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직장-S상 결장접합부 거대 궤양을 통해 진단된 전신홍반 루푸스 1예

A Case of Systemic Lupus Erythematosus Presenting as a Large Rectosigmoid Ulcer

  • 유인경 (고려대학교 의과대학 류마티스내과) ;
  • 유서희 (고려대학교 의과대학 류마티스내과) ;
  • 최성재 (고려대학교 의과대학 류마티스내과) ;
  • 구자설 (고려대학교 의과대학 소화기내과) ;
  • 이영호 (고려대학교 의과대학 류마티스내과) ;
  • 지종대 (고려대학교 의과대학 류마티스내과) ;
  • 송관규 (고려대학교 의과대학 류마티스내과)
  • Yoo, In-Kyung (Division of Rheumatology, Department of Internal Medicine, Korea University Medical Center, Korea University College of Medicine) ;
  • Yoo, Seu-Hee (Division of Rheumatology, Department of Internal Medicine, Korea University Medical Center, Korea University College of Medicine) ;
  • Choi, Sung-Jae (Division of Rheumatology, Department of Internal Medicine, Korea University Medical Center, Korea University College of Medicine) ;
  • Koo, Ja-Seol (Division of Gastroenterology, Department of Internal Medicine, Korea University Medical Center, Korea University College of Medicine) ;
  • Lee, Young-Ho (Division of Rheumatology, Department of Internal Medicine, Korea University Medical Center, Korea University College of Medicine) ;
  • Ji, Jong-Dae (Division of Rheumatology, Department of Internal Medicine, Korea University Medical Center, Korea University College of Medicine) ;
  • Song, Kwan-Kyu (Division of Rheumatology, Department of Internal Medicine, Korea University Medical Center, Korea University College of Medicine)
  • 발행 : 2012.02.01

초록

저자들은 비특이적인 위장 증상으로 내원한 전신홍반루푸스 환자에서 S상결장 부위의 부분-완전 폐색을 동반한 커다란 직장궤양을 발견하였고, 기저 질환으로 루푸스를 진단하고 경구스테로이드 치료로 호전되었기에 이를 보고하는 바이다.

Systemic lupus erythematosus (SLE) is a multi-system inflammatory disorder that has many symptoms. Gastrointestinal symptoms are common, while colonic involvement in the form of ischemic colitis or a colonic ulcer is rare in SLE. The differential diagnosis of ischemic proctitis with ulceration includes an infected ulcer, ulcerative colitis, Crohn's disease, solitary rectal ulcer colitis, malignant tumor, and lupus colitis. Here, we report a 22-year-old male with abdominal pain and diarrhea, who had a huge rectal ulcer that nearly obstructed the rectosigmoid junction. This turned out to be a rare gastrointestinal manifestation of lupus. He recovered after being treated with high-dose oral steroids. Our case demonstrates that a rectal ulcer is a rare, but important, complication of SLE and can be the initial clinical manifestation of the disease.

키워드

참고문헌

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피인용 문헌

  1. Rectal Ulcer Developed in Systemic Lupus Erythematosus without Ischemic Colitis vol.73, pp.5, 2012, https://doi.org/10.4166/kjg.2019.73.5.299