Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Effect of ${\beta}$-Glucan Originated from Aureobasidium on Infected Dermal Wound Healing of the Normal Nude Mouse

Aureobasidium 유래 ${\beta}$-Glucan의 Nude Mouse 감염 피부에 대한 창상 치유 효과

  • Lee, Jung-Woo (College of Veterinary Medicine, Kyungpook National University) ;
  • Kwon, Young-Sam (College of Veterinary Medicine, Kyungpook National University) ;
  • Jang, Kwang-Ho (College of Veterinary Medicine, Kyungpook National University)
  • Accepted : 2012.12.17
  • Published : 2012.12.31
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Abstract

This experiment was applied to examine the effects of ${\beta}$-glucan originated from Aureobasidium on wound healing infected by 3 strains of bacteria in the normal nude mouse. From the results it was suggested that ${\beta}$-glucan has properties, which may be beneficial in the treatment of wound healing though it does not showed any antibacterial activities against wound infections by three strains such as S. aureus, S. pyogenes and P. aeruginosa. Therefore, it is considered that ${\beta}$-glucan will be promised as a new wound management.

Nude mouse의 세균 감염 피부에서 Aureobasidium 유래 ${\beta}$-glucan이 창상 치유에 미치는 영향을 평가하기 위해 본 실험을 실시하였다. 실험 결과, ${\beta}$-glucan은 S. aureus, S. pyogenes 및 P. aeruginosa 에 대해 살균 작용을 나타내지는 않았으나 대조군에 비해 감염 창상 크기를 현저히 감소시켰다. 따라서 ${\beta}$-glucan을 새로운 창상 치유 촉진제로서 고려해볼 수 있을 것이다.

Keywords

References

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