References
- Zhang Y, Ge R, Hardy MP. Androgen-forming stem Leydig cells: identification, function and therapeutic potential. Dis Markers 2008;24:277-86. https://doi.org/10.1155/2008/905025
- Chen L, Zhao Y, Zhang Y. Progress on the research of stem Leydig cell line in the testis of rodents. Wei Sheng Yan Jiu 2012;41:158-62.
- Wang C, Hikim AS, Ferrini M, Bonavera JJ, Vernet D, Leung A, Lue YH, Gonzalez-Cadavid NF, Swerdloff RS. Male reproductive ageing: using the brown Norway rat as a model for man. Novartis Found Symp 2002;242:82-95; discussion 95-7.
- Luo L, Chen H, Zirkin BR. Are Leydig cell steroidogenic enzymes differentially regulated with aging? J Androl 1996;17:509-15.
- Wu CY, Yu TJ, Chen MJ. Age related testosterone level changes and male andropause syndrome. Chang Gung Med J 2000;23: 348-53.
- Travison TG, Basaria S, Storer TW, Jette AM, Miciek R, Farwell WR, Choong K, Lakshman K, Mazer NA, Coviello AD, Knapp PE, Ulloor J, Zhang A, Brooks B, Nguyen AH, Eder R, LeBrasseur N, Elmi A, Appleman E, Hede-Brierley L, Bhasin G, Bhatia A, Lazzari A, Davis S, Ni P, Collins L, Bhasin S. Clinical meaningfulness of the changes in muscle performance and physical function associated with testosterone administration in older men with mobility limitation. J Gerontol A Biol Sci Med Sci 2011; 66:1090-9.
- Sattler F, Bhasin S, He J, Chou CP, Castaneda-Sceppa C, Yarasheski K, Binder E, Schroeder ET, Kawakubo M, Zhang A, Roubenoff R, Azen S. Testosterone threshold levels and lean tissue mass targets needed to enhance skeletal muscle strength and function: the HORMA trial. J Gerontol A Biol Sci Med Sci 2011;66:122-9.
- Chen RY, Ng KK. Self-referred older Asian males in a men's health clinic: the inter-relationships between androgens, metabolic parameters and quality of life measures. Aging Male 2010;13: 233-41. https://doi.org/10.3109/13685538.2010.487550
- Ibebunjo C, Eash JK, Li C, Ma Q, Glass DJ. Voluntary running, skeletal muscle gene expression, and signaling inversely regulated by orchidectomy and testosterone replacement. Am J Physiol Endocrinol Metab 2011;300:E327-40. https://doi.org/10.1152/ajpendo.00402.2010
- Nigro N, Christ-Crain M. Testosterone treatment in the aging male: myth or reality? Swiss Med Wkly 2012;142:w13539.
- Barqawi A, Crawford ED. Testosterone replacement therapy and the risk of prostate cancer. Is there a link? Int J Impot Res 2006; 18:323-8. https://doi.org/10.1038/sj.ijir.3901418
- Tenover JL. Male hormone replacement therapy including "andropause". Endocrinol Metab Clin North Am 1998;27:969-87, x. https://doi.org/10.1016/S0889-8529(05)70050-5
- Hu C, Kitts DD. Dandelion (Taraxacum officinale) flower extract suppresses both reactive oxygen species and nitric oxide and prevents lipid oxidation in vitro. Phytomedicine 2005;12:588-97. https://doi.org/10.1016/j.phymed.2003.12.012
- He W, Han H, Wang W, Gao B. Anti-influenza virus effect of aqueous extracts from dandelion. Virol J 2011;8:538. https://doi.org/10.1186/1743-422X-8-538
- Huang Y, Wu T, Zeng L, Li S. Chinese medicinal herbs for sore throat. Cochrane Database Syst Rev 2012;3:CD004877.
