Korean Circulation Journal

The Korean Society of Cardiology (대한심장학회)
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A Case of Severe Pulmonary Thromboembolism in a Young Male With Klinefelter Syndrome

  • Kang, Byung-Soo (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine) ;
  • Cho, Deok-Kyu (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine) ;
  • Koh, Won-Jun (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine) ;
  • Yoo, Seung-Hoon (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine) ;
  • Won, Ki-Bum (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine) ;
  • Cho, Yun-Hyeong (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine) ;
  • Hwang, Eui-Seock (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine) ;
  • Koh, Jong-Hoon (Division of Cardiology, Cardiovascular Center, Myongji Hospital, Kwandong University College of Medicine)
  • Published : 2012.08.31
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Abstract

A young male patient diagnosed with Klinefelter syndrome was admitted to our hospital via the emergency room with chief complaints of acute chest pain and dyspnea. Pulmonary thromboembolism was diagnosed from his chest CT images. His symptoms improved after he underwent thrombolysis and anticoagulation treatment. Klinefelter syndrome has a tendency towards hypercoagulability due to hormonal imbalance and one or more inherited thromophilic factors. Thus, Klinefelter syndrome patients with a past medical history of venous thromboembolism require continuous oral anticoagulation therapy for a period of at least six months.

Keywords

References

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Cited by

  1. The Effect of PAI-1 Gene Variants and PAI-1 Plasma Levels on Development of Thrombophilia in Patients With Klinefelter Syndrome vol.12, pp.6, 2018, https://doi.org/10.1177/1557988318801158
  2. Massive Pulmonary Emboli in Klinefelter Syndrome: A Rare Case Report vol.11, pp.4, 2012, https://doi.org/10.5812/aapm.117808