachment loss, areas with BOP, Apgar score in the first 5 minutes and infant birth weight exhibited statistically significant differences between the case and control groups. The ratio of an Apgar score of <7 to periodontal disease was 3.14; the ratio of low birth weight risk in mothers with periodontal disease to that in mothers without periodontal disease was 2.74. Pearson's correlation coefficient revealed a significant correlation between the infant birth weight and BOP, CAL, and PD of the mother. In addition, there was a significant correlation between the Apgar score and BOP, CAL, and PD and also between the Apgar score and infant birth weight. Conclusions: The results of this study showed a significant relationship between periodontal disease and infant birth weight; in addition, there was a significant relationship between the periodontal indexes of BOP, CAL, and PD on the one hand and the Apgar score on the other.

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References

  1. Bobetsis YA, Barros SP, Offenbacher S. Exploring the relationship between periodontal disease and pregnancy complications. J Am Dent Assoc 2006;137 Suppl:7S-13S.
  2. Collins JG, Kirtland BC, Arnold RR, Offenbacher S. Experimental periodontitis retards hamster fetal growth [abstract]. J Dent Res 1995;74(Spec. Issue):158. Abstract no. 1171.
  3. Collins JG, Windley HW 3rd, Arnold RR, Offenbacher S. Effects of a Porphyromonas gingivalis infection on inflammatory mediator response and pregnancy outcome in hamsters. Infect Immun 1994;62:4356-61.
  4. Offenbacher S, Katz V, Fertik G, Collins J, Boyd D, Maynor G, et al. Periodontal infection as a possible risk factor for preterm low birth weight. J Periodontol 1996;67(10 Suppl):1103-13.
  5. Davenport ES, Williams CE, Sterne JA, Sivapathasundram V, Fearne JM, Curtis MA. The East London Study of Maternal Chronic Periodontal Disease and Preterm Low Birth Weight Infants: study design and prevalence data. Ann Periodontol 1998;3:213-21.
  6. Jeffcoat MK, Geurs NC, Reddy MS, Cliver SP, Goldenberg RL, Hauth JC. Periodontal infection and preterm birth: results of a prospective study. J Am Dent Assoc 2001;132: 875-80.
  7. Offenbacher S, Lieff S, Boggess KA, Murtha AP, Madianos PN, Champagne CM, et al. Maternal periodontitis and prematurity. Part I: Obstetric outcome of prematurity and growth restriction. Ann Periodontol 2001;6:164-74.
  8. Moore S, Ide M, Coward PY, Randhawa M, Borkowska E, Baylis R, et al. A prospective study to investigate the relationship between periodontal disease and adverse pregnancy outcome. Br Dent J 2004;197:251-8.
  9. Sundell TM, Beazley D, Patters MR, Carr TL, Blankenship JA, Mercer BM. Periodontal disease status and preterm birth in high risk women [abstract]. J Dent Res 2002;81(Spec. Issue):A230. Meeting abstract no. 1749.
  10. Mitchell-Lewis D, Engebretson SP, Chen J, Lamster IB, Papapanou PN. Periodontal infections and pre-term birth: early findings from a cohort of young minority women in New York. Eur J Oral Sci 2001;109:34-9.
  11. Lopez NJ, Smith PC, Gutierrez J. Periodontal therapy may reduce the risk of preterm low birth weight in women with periodontal disease: a randomized controlled trial. J Periodontol 2002;73:911-24.
  12. Avery ME, First LR. Determinants of Size and Maturity at Birth. In: Avery ME, First LR, editors. Pediatric medicine. Baltimore: Williams & Wilkins; 1988. p.130-45.
  13. Usher RH. The Special Problems of the Premature Infant. In: Avery GB, editor. Neonatalogy, pathophysiology and management of the newborn. Philadelphia: Lippincott; 1981. p.23-261.
  14. Bhat M, Nelson KB. Developmental enamel defects in primary teeth in children with cerebral palsy, mental retardation, or hearing defects: a review. Adv Dent Res 1989; 3:132-42.
  15. Casey BM, McIntire DD, Leveno KJ. The continuing value of the Apgar score for the assessment of newborn infants. N Engl J Med 2001;344:467-71.
  16. Al-Zahrani MS, Bissada NF, Borawskit EA. Obesity and periodontal disease in young, middle-aged, and older adults. J Periodontol 2003;74:610-5.
  17. Simon GE, Cunningham ML, Davis RL. Outcomes of prenatal antidepressant exposure. Am J Psychiatry 2002;159: 2055-61.
  18. Michalowicz BS, Hodges JS, DiAngelis AJ, Lupo VR, Novak MJ, Ferguson JE, et al. Treatment of periodontal disease and the risk of preterm birth. N Engl J Med 2006;355: 1885-94.
  19. Offenbacher S, Boggess KA, Murtha AP, Jared HL, Lieff S, McKaig RG, et al. Progressive periodontal disease and risk of very preterm delivery. Obstet Gynecol 2006;107:29-36.
  20. Jeffcoat MK, Hauth JC, Geurs NC, Reddy MS, Cliver SP, Hodgkins PM, et al. Periodontal disease and preterm birth: results of a pilot intervention study. J Periodontol 2003;74:1214-8.
  21. Dasanayake AP, Russell S, Boyd D, Madianos PN, Forster T, Hill E. Preterm low birth weight and periodontal disease among African Americans. Dent Clin North Am 2003;47: 115-25, x-xi.
  22. Shirmohammadi A, Pourabbas R, Bilan N, Chitsazi MT. Relationship between maternal periodontal condition and body size of newborns. Iran J Pediatr 2009;19:101-7.
  23. Meurman JH, Furuholm J, Kaaja R, Rintamaki H, Tikkanen U. Oral health in women with pregnancy and delivery complications. Clin Oral Investig 2006;10:96-101.
  24. Goepfert AR, Jeffcoat MK, Andrews WW, Faye-Petersen O, Cliver SP, Goldenberg RL, et al. Periodontal disease and upper genital tract inflammation in early spontaneous preterm birth. Obstet Gynecol 2004;104:777-83.

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  2. Reply on "Relationship between maternal periodontal disease and Apgar score of newborns" vol.43, pp.3, 2013, https://doi.org/10.5051/jpis.2013.43.3.143
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