- Ovadje P, Chatterjee S, Griffin C, Tran C, Hamm C, Pandey S. Selective induction of apoptosis through activation of caspase-8 in human leukemia cells (Jurkat) by dandelion root extract. J Ethnopharmacol 2011;133:86-91. https://doi.org/10.1016/j.jep.2010.09.005
- Utter AC, Quindry JC, Emerenziani GP, Valiente JS. Effects of rooibos tea, bottled water, and a carbohydrate beverage on blood and urinary measures of hydration after acute dehydration. Res Sports Med 2010;18:85-96. https://doi.org/10.1080/15438620903321102
- Darvesh AS, Carroll RT, Bishayee A, Geldenhuys WJ, Van der Schyf CJ. Oxidative stress and Alzheimer's disease: dietary polyphenols as potential therapeutic agents. Expert Rev Neurother 2010;10:729-45. https://doi.org/10.1586/ern.10.42
- Bramati L, Aquilano F, Pietta P. Unfermented rooibos tea: quantitative characterization of flavonoids by HPLC-UV and determination of the total antioxidant activity. J Agric Food Chem 2003;51:7472-4. https://doi.org/10.1021/jf0347721
- Awoniyi DO, Aboua YG, Marnewick J, Brooks N. The effects of rooibos (Aspalathus linearis), green tea (Camellia sinensis) and commercial rooibos and green tea supplements on epididymal sperm in oxidative stress-induced rats. Phytother Res 2012;26: 1231-9. https://doi.org/10.1002/ptr.3717
- Marnewick JL, Rautenbach F, Venter I, Neethling H, Blackhurst DM, Wolmarans P, Macharia M. Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease. J Ethnopharmacol 2011;133: 46-52. https://doi.org/10.1016/j.jep.2010.08.061
- Baba H, Ohtsuka Y, Haruna H, Lee T, Nagata S, Maeda M, Yamashiro Y, Shimizu T. Studies of anti-inflammatory effects of rooibos tea in rats. Pediatr Int 2009;51:700-4. https://doi.org/10.1111/j.1442-200X.2009.02835.x
- Tan RS, Pu SJ. Impact of obesity on hypogonadism in the andropause. Int J Androl 2002;25:195-201. https://doi.org/10.1046/j.1365-2605.2002.00356.x
- Vermeulen A, Kaufman JM. Ageing of the hypothalamo-pituitarytesticular axis in men. Horm Res 1995;43:25-8. https://doi.org/10.1159/000184233
- Vermeulen A. Environment, human reproduction, menopause, and andropause. Environ Health Perspect 1993;101 Suppl 2:91-100. https://doi.org/10.1289/ehp.93101s291
- Bornman MS, Reif S. Serum testosterone levels in South African men and the onset of androgen decline in ageing males. S Afr J Surg 2007;45:62, 64.
- Moon C, Kim JS, Jang H, Lee HJ, Kim SH, Kang SS, Bae CS, Kim JC, Kim S, Lee Y, Shin T. Activation of Akt/protein kinase B and extracellular signal-regulated kinase in rats with acute experimental testicular torsion. J Vet Med Sci 2008;70:337-41. https://doi.org/10.1292/jvms.70.337
- Kim JY, Han EH, Kim HG, Oh KN, Kim SK, Lee KY, Jeong HG. Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells. Toxicol Lett 2010;193:200-8. https://doi.org/10.1016/j.toxlet.2010.01.011
- Yamashita S, Tai P, Charron J, Ko C, Ascoli M. The Leydig cell MEK/ERK pathway is critical for maintaining a functional population of adult Leydig cells and for fertility. Mol Endocrinol 2011;25:1211-22. https://doi.org/10.1210/me.2011-0059
- Walsh PC, Swerdloff RS. Biphasic effect of testosterone on spermatogenesis in the rat. Invest Urol 1973;11:190-3.
- Chen H, Liu J, Luo L, Zirkin BR. Dibutyryl cyclic adenosine monophosphate restores the ability of aged Leydig cells to produce testosterone at the high levels characteristic of young cells. Endocrinology 2004;145:4441-6. https://doi.org/10.1210/en.2004-0639
- Horstman AM, Dillon EL, Urban RJ, Sheffield-Moore M. The role of androgens and estrogens on healthy aging and longevity. J Gerontol A Biol Sci Med Sci 2012;67:1140-52. https://doi.org/10.1093/gerona/gls068
- Bormann CL, Smith GD, Padmanabhan V, Lee TM. Prenatal testosterone and dihydrotestosterone exposure disrupts ovine testicular development. Reproduction 2011;142:167-73. https://doi.org/10.1530/REP-10-0210
- Sofikitis N, Giotitsas N, Tsounapi P, Baltogiannis D, Giannakis D, Pardalidis N. Hormonal regulation of spermatogenesis and spermiogenesis. J Steroid Biochem Mol Biol 2008;109:323-30. https://doi.org/10.1016/j.jsbmb.2008.03.004
- Schwartz E, Holtorf K. Hormone replacement therapy in the geriatric patient: current state of the evidence and questions for the future. Estrogen, progesterone, testosterone, and thyroid hormone augmentation in geriatric clinical practice: part 1. Clin Geriatr Med 2011;27:541-59. https://doi.org/10.1016/j.cger.2011.07.013
- Schwartz E, Morelli V, Holtorf K. Hormone replacement therapy in the geriatric patient: current state of the evidence and questions for the future--estrogen, progesterone, testosterone, and thyroid hormone augmentation in geriatric clinical practice: part 2. Clin Geriatr Med 2011;27:561-75. https://doi.org/10.1016/j.cger.2011.07.004
- Heinemann LA. Aging Males' Symptoms scale: a standardized instrument for the practice. J Endocrinol Invest 2005;28:34-8. https://doi.org/10.1007/BF03345527
- Miwa Y, Kaneda T, Yokoyama O. Correlation between the Aging Males' Symptoms scale and sex steroids, gonadotropins, dehydroepiandrosterone sulfate, and growth hormone levels in ambulatory men. J Sex Med 2006;3:723-6. https://doi.org/10.1111/j.1743-6109.2006.00277.x
- Kawa G, Taniguchi H, Kinoshita H, Matsuda T, Urakami M, Sawaragi I. Aging Male Symptoms and serum testosterone levels in healthy Japanese middle-aged men. Nihon Hinyokika Gakkai Zasshi 2008;99:645-51.
Cited by
- (rooibos) on male rat reproductive functions vol.46, pp.8, 2013, https://doi.org/10.1111/and.12158
- (tea) vol.47, pp.1, 2014, https://doi.org/10.1111/and.12221
- Anti-diabetic effect of dandelion leaves and roots in type two diabetic patients vol.45, pp.3, 2015, https://doi.org/10.1108/NFS-01-2015-0001
- vol.59, pp.4, 2016, https://doi.org/10.3839/jabc.2016.052
- extract on the levels of steroidogenic enzymes in mouse Leydig cells vol.22, pp.6, 2018, https://doi.org/10.1080/19768354.2018.1494628
- Establishment of the Male Menopause Animal Model Using Rats vol.52, pp.5, 2018, https://doi.org/10.14397/jals.2018.52.5.91
- MR-10 Enhances Men's Health by Improving Endogenous Male Sex Hormone Generation pp.1557-7600, 2018, https://doi.org/10.1089/jmf.2018.4201
- Polycyclic Aromatic Hydrocarbons and Endocrine Disruption: Role of Testicular Gap Junctional Intercellular Communication and Connexins pp.1096-0929, 2019, https://doi.org/10.1093/toxsci/kfz023
- Validity and reliability of male andropause symptoms self-assessment questionnaire among elderly males in Khuzestan province of Iran vol.4, pp.4, 2013, https://doi.org/10.4103/0976-7800.122258
- Effects of enzymatic hydrolysate from seahorse Hippocampus abdominalis on testosterone secretion from TM3 Leydig cells and in male mice vol.59, pp.6, 2012, https://doi.org/10.1007/s13765-016-0237-9
- Effect of Glyphaea brevis twigs extract on cell viability, apoptosis induction and mitochondrial membrane potential in TM3 Leydig cells vol.51, pp.7, 2012, https://doi.org/10.1111/and.13312
- Studies on the physicochemical characteristics of the New Zealand deer’s tail, Cervus elaphus var. scoticus (III) vol.28, pp.4, 2019, https://doi.org/10.1007/s10068-019-00558-z
- Cranberry Powder Attenuates Benign Prostatic Hyperplasia in Rats vol.23, pp.12, 2020, https://doi.org/10.1089/jmf.2020.4779
- Alleviating effects of the mixture of Elaeagnus multiflora and Cynanchum wilfordii extracts on testosterone deficiency syndrome vol.63, pp.4, 2020, https://doi.org/10.3839/jabc.2020.059